Patents by Inventor Dasheng Zhang

Dasheng Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DETECTING AND QUANTIFYING RNA
    Publication number: 20240392302
    Abstract: An aptamer nucleic acid molecule, a complex containing the aptamer and a small fluorophore molecule, a method for detecting intracellular or extracellular RNA, DNA or other target molecules using the aptamer nucleic acid molecule, and a kit containing the aptamer. The aptamer of the present disclosure can specifically bind with a small fluorophore molecule, and can significantly improve the fluorescence intensity thereof under the excitation of light of suitable wavelength.
    Type: Application
    Filed: August 5, 2022
    Publication date: November 28, 2024
    Inventor: Dasheng ZHANG
  • FLUORESCENT DYE, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20240352309
    Abstract: A fluorescent dye as represented by formula (I), and a preparation method therefor and the use thereof. The fluorescent dye comprises an electron donor part D, a conjugate system E and an electron acceptor part A. The fluorescent dye with a long-wavelength emission capability has low background fluorescence, good water solubility, a sensitive viscosity response, and an adjustable wavelength.
    Type: Application
    Filed: August 5, 2022
    Publication date: October 24, 2024
    Inventor: Dasheng ZHANG
  • FLUORESCENT DYE, AND PREPARATION METHOD AND USES THEREOF
    Publication number: 20230141569
    Abstract: A fluorescent dye, a preparation method and uses thereof, wherein the fluorescent dye has the advantages of sensitivity and specificity to viscosity response, low background fluorescence and the like, and can also be used as a fluorescence activated and lightened-up probe for fluorescence labeling, quantification or detection of proteins, enzymes or nucleic acids.
    Type: Application
    Filed: March 16, 2021
    Publication date: May 11, 2023
    Inventor: Dasheng ZHANG
  • APTAMER NUCLEIC ACID MOLECULE, AND COMPLEX AND APPLICATION THEREOF
    Publication number: 20230002769
    Abstract: The present application relates to an aptamer nucleic acid molecule, a complex containing the aptamer nucleic acid molecules, a method of detecting intracellular or extracellular RNA, DNA or other target molecules, and a kit containing the aptamer. The aptamer of the present application is capable of specifically binding a kind of fluorophore micromolecules, and can significantly enhance fluorescence intensity under excitation light of appropriate wavelength.
    Type: Application
    Filed: April 28, 2020
    Publication date: January 5, 2023
    Inventors: Yi YANG, Linyong ZHU, Xianjun CHEN, Dasheng ZHANG, Ni SU, Qiuning LIN
  • FLUORESCENT DYE, PREPARATION METHOD AND USES THEREOF
    Publication number: 20220214351
    Abstract: A fluorescent dye, as well as a preparation method and uses thereof, wherein the fluorescent dye is sensitive and specific to viscosity and has low background fluorescence; it can also be used as a fluorescent activated and lighted probe used for fluorescent labeling, quantification or monitoring of protein, enzymes or nucleic acid.
    Type: Application
    Filed: April 27, 2020
    Publication date: July 7, 2022
    Inventors: Linyong ZHU, Yi YANG, Dasheng ZHANG, Xianjun CHEN, Qiuning LIN, Ni SU
  • Fluorescent dye and preparation method and use thereof
    Patent number: 11365203
    Abstract: Provided are a fluorescent dye and a preparation process and use thereof. The fluorescent dye is able to emit a long wavelength, is sensitive and specific to viscosity, and is used for a wide range of purposes, such as viscosity testing, fluorescent labeling, quantification or detection of proteins, enzymes or nucleic acids. In addition, it can be used as a fluorescent-activated probe.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: June 21, 2022
    Assignee: FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY LTD.
    Inventors: Linyong Zhu, Yi Yang, Dasheng Zhang, Zengmin Du, Bingkun Bao, Qiuning Lin, Yan Li, Xianjun Chen, Lipeng Yang, Chunyan Bao
  • Fluorescent probe and preparation method and use thereof
    Patent number: 11209437
    Abstract: Provided are a fluorescent probe and a preparation process and the use thereof. The fluorescent probe is sensitive and specific to viscosity, and can be used for specific fluorescent labeling of proteins, and can also be used for quantification, detection or kinetic studies of proteins, and the imaging of cells, tissues and living bodies.
    Type: Grant
    Filed: July 18, 2017
    Date of Patent: December 28, 2021
    Assignee: FLUORESCENCE DIAGNOSIS (SHANGHAI) BIOTECH COMPANY
    Inventors: Linyong Zhu, Yi Yang, Dasheng Zhang, Zengmin Du, Bingkun Bao, Qiuning Lin, Xianjun Chen, Lipeng Yang, Chunyan Bao, Yihui Ge, Renmei Liu, Zhengda Chen, Sitong Zhang, Ningfeng Li, Xin Hua
  • FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20210382060
    Abstract: Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe sensitively and specifically responds to viscosity, and can be used for the specific fluorescence labeling of proteins as well as in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.
    Type: Application
    Filed: April 30, 2019
    Publication date: December 9, 2021
    Applicant: SHANGHAI GLORY CAPITAL MANAGEMENT LTD.
    Inventors: Linyong ZHU, Yi YANG, Bingkun BAO, Ni SU, Dasheng ZHANG, Xianjun CHEN, Qiuning LIN, Chunyan BAO
  • FLUORESCENT PROBE, PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20200248069
    Abstract: Provided are a fluorescent probe, a preparation method therefor and a use thereof. The fluorescent probe responds to viscosity sensitively and specifically, can be used for the specific fluorescence labeling of proteins and can also be used in the quantification, detection or kinetic study of proteins and the imaging of cells, tissues and living bodies.
    Type: Application
    Filed: September 29, 2018
    Publication date: August 6, 2020
    Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Linyong Zhu, Yi Yang, Bingkun Bao, Chenxia Zhang, Dasheng Zhang, Chunyan Bao, Qiuning Lin, Ningfeng Li, Xin Hua, Yongliang Zhao, Renmei Liu, Zhengda Chen, Yuying Sun
  • FLUORESCENT DYE AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20190241584
    Abstract: Provided are a fluorescent dye and a preparation process and use thereof. The fluorescent dye is able to emit a long wavelength, is sensitive and specific to viscosity, and is used for a wide range of purposes, such as viscosity testing, fluorescent labeling, quantification or detection of proteins, enzymes or nucleic acids. In addition, it can be used as a fluorescent-activated probe.
    Type: Application
    Filed: July 18, 2017
    Publication date: August 8, 2019
    Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Linyong Zhu, Yi Yang, Dasheng Zhang, Zengmin Du, Bingkun Bao, Qiuning Lin, Yan Li, Xianjun Chen, Lipeng Yang, Chunyan Bao
  • FLUORESCENT PROBE AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20190187144
    Abstract: Provided are a fluorescent probe and a preparation process and the use thereof. The fluorescent probe is sensitive and specific to viscosity, and can be used for specific fluorescent labeling of proteins, and can also be used for quantification, detection or kinetic studies of proteins, and the imaging of cells, tissues and living bodies.
    Type: Application
    Filed: July 18, 2017
    Publication date: June 20, 2019
    Applicant: EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Linyong Zhu, Yi Yang, Dasheng Zhang, Zengmin Du, Bingkun Bao, Qiuning Lin, Xianjun Chen, Lipeng Yang, Chunyan Bao, Yihui Ge, Renmei Liu, Zhengda Chen, Sitong Zhang, Ningfeng Li, Xin Hua