Patents by Inventor Datao Liu

Datao Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-INTERLEUKIN-11 ANTIBODY AND USE THEREOF
    Publication number: 20250197488
    Abstract: Disclosed is an anti-interleukin 11 (IL-11) antibody or a fragment thereof, which has high affinity for antigen IL-11, can block the formation of an IL-11/IL-11R?/GP130 complex and inhibit the activation of the STAT3 signal pathway. Therefore, the anti-interleukin 11 antibody or the fragment thereof can effectively neutralize the activity of IL-11, and can be used for preventing, treating and/or improving diseases or conditions related to IL-11 expression (including overexpression).
    Type: Application
    Filed: January 29, 2023
    Publication date: June 19, 2025
    Inventors: Dadi ZENG, Datao LIU, Xun GUI, Rongjuan WANG, Weining LU, Shasha JIAO, Chang ZHANG, Shuang WANG
  • ANTIBODY DRUG CONJUGATE TARGETING NECTIN 4 AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20240226318
    Abstract: An antibody-drug conjugate targeting a poliovirus receptor-like molecule 4 (Nectin-4). The antibody-drug conjugate can be used for preparing a drug for treating Nectin-4-related diseases. The antibody-drug conjugate has strong targeting properties to Nectin-4 and a strong endocytosis effect via the target, and has an excellent tumor-killing effect.
    Type: Application
    Filed: April 29, 2022
    Publication date: July 11, 2024
    Inventors: Wei ZHOU, Xiaoding TAN, Datao LIU
  • PREPARATION PROCESS OF RECOMBINANT HUMAN P43 PROTEIN
    Publication number: 20100062488
    Abstract: A process for producing human p43 protein is provided, in which the p43 protein can be used as a drug for treating solid tumor.
    Type: Application
    Filed: January 17, 2008
    Publication date: March 11, 2010
    Applicant: Sine Pharmaceutical Laboratories
    Inventors: Datao Liu, Xiaoding Tan, Linda Hu, Yan Wang, Xi Zhu
  • Pharmaceutical Composition Comprising P43 Protein for the Treatment of Gastric Adenocarcinoma
    Publication number: 20090324573
    Abstract: A pharmaceutical composition for the treatment of gastric adenocarcinoma is provided, wherein the pharmaceutical composition comprises p43 protein and pharmaceutically acceptable carriers, and does not comprise paclitaxel. A use of p43 protein for the treatment of gastric adenocarcinoma is also provided.
    Type: Application
    Filed: May 26, 2009
    Publication date: December 31, 2009
    Inventors: Datao Liu, Xiaoding Tan, Xi Zhu, Yan Wang, Linda Hu