Abstract: A gimbal assembly includes a gimbal encoder having a gimbal encoder having a lower fixed section and an upper rotatable section, the gimbal encoder defining a gimbal aperture through an axis of rotation of the upper rotatable section; a liquid crystal display (LCD) housing configured to hold an LCD, the LCD housing defining a flat circular body and an upper stem portion extending perpendicularity downward from the center of the circular body, the upper stem portion being sized to be placed vertically downwards into an upper portion of the gimbal aperture; and a lower adapter defining a lower stem portion sized to be placed vertically upwards into a lower portion of the gimbal aperture, wherein the upper stem portion and the lower stem portion are configured to interface with one another to collectively form a two-piece stem.

Abstract: The present invention relates to a pre-lyophilized composition comprising bendamustine or its pharmaceutically acceptable salt, a pharmaceutically acceptable carrier, an organic solvent and water. Furthermore, the present invention provides a stable pharmaceutical composition comprising bendamustine hydrochloride prepared from such pre-lyophilized composition, a process for preparing such composition; and its use in the treatment of cancer.