Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods determine that a mobile device associated with the electric bicycle is in contact with a mount disposed on the electric bicycle, and cause a lock assembly to unlock the electric bicycle in response to the determination that the mobile device is in contact with the mount.

Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.

Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.

Abstract: Pharmaceutical formulations including an inclusion complex of an API with a cyclic oligomer, and methods of forming such pharmaceutical formulations are described.

Abstract: The present disclosure relates to pharmaceutical formulations including abiraterone and a cyclic oligomer, as well as tablets including such pharmaceutical formulations, methods of forming such pharmaceutical formulations, and methods of administering such pharmaceutical formulations or tablets.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods provide a communication system for an electric bicycle that includes a communication device that facilitates wireless communications between the electric bicycle and a wireless network, and an antenna coupled to the communication device and at least partially integrated into a frame component of the electric bicycle.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods provide a bike-supported communication device that communicates with a wireless network via one or more wireless communication protocols, where the communication device is configured to manage communications between the wireless network and various components of the electric bicycle. The communication device can include a bicycle communications component that facilitates communications between the communication device and components of the electric bicycle, and a network communications component that facilitates communications between the electric bicycle and the wireless network.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods provide a bike-supported communication device that is integrated into a bike lock, lock, or lock assembly.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods perform security actions for electric bicycle in response to potential theft or tampering events at the electric bicycle. The systems and methods can select actions to perform based on information from multiple different sensors, from polling sensors or components of the bicycle for information, based on a context of the event, and so on.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods provide a lock assembly for an electric bicycle, having a lock module that is configured to lock a rear wheel of the electric bicycle and a communication module that facilitates wireless communications between the electric bicycle and a communications network.

Abstract: Various embodiments provide for a bike-supported communication network that manages and facilitates communications between components of an electric bicycle and a wireless network. In some embodiments, the systems and methods determine that a mobile device associated with the electric bicycle is in contact with a mount disposed on the electric bicycle, and cause a lock assembly to unlock the electric bicycle in response to the determination that the mobile device is in contact with the mount.

Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.

Abstract: An electric bicycle control device, and associated display device, are described. The control device, in some embodiments, includes an LED (light emitting diode) indicator (e.g., alphanumeric display) that presents information to riders of the electric bicycle, as well as various control buttons that facilitate rider control of the electric bicycle. The control device is associated with a display device, which presents additional or complementary information about the electric bicycle, such as information that is presented based on input received via the control device from the rider.

Abstract: The present disclosure relates to pharmaceutical formulations including a weakly basic drug and an ionic polymer in an amorphous solid dispersion, as well as methods of forming such pharmaceutical formulations, and methods of administering such pharmaceutical formulations.

Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can he further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.

Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.

Abstract: The disclosure provides for improved pharmaceutical compositions containing an active pharmaceutical ingredient and a non-polymeric lubricant and methods of manufacturing the same. In particular, the compositions are prepared using thermal processing or solvent sprying and provide improved properties as well as more efficient methods of manufacture.