Patents by Inventor Dave Alan Miller

Dave Alan Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SUBSTITUTED 3-ISOBUTYL-9,10-DIMETHOXY-1,3,4,6,7,11B-HEXAHYDRO-2H-PYRIDO[2,1-a]ISOQUINOLIN-2-OL COMPOUNDS, THEIR SYNTHESIS, AND USE THEREOF
    Publication number: 20210087191
    Abstract: The invention relates to substituted 3-isobutyl-9,10-dimethoxy-1,3,4,6,7,11b-hexahydro-2H-pyrido[2,1-a]isoquinolin-2-ol compounds, their synthesis, pharmaceutical compositions containing them, and methods of using them in the treatment of disorders benefiting from inhibition of vesicular monoamine transporter 2 (VMAT2).
    Type: Application
    Filed: December 4, 2020
    Publication date: March 25, 2021
    Inventors: Dave Alan MILLER, Daniel J. ELLENBERGER, Esmir GUNIC, Jean-Luc GIRARDET, Angela SPANGENBERG
  • IMPROVED FORMULATIONS OF VEMURAFENIB AND METHODS OF MAKING THE SAME
    Publication number: 20170333404
    Abstract: The disclosure provides for improved pharmaceutical compositions containing vemurafenib and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
    Type: Application
    Filed: November 3, 2015
    Publication date: November 23, 2017
    Applicant: DISPERSOL TECHNOLOGIES, LLC
    Inventors: Dave Alan MILLER, Justin Martin KEEN, Chris BROUGH, Sandra U. KUCERA, Daniel J. ELLENBERGER
  • PHARMACEUTICAL COMPOSITION FOR TREATING HCV INFECTIONS
    Publication number: 20130331314
    Abstract: The present invention relates to a granular pharmaceutical composition comprising an HCV protease inhibitor and at least one poloxamer.
    Type: Application
    Filed: August 23, 2013
    Publication date: December 12, 2013
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Andreas Leiminer, Kai Lindenstruth, Dave Alan Miller, Emmanuel Scheubel, Navnit Hargovindas Shah
  • PROCESS FOR CONTROLLED CRYSTALLIZATION OF AN ACTIVE PHARMACEUTICAL INGREDIENT FROM SUPERCOOLED LIQUID STATE BY HOT MELT EXTRUSION
    Publication number: 20120213827
    Abstract: A process for controlling the crystallization of certain hydrophobic active pharmaceutical ingredients (APIs) from a supercooled liquid state by hot-melt extrusion processing is described. Also described is a pharmaceutical composition comprising a solid crystalline dispersion of a cholesterol ester transfer protein inhibitor in a hydrophilic excipient matrix. In the process of the present invention, the API is fed to an extrusion system in a crystalline state contemporaneously with carrier excipients where it is first converted to a non-crystalline state by the application of heat and then subsequently recrystallized in-situ by the removal of heat and application of shear. Recrystallization of the API is controlled by carrier formulation design and the hot-melt extrusion process parameters; i.e. barrel temperature profile, feed rate, etc.
    Type: Application
    Filed: February 17, 2012
    Publication date: August 23, 2012
    Inventors: Ashish Chatterji, Dipen Desai, Dave Alan Miller, Harpreet K. Sandhu, Navnit H. Shah
  • PHARMACEUTICAL COMPOSITION FOR TREATING HCV INFECTIONS
    Publication number: 20120114751
    Abstract: The present invention relates to a granular pharmaceutical composition comprising an HCV protease inhibitor and at least one poloxamer.
    Type: Application
    Filed: November 8, 2011
    Publication date: May 10, 2012
    Inventors: Andreas Leiminer, Kai Lindenstruth, Dave Alan Miller, Emmanuel Scheubel, Navnit Hargovindas Shah