Patents by Inventor Dave Miller

Dave Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190142756
    Abstract: The disclosure provides for improved pharmaceutical compositions containing an active pharmaceutical ingredient and a non-polymeric lubricant and methods of manufacturing the same. In particular, the compositions are prepared using thermal processing or solvent spraying and provide improved properties as well as more efficient methods of manufacture.
    Type: Application
    Filed: November 9, 2018
    Publication date: May 16, 2019
    Applicant: DISPERSOL TECHNOLOGIES, LLC
    Inventors: Dave A. MILLER, Daniel J. ELLENBERGER, Sandra U. SCHILLING
  • Patent number: 10265301
    Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
    Type: Grant
    Filed: June 17, 2016
    Date of Patent: April 23, 2019
    Assignee: DISPERSOL TECHNOLOGIES, LLC
    Inventors: Dave A. Miller, Justin M. Keen, Sandra U. Kucera
  • Patent number: 10258608
    Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 16, 2019
    Assignee: DISPERSOL TECHNOLOGIES, LLC
    Inventors: Dave A. Miller, Justin M. Keen, Sandra U. Kucera
  • Publication number: 20190091339
    Abstract: The present disclosure relates to pharmaceutical formulations including abiraterone and a cyclic oligomer, as well as tablets including such pharmaceutical formulations, methods of forming such pharmaceutical formulations, and methods of administering such pharmaceutical formulations or tablets.
    Type: Application
    Filed: September 20, 2018
    Publication date: March 28, 2019
    Applicant: DISPERSOL TECHNOLOGIES, LLC
    Inventors: Dave Miller, Urvi Gala
  • Publication number: 20180360850
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Application
    Filed: June 19, 2018
    Publication date: December 20, 2018
    Applicants: BOARD OF REGENTS, THE UNIVERISTY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLC
    Inventors: Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
  • Patent number: 10131433
    Abstract: A system and method for aircraft passenger seating allows traditional passenger seats, which have fixed configurations, to meet new specifications. A bottom frame and backrest frame from a traditional passenger seat is used to form a new passenger seat. Features, such as improved cushioning, telescopic or fixed headrests, rotatable or fixed footrests and improve armrest assemblies may be added as part of the new passenger seat.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: November 20, 2018
    Inventors: Ron Larabie, Dave Miller
  • Publication number: 20180280302
    Abstract: The present invention refers to a method for producing storage-stable solid dispersions of poorly soluble pharmaceutically active compounds comprising polyvinyl alcohol as carrier matrix. The invention also refers to the prepared compositions and their use.
    Type: Application
    Filed: December 22, 2015
    Publication date: October 4, 2018
    Applicant: MERCK PATENT GMBH
    Inventors: Shawn KUCERA, Dieter LUBDA, Dave MILLER, Chris BROUGH
  • Patent number: 10022385
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: July 17, 2018
    Assignees: Board of Regents, The University of Texas System, DisperSol Technologies, LLC
    Inventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. Dinunzio, Robert O. Williams, III
  • Publication number: 20180029715
    Abstract: A system and method for aircraft passenger seating allows traditional passenger seats, which have fixed configurations, to meet new specifications. A bottom frame and backrest frame from a traditional passenger seat is used to form a new passenger seat. Features, such as improved cushioning, telescopic or fixed headrests, rotatable or fixed footrests and improve armrest assemblies may be added as part of the new passenger seat.
    Type: Application
    Filed: July 28, 2016
    Publication date: February 1, 2018
    Inventors: Ron Larabie, Dave Miller
  • Publication number: 20170296514
    Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
    Type: Application
    Filed: June 28, 2017
    Publication date: October 19, 2017
    Applicant: DISPERSOL TECHNOLOGIES, LLC
    Inventors: Dave A. MILLER, Justin M. KEEN, Sandra U. KUCERA
  • Patent number: 9730894
    Abstract: A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does not dissolve the drug-containing particles during extrusion. As a result, a majority or at least 90% wt. of the drug-containing particles in the extrudate are deaggregated during extrusion into essentially primary crystalline and/or amorphous particles. PEO is a suitable carrier material for drugs insoluble in the solid state in this carrier. Various functional excipients can be included in the carrier system to stabilize the particle size and physical state of the drug substance in either a crystalline and/or amorphous state. The carrier system is comprised of at least one thermal binder, and may also contain various functional excipients, such as: super-disintegrants, antioxidants, surfactants, wetting agents, stabilizing agents, retardants, or similar functional excipients.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: August 15, 2017
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Dave A. Miller, Jason T. McConville, James W. McGinity, Robert O. Williams, III
  • Publication number: 20170119669
    Abstract: A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does not dissolve the drug-containing particles during extrusion. As a result, a majority or at least 90% wt. of the drug-containing particles in the extrudate are deaggregated during extrusion into essentially primary crystalline and/or amorphous particles. PEO is a suitable carrier material for drugs insoluble in the solid state in this carrier. Various functional excipients can be included in the carrier system to stabilize the particle size and physical state of the drug substance in either a crystalline and/or amorphous state. The carrier system is comprised of at least one thermal binder, and may also contain various functional excipients, such as: super-disintegrants, antioxidants, surfactants, wetting agents, stabilizing agents, retardants, or similar functional excipients.
    Type: Application
    Filed: November 2, 2016
    Publication date: May 4, 2017
    Inventors: Dave A. MILLER, Jason T. McCONVILLE, James W. McGINITY, Robert O. WILLIAMS, III
  • Publication number: 20170027911
    Abstract: The disclosure provides for improved pharmaceutical compositions containing deferasirox (DFX) and methods of manufacturing the same. In particular, the compositions are prepared using thermokinetic compounding and provide improved properties as well as more efficient methods of manufacture.
    Type: Application
    Filed: June 17, 2016
    Publication date: February 2, 2017
    Applicant: Dispersol Technologies, LLC
    Inventors: Dave A. MILLER, Justin M. KEEN, Sandra U. KUCERA
  • Patent number: 9504658
    Abstract: A hot-melt extruded composition having finely divided drug-containing particles dispersed within a polymeric and/or lipophyllic carrier matrix is provided. The carrier softens or melts during hot-melt extrusion but it does not dissolve the drug-containing particles during extrusion. As a result, a majority or at least 90% wt. of the drug-containing particles in the extrudate are deaggregated during extrusion into essentially primary crystalline and/or amorphous particles. PEO is a suitable carrier material for drugs insoluble in the solid state in this carrier. Various functional excipients can be included in the carrier system to stabilize the particle size and physical state of the drug substance in either a crystalline and/or amorphous state. The carrier system is comprised of at least one thermal binder, and may also contain various functional excipients, such as: super-disintegrants, antioxidants, surfactants, wetting agents, stabilizing agents, retardants, or similar functional excipients.
    Type: Grant
    Filed: November 9, 2005
    Date of Patent: November 29, 2016
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Dave A. Miller, Jason T. McConville, James W. McGinity, Robert O. Williams, III
  • Publication number: 20160250230
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Application
    Filed: May 13, 2016
    Publication date: September 1, 2016
    Applicants: BOARD OF REGENTS, THE UNIVERISTY OF TEXAS SYSTEM, DISPERSOL TECHNOLOGIES, LLC
    Inventors: Chris BROUGH, James W. MCGINITY, Dave A. MILLER, James C. DINUNZIO, Robert O. WILLIAMS, III
  • Patent number: 9339440
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: May 17, 2016
    Assignees: Board of Regents, the University of Texas System, DisperSol Technologies, LLC
    Inventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
  • Publication number: 20140039031
    Abstract: The present disclosure is directed to compositions and methods for formulating a pharmaceutical dosage form by forming a composition comprising acetyl-11-keto-?-boswellic acid, diindolylmethane, or curcumin with one or more pharmaceutically acceptable excipients for enhanced solubility to increase bioavailability and improve therapeutic efficacy. The composition can be processed by thermo-kinetic compounding along with conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Application
    Filed: February 23, 2012
    Publication date: February 6, 2014
    Applicants: Dispersol Technologies. LLC, Board of Regents, The University of Texas System
    Inventors: Chris Brough, Robert O. Williams, III, James W. McGinity, Dave A. Miller, Justin Hughey, Ryan Bennett
  • Publication number: 20130303630
    Abstract: Compositions and methods for making a pharmaceutical dosage form include making a pharmaceutical composition that includes one or more active pharmaceutical ingredients (API) with one or more pharmaceutically acceptable excipients by thermokinetic compounding into a composite. Compositions and methods of preprocessing a composite comprising one or more APIs with one or more excipients include thermokinetic compounding, comprising thermokinetic processing the APIs with the excipients into a composite, wherein the composite can be further processed by conventional methods known in the art, such as hot melt extrusion, melt granulation, compression molding, tablet compression, capsule filling, film-coating, or injection molding.
    Type: Application
    Filed: July 15, 2013
    Publication date: November 14, 2013
    Inventors: Chris Brough, James W. McGinity, Dave A. Miller, James C. DiNunzio, Robert O. Williams, III
  • Patent number: D701011
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: March 11, 2014
    Assignee: BISSELL Homecare, Inc.
    Inventors: Dave Miller, Christopher John Reinke
  • Patent number: D800464
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: October 24, 2017
    Inventors: Ron Larabie, Dave Miller