Patents by Inventor Dave Pai

Dave Pai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF DEK PROTEIN AND RELATED METHODS
    Publication number: 20200181620
    Abstract: The present invention provides methods of treatment using inhibitors of DEK protein and DEK activity. Such methods include, but are not limited to, methods of preventing, treating, and/or ameliorating inflammatory diseases, infections, autoimmune diseases, malignant diseases, and other diseases or conditions in which DEK has been implicated. Such inhibitors of DEK protein include, but are not limited to, pharmaceutical compositions including single stranded DNA or RNA aptamers capable of binding to DEK. In some embodiments, such aptamers are useful for diagnosing DEK related diseases or conditions. Related kits and compositions are further provided.
    Type: Application
    Filed: February 11, 2020
    Publication date: June 11, 2020
    Inventors: David Markovitz, Nirit Mor-Vaknin, Maureen Legendre, David Engelke, Kristine Benford, Dave Pai
  • INHIBITORS OF DEK PROTEIN AND RELATED METHODS
    Publication number: 20190071675
    Abstract: The present invention provides methods of treatment using inhibitors of DEK protein and DEK activity. Such methods include, but are not limited to, methods of preventing, treating, and/or ameliorating inflammatory diseases, infections, autoimmune diseases, malignant diseases, and other diseases or conditions in which DEK has been implicated. Such inhibitors of DEK protein include, but are not limited to, pharmaceutical compositions including single stranded DNA or RNA aptamers capable of binding to DEK. In some embodiments, such aptamers are useful for diagnosing DEK related diseases or conditions. Related kits and compositions are further provided.
    Type: Application
    Filed: November 15, 2018
    Publication date: March 7, 2019
    Inventors: David Markovitz, Nirit Mor-Vaknin, Maureen Legendre, David Engelke, Kristine Benford, Dave Pai
  • Inhibitors of DEK protein and related methods
    Patent number: 10138486
    Abstract: The present invention provides methods of treatment using inhibitors of DEK protein and DEK activity. Such methods include, but are not limited to, methods of preventing, treating, and/or ameliorating inflammatory diseases, infections, autoimmune diseases, malignant diseases, and other diseases or conditions in which DEK has been implicated. Such inhibitors of DEK protein include, but are not limited to, pharmaceutical compositions including single stranded DNA or RNA aptamers capable of binding to DEK. In some embodiments, such aptamers are useful for diagnosing DEK related diseases or conditions. Related kits and compositions are further provided.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: November 27, 2018
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: David Markovitz, Nirit Mor-Vaknin, Maureen Legendre, David Engelke, Kristine Benford, Dave Pai