Abstract: Techniques and systems for testing, evaluating and/or otherwise assessing the operation of vehicles are discussed herein. Some aspects relate to a system and method which may receive, at a first computer system, vehicle data derived from a vehicle data logging system, and may receive a playback time associated with a portion of the vehicle data. A sharable data structure may be generated which identifies the vehicle data and the playback time. The sharable data structure may be transmitted to a second computer system, wherein the sharable data structure allows the second computer system to retrieve the vehicle data.

Abstract: Compliance inspection system and method. The compliance inspection system includes an interface for at least communicating an inspection assignment to an inspector, wherein the inspection assignment includes an inspection location indicting where an inspection is to occur and for receiving location data related to the inspector. The compliance inspection system also includes a processor executing instructions stored on a memory to analyze the received location data related to the inspector, verify the inspector is at the inspection location based on the analysis of the received location data, and receive inspection documentation related to the inspection from the inspector.

Abstract: A wafer shape metrology system includes a wafer shape metrology sub-system configured to perform one or more stress-free shape measurements on a first wafer, a second wafer, and a post-bonding pair of the first and second wafers. The wafer shape metrology system includes a controller communicatively coupled to the wafer shape metrology sub-system. The controller is configured to receive stress-free shape measurements from the wafer shape sub-system; predict overlay between one or more features on the first wafer and the second wafer based on the stress-free shape measurements of the first wafer, the second wafer, and the post-bonding pair of the first wafer and the second wafer; and provide a feedback adjustment to one or more process tools based on the predicted overlay. Additionally, feedforward and feedback adjustments may be provided to one or more process tools.

Abstract: A method of obtaining a clinical assessment of a user of a user device may include obtaining, by the user device and from a hand-held diagnostic device configured to communicate with the user device, first diagnostic information of the user obtained by one or more sensors of the hand-held diagnostic device; obtaining, by the user device, second diagnostic information based on a user input of the second diagnostic information via the user device; obtaining, by the user device and using an artificial intelligence (AI) model, the clinical assessment based on the first diagnostic information and the second diagnostic information; and displaying, by the user device, the clinical assessment to permit the user to visualize the clinical assessment.

Abstract: An information technology (IT) network includes configuration items (CIs) that may constantly change, where the CIs describe hardware components or software components that are configured to operate on the IT network. Machine learning techniques can be employed determine whether a CI has been changed (e.g., added, updated, or removed) in the IT network. For example, a software code or a log message associated with a CI can be analyzed to determine whether the CI is a newly added or updated within the IT network.

Abstract: A method includes assessing a semantic-based query for a user that includes user goals and assessing probability values and first goal probability values, both of which are associated with active digital actions. The method includes generating a decision engine to determine a user friction value and second goal probability values associated with the user goals using the first goal probability values and the probability values. Further, the method includes determining the user friction value and the second goal probability values using the first goal probability values and the probability values. Moreover, the method includes determining a plan of digital actions based on the user friction value, the second goal probability values, and the user goals. Furthermore, the method includes, in response to determining the user friction value exceeds a predetermined threshold, generating a query to adjust the active digital actions based on the semantic-based query for the user.

Abstract: A method includes receiving, with a processor in communication with a first exercise machine, a first request for an exercise class, the first request being provided by a first user of the first exercise machine. The method also includes providing a video file associated with the exercise class to the first exercise machine, providing a notification to a second user indicating that the first user has chosen to participate in the exercise class, and receiving a second request for the exercise class provided by the second user. The method further includes providing the video file to a second exercise machine of the second user via the network. In such a method, display of the video file via a display of the second exercise machine is synchronized with display of the video file via a display of the first exercise machine.

Abstract: Compliance inspection system and method. The compliance inspection system includes an interface for at least communicating an inspection assignment to an inspector, wherein the inspection assignment includes an inspection location indicting where an inspection is to occur and for receiving location data related to the inspector. The compliance inspection system also includes a processor executing instructions stored on a memory to analyze the received location data related to the inspector, verify the inspector is at the inspection location based on the analysis of the received location data, and receive inspection documentation related to the inspection from the inspector.

Abstract: A macromolecule includes i) a dendrimer comprising a core and at least one generation of building units, the outermost generation of building units having surface amino groups wherein at least two different terminal groups are covalently attached to the surface amino groups of the dendrimer, ii) a first terminal group which is a residue of a pharmaceutically active agent comprising a hydroxyl group, and iii) a second terminal group which is a pharmacokinetic modifying agent. The pharmaceutically active agent is cabazitaxel. The first terminal group is covalently attached to the surface amino group of the dendrimer through a diacid linker, the diacid linker comprising an alkyl chain interrupted by one or more oxygen, sulfur or nitrogen atoms, or a pharmaceutically acceptable salt thereof.

Abstract: An aspect includes a computer-implemented method that predicts a proposed region of interest in an image from a video of a surgical procedure based on one or more contextual targets. An image adjustment is synthesized based on the proposed region of interest and the image. A modified visualization of the surgical procedure is generated by incorporating the image adjustment in a real-time output of the video of the surgical procedure. The video of the surgical procedure is displayed with the modified visualization.

Abstract: Provided herein is dendrimer-targeting agent conjugate comprising: (a) a dendrimer comprising i) a core unit (C); and ii) building units (BU), wherein the dendrimer has from two to six generations of building units; and wherein the core unit is covalently attached to at least two building units; and the dendrimer further comprising: b) a targeting agent which is covalently linked to the dendrimer by a spacer group; c) one or more first terminal groups attached to an outermost building unit of the dendrimer, wherein the first terminal group comprises a complexation group for complexing a radionuclide; and d) one or more second terminal groups attached to an outermost building unit of the dendrimer, wherein the second terminal group comprises a pharmacokinetic-modifying moiety, or a salt thereof.

Abstract: An interactive system may be implemented in part by an audio device located within a user environment, which may accept speech commands from a user and may also interact with the user by means of generated speech. In order to improve performance of the interactive system, a user may use a separate device, such as a personal computer or mobile device, to access a graphical user interface that lists details of historical speech interactions. The graphical user interface may be configured to allow the user to provide feedback and/or corrections regarding the details of specific interactions.

Abstract: An interactive system may be implemented in part by an audio device located within a user environment, which may accept speech commands from a user and may also interact with the user by means of generated speech. In order to improve performance of the interactive system, a user may use a separate device, such as a personal computer or mobile device, to access a graphical user interface that lists details of historical speech interactions. The graphical user interface may be configured to allow the user to provide feedback and/or corrections regarding the details of specific interactions.

Abstract: Disclosed are dendrimers of formula (I): and pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions comprising the dendrimer of formula (I) and methods of using the same for treating cancer.

Abstract: A wafer shape metrology system includes a wafer shape metrology sub-system configured to perform one or more stress-free shape measurements on a first wafer, a second wafer, and a post-bonding pair of the first and second wafers. The wafer shape metrology system includes a controller communicatively coupled to the wafer shape metrology sub-system. The controller is configured to receive stress-free shape measurements from the wafer shape sub-system; predict overlay between one or more features on the first wafer and the second wafer based on the stress-free shape measurements of the first wafer, the second wafer, and the post-bonding pair of the first wafer and the second wafer; and provide a feedback adjustment to one or more process tools based on the predicted overlay. Additionally, feedforward and feedback adjustments may be provided to one or more process tools.

Abstract: Disclosed embodiments are directed to quad track skid-steer loaders and power machines having a frame, a cab, and a lift arm assembly pivotally coupled to the frame rearward of at least a portion of the cab and extending forward of the frame. A first axle assembly and a second axle assembly on a first side of the frame mount first and second track assemblies. A third axle assembly and a fourth axle assembly on a second side of the frame mount third and fourth track assemblies. A first drive motor rotates the first and second axles to drive the first and second track assemblies and a second drive motor rotates the third and fourth axles to drive the third and fourth track assemblies.

Abstract: The invention generally relates to products for use in the treatment and/or prevention of Pulmonary Arterial Hypertension (PAH). More specifically, the invention relates to translocator protein (TSPO) binding members which treat or prevent pulmonary endothelial cell dysfunction, and the use of such TSPO binding members for use in the treatment and/or prevention of PAH [FIG. 1].

Abstract: The present disclosure provides peptoid-based chelating ligands, corresponding cyclic peptoids, and methods of making thereof. Functional groups may be tailored for high metal binding affinity and selectivity. The side chains of a cyclic peptoid according to the present disclosure may be selected based on, for example, high affinity for actinide or other metal ions, selectivity for actinide or other metal ions, the ability to recover a metal once it is bound to the peptoid, and whether the overall peptoid should be hydrophobic or hydrophilic. Unlike siderophores, peptoid-based chelating ligands of the present disclosure are not readily hydrolyzed under physiological conditions. Therefore, peptoid-based chelating ligands may be, for example, used to treat actinide (e.g., iron and lead) poisoning in vivo. Moreover, peptoid-based chelating ligands of the present disclosure may be used for medical imaging, chelation therapy, drug delivery, and separation technologies, for example.

Abstract: An information technology (IT) network includes configuration items (CIs) that may constantly change, where the CIs describe hardware components or software components that are configured to operate on the IT network. Machine learning techniques can be employed determine whether a CI has been changed (e.g., added, updated, or removed) in the IT network. For example, a software code or a log message associated with a CI can be analyzed to determine whether the CI is a newly added or updated within the IT network.