Patents by Inventor David A. Adler

David A. Adler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20060129529
    Abstract: A system, method, and associated computer product improve the search of multidimensional databases. The present system determines a near-optimal grid index that is used to locate a geometric shape in a spatial database. More particularly, the present system improves the technique of sampling data for defining the grid cell size in a grid for a given data set, minimizing the number times the data set needs to be sampled, thereby reducing the time to compute the cost of alternative grid index parameters.
    Type: Application
    Filed: December 7, 2004
    Publication date: June 15, 2006
    Inventor: David Adler
  • Publication number: 20060041551
    Abstract: Techniques of querying an index of first objects comprised of a plurality of index entries and a pool of second objects are provided. The techniques include evaluating the index of the first objects to produce a group of one or more possible candidates based on whether one or more index entries of the first objects satisfy a query, adding second objects from the pool to said group of possible candidates to produce an interim group of possible candidates, filtering the interim group of possible candidates by comparing approximations of the candidates of the interim group with the query to produce filtered candidate objects, and determining if the filtered candidate objects satisfy the query by comparing the first and second objects corresponding to the filtered candidate objects with the query.
    Type: Application
    Filed: October 20, 2005
    Publication date: February 23, 2006
    Inventors: David Adler, Knut Stolze
  • Publication number: 20060036628
    Abstract: The number of index entries in a grid index for indexing geometric shapes is reduced by establishing a pool storage area for geometric shapes, selecting a threshold number of grid cells which a geometric shape may overlap, storing the shape in the grid index if a geometric shape overlaps a number of grid cells not exceeding the threshold number, and storing the shape in the pool storage area if the geometric shape overlaps a number of grid cells which exceeds the threshold number.
    Type: Application
    Filed: October 20, 2005
    Publication date: February 16, 2006
    Inventors: David Adler, Knut Stolze
  • Patent number: 6979819
    Abstract: A method of inspecting and imaging substrates with an electron beam. The method can include a illuminating the substrate with a photon beam to cause photoemission of electrons. A low energy electron beam can be used to prevent or reduce positive charging of the substrate. Reflected electrons and/or emitted photoelectrons can be imaged to review or inspect the substrate.
    Type: Grant
    Filed: December 14, 2001
    Date of Patent: December 27, 2005
    Assignee: KLA-Tencor Technologies Corporation
    Inventors: David Adler, Matthew Marcus
  • Publication number: 20050198008
    Abstract: Provided is a technique for index exploitation. A spatial region query referencing a spatial region is received. The spatial region is divided into intervals. Search ranges are generated for each interval. An index scan is performed for each interval.
    Type: Application
    Filed: March 2, 2004
    Publication date: September 8, 2005
    Inventor: David Adler
  • Publication number: 20050144813
    Abstract: A device and method is provided for rescuing a person trapped in engulfing material at an engulfment site. A reduction tool is used to loosen the engulfing material in order to free or facilitate freeing a buried or partially buried victim. The loosened engulfing material is subsequently removed from the engulfment site by vacuum excavation. Shoring equipment may be used to stabilize the excavation site prior to commencement of soil reduction and soil removal procedures. The excavation site may include a sump area to receive loosened engulfing material discharged by the reduction tool from the excavation site. The loosened engulfing material in the sump area may also be removed with vacuum excavation techniques.
    Type: Application
    Filed: February 22, 2005
    Publication date: July 7, 2005
    Inventor: David Adler
  • Publication number: 20050139767
    Abstract: Disclosed is a method of inspecting a sample. The sample is scanned in a first direction with at least one particle beam. The sample is scanned in a second direction with at least one particle beam. The second direction is at an angle to the first direction. The number of defects per an area of the sample are found as a result of the first scan, and the position of one or more of the found defects is determined from the second scan. In a specific embodiment, the sample includes a test structure having a plurality of test elements thereon. A first portion of the test elements is exposed to the beam during the first scan to identify test elements having defects, and a second portion of the test elements is exposed during the second scan to isolate and characterize the defect.
    Type: Application
    Filed: February 15, 2005
    Publication date: June 30, 2005
    Inventors: Gustavo Pinto, Brian Leslie, David Adler, Akella Satya, Robert Long, David Walker
  • Publication number: 20050065322
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig63, a novel secreted salivary protein. The polypeptides, and polynucleotides encoding them, may exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The polynucleotides encoding zsig63, are located on chromosome 4, and can be used to identify a region of the genome associated with human disease states. The present invention also includes antibodies to the zsig63 polypeptides.
    Type: Application
    Filed: October 20, 2004
    Publication date: March 24, 2005
    Inventors: David Adler, Paul Sheppard
  • Patent number: 6828419
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig63, a novel secreted salivary protein. The polypeptides, and polynucleotides encoding them, may exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The polynucleotides encoding zsig63, are located on chromosome 4, and can be used to identify a region of the genome associated with human disease states. The present invention also includes antibodies to the zsig63 polypeptides.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: December 7, 2004
    Assignee: ZymoGenetics, Inc.
    Inventors: David A. Adler, Paul O. Sheppard
  • Publication number: 20040129602
    Abstract: A foldable carrying case with a frame. The frame is typically made from metal tubing and designed to accommodate a typically rectangular carrying case. The rectangular carrying case has walls that are attached to each other along common edges and can fold apart as to be flat laying. The carrying case may be attached to the frame and the frame attached to a person so that the person can carry the foldable carrying case as if it were a backpack.
    Type: Application
    Filed: November 7, 2003
    Publication date: July 8, 2004
    Applicant: Andrew David Adler
    Inventors: Rachel Theora Sapyta, Andrew David Adler
  • Publication number: 20030166913
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zamp1, a novel member of the &bgr;-defensin family. The polypeptides, and polynucleotides encoding them, exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The present invention also includes antibodies to the zamp1 polypeptides.
    Type: Application
    Filed: April 7, 2003
    Publication date: September 4, 2003
    Applicant: ZymoGenetics, Inc.
    Inventors: David A. Adler, James L. Holloway, Nand Baindur, Stephanie Beigel-Orme, Paul O. Sheppard
  • Publication number: 20030166912
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zamp1, a novel member of the &bgr;-defensin family. The polypeptides, and polynucleotides encoding them, exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The present invention also includes antibodies to the zamp1 polypeptides.
    Type: Application
    Filed: April 7, 2003
    Publication date: September 4, 2003
    Applicant: ZymoGenetics, Inc.
    Inventors: David A. Adler, James L. Holloway, Nand Baindur, Stephanie Beigel-Orme, Paul O. Sheppard
  • Publication number: 20030157638
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zamp1, a novel member of the &bgr;-defensin family. The polypeptides, and polynucleotides encoding them, exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The present invention also includes antibodies to the zamp1 polypeptides.
    Type: Application
    Filed: October 15, 2002
    Publication date: August 21, 2003
    Inventors: David A. Adler, James L. Holloway, Nand Baindur, Stephanie Beigel-Orme, Paul O. Sheppard
  • Publication number: 20030143671
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zamp1, a novel member of the &bgr;-defensin family. The polypeptides, and polynucleotides encoding them, exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The present invention also includes antibodies to the zamp1 polypeptides.
    Type: Application
    Filed: March 5, 2002
    Publication date: July 31, 2003
    Inventors: David A. Adler, James L. Holloway, Nand Baindur, Stephanie Beigel-Orme, Paul O. Sheppard
  • Patent number: 6576755
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zamp1, a novel member of the &bgr;-defensin family. The polypeptides, and polynucleotides encoding them, exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The present invention also includes antibodies to the zamp1 polypeptides.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: June 10, 2003
    Assignee: ZymoGenetics, Inc.
    Inventors: David A. Adler, James L. Holloway, Nand Baindur, Stephanie Beigel-Orme, Paul O. Sheppard
  • Publication number: 20030104398
    Abstract: Novel soluble, and membrane bound, Beta1,3 galactosyltransferase polypeptides, polynucleotides encoding the polypeptides, antibodies and related compositions and methods are disclosed. The polypeptides may be used for detecting anti-complementary molecules, agonists and antagonists. The polypeptides, polynucleotides and antibodies may also be used in methods that modulate cell-cell interactions, and glycoprotein and glycolipid modifications.
    Type: Application
    Filed: November 2, 2001
    Publication date: June 5, 2003
    Inventors: David A. Adler, James L. Holloway, Gayle Yamamoto
  • Publication number: 20020173027
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig63, a novel secreted salivary protein. The polypeptides, and polynucleotides encoding them, may exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The polynucleotides encoding zsig63, are located on chromosome 4, and can be used to identify a region of the genome associated with human disease states. The present invention also includes antibodies to the zsig63 polypeptides.
    Type: Application
    Filed: August 3, 2001
    Publication date: November 21, 2002
    Inventors: David A. Adler, Paul O. Sheppard
  • Publication number: 20020161534
    Abstract: A method and apparatus for inspection and review of defects is disclosed wherein data gathering is improved. In one embodiment, multiple or segmented detectors are used in a particle beam system.
    Type: Application
    Filed: December 14, 2001
    Publication date: October 31, 2002
    Applicant: KLA-Tencor Corporation
    Inventors: David Adler, Kirk Bertsche, Mark McCord, Stuart Friedman
  • Publication number: 20020090677
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig63, a novel secreted salivary protein. The polypeptides, and polynucleotides encoding them, may exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The polynucleotides encoding zsig63, are located on chromosome 4, and can be used to identify a region of the genome associated with human disease states. The present invention also includes antibodies to the zsig63 polypeptides.
    Type: Application
    Filed: August 3, 2001
    Publication date: July 11, 2002
    Inventors: David A. Adler, Paul O. Sheppard
  • Publication number: 20020086988
    Abstract: The present invention provides to polynucleotides and secreted proteins encoded by the polynucleotides. The proteins include a variety of fusion proteins, including fusions comprising a signal peptide selected from the group consisting of signal peptides shown in SEQ ID NO:M, wherein M is an even integer from 2 to 122, operably linked to a second polypeptide. The invention further provides therapeutic and diagnostic methods utilizing the polynucleotides, polypeptides, and antagonists of the polypeptides.
    Type: Application
    Filed: March 5, 2001
    Publication date: July 4, 2002
    Inventors: Darrell C. Conklin, Scott R. Presnell, David A. Adler