Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating, preventing, or reducing the recurrence of a stricture and/or cancer, or for treating benign prostatic hyperplasia (BPH), in a non-vascular body lumen and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent. In some embodiments, the balloon catheter includes a length-control mechanism which stretches and elongates the balloon when it is in a deflated state, giving the balloon a smaller cross-sectional deflated profile for tracking through the body lumen and for removal after treatment.

Abstract: Various embodiments disclosed relate to drug-coated balloon catheters for treating strictures in body lumens and methods of using the same. A drug-coated balloon catheter for delivering a therapeutic agent to a target site of a body lumen stricture includes an elongated balloon having a main diameter. The balloon catheter includes a coating layer overlying an exterior surface of the balloon. The coating layer includes one or more water-soluble additives and an initial drug load of a therapeutic agent.

Abstract: Embodiments of the present invention provide methods for the treatment or prevention of infection-related immune conditions using compositions comprising IgM.

Abstract: At least some embodiments of the technology are directed to an automated slide processing apparatus configured to apply at least one reagent to a specimen carried by a microscope slide. The slide processing station can include a support element with a support surface, at least one vacuum port, and a sealing member having a non-round shape. In an uncompressed state, the sealing member can extend upwardly beyond the support surface. In a compressed state, the sealing member can be configured to maintain an airtight seal with a backside of the microscope slide as the microscope slide is pulled against the support surface by a vacuum drawn via the at least one vacuum port.

Abstract: Devices and methods for administering a medication in fluid form, the systems and methods including a basal flow path and a bolus flow path in parallel to the basal flow path. The bolus flow path includes a combined piston pump and rotatable valve. The piston pump is configured to prevent partial dosing of a bolus dose.

Abstract: The present disclosure provides stable inoculant compositions and methods for enhancing the survival and/or stability of microorganisms in an inoculant composition. In some embodiments, the microorganisms in an inoculant compositions are stabilized by the presence of one or more maltodextrins having a dextrose equivalent value of about 15 to about 20.

Abstract: Provided are methods, systems, and devices for generating semantic objects and an output based on the detection or recognition of the state of an environment that includes objects. State data, based in part on sensor output, can be received from one or more sensors that detect a state of an environment including objects. Based in part on the state data, semantic objects are generated. The semantic objects can correspond to the objects and include a set of attributes. Based in part on the set of attributes of the semantic objects, one or more operating modes, associated with the semantic objects can be determined. Based in part on the one or more operating modes, object outputs associated with the semantic objects can be generated. The object outputs can include one or more visual indications or one or more audio indications.

Abstract: A cam for an archery bow having flat segmented power cable tracks or journals. The cam preferably includes five stacked journals sharing a common axis. The middle journal receivable for a bowstring with opposing mirrored and segmented cable journals above and below the bowstring journal plane. Alternately, the cam having three stacked journals; a bowstring journal and two segmented cable journals. A bowstring and cable(s) interact with the cam(s) and other components to fire a projectile, such as an arrow.

Abstract: A case includes a case body configured to equip a mobile electronic device. The case includes an actuator, and the mobile electronic device includes a physical button. The case further includes an actuator switch coupled to the case body and movable between at least a first unengaged position and a second engaged position, where the switch is connected to an engagement member. The engagement member activates a corresponding physical button of the mobile electronic device when the mobile electronic device is equipped with the case and the actuator switch is moved to the second position. The engagement member is configured to not activate the mobile electronic device button when the actuator is moved to the first position.

Abstract: A rope-cocker rope retainment assembly for a crossbow that operably and selectively retains a rope with the crossbow frame, while cocking the crossbow.

Abstract: A projectile launching device having a bowstring carrier operably coupled with a bowstring carrier traverse assembly. The bowstring carrier traverse assembly having a motor operable with a spool and a connecting component, wherein when the bowstring is not retaining a bowstring and the bowstring carrier is in the cocked position, the traverse assembly selectively returns the bowstring carrier to the at-rest position.

Abstract: A crossbow having a crossbow frame and a bow assembly. The bow riser of the bow assembly having a launch deck surface and a bore below the launch deck surface. The crossbow frame having a launch deck surface and a coupling rod below the launch deck surface. The coupling rod is sized to cooperate with the bore, and the coupling rod is axial to and concentric with the bore. The bow riser is axially coupled to the crossbow frame by the coupling rod, the bow assembly has a first position for shooting a projectile and a second position for storage or transportation. Any suitable device may be used to lock the angular orientation between the bow assembly and the crossbow frame, such as pins, plungers, springs, detents and the like in the first and second positions.

Abstract: The crossbow preferably includes a rail, a riser, two energy storing components, (such as two limbs), two cams, and a bowstring harness. The bowstring harness is operably coupled with the cams. A halo-type cable hub is operably coupled with the bow riser or rail. The bowstring harness is operably coupled with the halo-type cable hub. The halo-type cable hub has a first side and a second side, an upper portion and a lower portion, and is of a material that is stronger than the material of the riser and rail. The first and seconds sides are preferably built as mirror images of each other at a centerline of the rail.

Abstract: The crossbow preferably includes a rail, a riser, two energy storing components, (such as two limbs), two cams, and a bowstring harness. The bowstring harness is operably coupled with the cams. A halo-type cable hub is operably coupled with the bow riser or rail. The bowstring harness is operably coupled with the halo-type cable hub. The halo-type cable hub has a first side and a second side, an upper portion and a lower portion, and is of a material that is stronger than the material of the riser and rail. The first and seconds sides are preferably built as mirror images of each other at a centerline of the rail.

Abstract: An arrow head cluster is created utilizing an injection mold. An upper cluster cavity is formed in an upper die member and a lower cluster cavity is created in a lower die member. The upper and lower cluster cavities, when joined create a cluster cavity. The cluster cavity is used to create the arrow head cluster, after molten material is injected into the injection mold. The cluster cavity includes a plurality of chambers for creating a plurality of arrow heads. The plurality of chambers are connected to each other with a plurality of flow channels and a support frame. The injected material includes metals, ceramic and plastic. The materials are injected into the cluster cavity through the plurality of flow channels. The plurality of flow channels allow the material to flow evenly through the plurality of cluster cavities.

Abstract: A molded arrow assembly preferably includes an insert and an outsert for an arrow or an insert/outsert assembly. The molded arrow assembly may include an insert having a cylindrical body with a first end and a second end. The second end may be dimensioned to fit within a bore of an arrow shaft. The first end may terminate in a prong containing male threads. The insert/outsert assembly may also include an outsert having a cylindrical wall with an arrow shaft end and an arrowhead end. The cylindrical wall may also include a center bore extending between the arrow shaft end and the arrowhead end. The center bore may contain a threaded region containing female threads. The threaded region may be located intermediate of the arrowhead end and the arrow shaft end and may extend between a top shoulder and a bottom shoulder.

Abstract: An arrow head cluster is created utilizing an injection mold. An upper cluster cavity is formed in an upper die member and a lower cluster cavity is created in a lower die member. The upper and lower cluster cavities, when joined create a cluster cavity. The cluster cavity is used to create the arrow head cluster, after molten material is injected into the injection mold. The cluster cavity includes a plurality of chambers for creating a plurality of arrow heads. The plurality of chambers are connected to each other with a plurality of flow channels and a support frame. The injected material includes metals, ceramic and plastic. The materials are injected into the cluster cavity through the plurality of flow channels. The plurality of flow channels allow the material to flow evenly through the plurality of cluster cavities.