Patents by Inventor David A. Blain

David A. Blain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260085252
    Abstract: Provided are paper machine lubricating compositions and methods of operating a paper machine with said paper machine lubricating compositions, where the paper machine lubricating compositions comprise about 20 wt % to about 80 wt % of a first oil basestock, wherein the first oil basestock comprises an API group II extra heavy neutral basestock, and about 2 wt % to about 40 wt % of a second oil basestock, wherein the second oil basestock comprises an API group I, an API group II, an API group IV basestock, or any combination thereof, where the API group II extra heavy neutral basestock has: a kinematic viscosity (ASTM D445, 40° C.) of 320 cSt to 520 cSt, a kinematic viscosity (ASTM D445, 100° C.) of 22 cSt to 36 cSt, a viscosity index (ASTM D2270) of 80 to 119, a pour point (ASTM D97) of ?6° C. or less, and a saturate content (ASTM D7419) of 90 wt % or greater; and wherein the second oil basestock has a kinematic viscosity (ASTM D445, 40° C.) of 3 cSt to 50 cSt.
    Type: Application
    Filed: September 24, 2025
    Publication date: March 26, 2026
    Applicant: EXXONMOBIL TECHNOLOGY AND ENGINEERING COMPANY
    Inventors: Reda K. FAWZY, David A. BLAIN, Michael L. BLUMENFELD, Hong CHENG, Lin WANG
  • Publication number: 20210171631
    Abstract: The present invention relates to the identification of fibrinogen like protein 1 (FGL1) as a prognostic biomarker for responsiveness to an immune checkpoint inhibitor in a cancer patient. More specifically it relates to methods of treating cancer in a human patient comprising administering an immune checkpoint inhibitory antibody specifically inhibiting the interaction of fibrinogen-like protein 1 (FGL1) with lymphocyte-activation gene 3 protein (LAG3), wherein the cancer is an FGL1 expressing cancer. Further, the invention relates to methods for assessing susceptibility or predicting the responsiveness to the treatment with an immune checkpoint inhibitory antibody specifically inhibiting the interaction of FGL1 with LAG3 in a cancer patient, comprising detecting FGL1 expression in a sample from said patient and to a kit for selecting a cancer patient that would benefit from an immune checkpoint inhibitory antibody specifically inhibiting the interaction of FGL1 with LAG3.
    Type: Application
    Filed: June 10, 2019
    Publication date: June 10, 2021
    Inventors: Lieping CHEN, Jun WANG, David A. BLAIN, Timothy ZHENG
  • Patent number: 10676689
    Abstract: Grease compositions are provided that can have one or more unexpectedly beneficial low temperature properties even though the grease compositions are formed from lower value components that traditional low temperature greases. The unexpectedly beneficial low temperature properties can be achieved in part by grease compositions that include a naphthenic base stock having a viscosity index of roughly 120 or less and/or a pour point of ?20° C. or more while having a naphthenes content of 60 wt % or more. In some aspects, the naphthenic base stock can have an aromatics content of 20 wt % or less.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: June 9, 2020
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Sarvesh K. Agrawal, James E. Spagnoli, David A. Blain
  • Publication number: 20190203150
    Abstract: Grease compositions are provided that can have one or more unexpectedly beneficial low temperature properties even though the grease compositions are formed from lower value components that traditional low temperature greases. The unexpectedly beneficial low temperature properties can be achieved in part by grease compositions that include a naphthenic base stock having a viscosity index of roughly 120 or less and/or a pour point of ?20° C. or more while having a naphthenes content of 60 wt % or more. In some aspects, the naphthenic base stock can have an aromatics content of 20 wt % or less.
    Type: Application
    Filed: December 11, 2018
    Publication date: July 4, 2019
    Inventors: Sarvesh K. AGRAWAL, James E. SPAGNOLI, David A. BLAIN
  • Patent number: 10316265
    Abstract: A composition including one or more diester compounds represented by the formula as defined herein. The composition has a viscosity (Kv100) from about 1 cSt to about 10 cSt at 100° C. as determined by ASTM D445, a viscosity index (VI) from about ?100 to about 300 as determined by ASTM D2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D5800. A process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the composition.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: June 11, 2019
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Man Kit Ng, Halou Oumar-Mahamat, Hong Cheng, David A. Blain
  • Publication number: 20190085256
    Abstract: The present disclosure provides a lubricating composition that includes at least one lubricating base oil, an effective amount of at least one overbased detergent; and an effective amount of at least one thermally stable zinc dialkyl dithiophosphate. The disclosure further provides methods of making and using the same.
    Type: Application
    Filed: September 6, 2018
    Publication date: March 21, 2019
    Inventors: Rajeev KUMAR, Kevin J. BUZDYGON, Kathleen K. COOPER, David A. BLAIN, David G.L. HOLT
  • Patent number: 10077409
    Abstract: A lubricating oil base stock including one or more monoesters represented by the formula (I), (II), (III) and (IV) as defined herein. The lubricating oil base stock has a high temperature high shear (HTHS) viscosity of less than about 1.7 cP as determined by ASTM D4683, and a Noack volatility from about 15 to about 90 percent as determined by ASTM D5800. A lubricating oil containing the lubricating oil base stock including one or more monoesters represented by the formula (I), (II), (III) and (IV) as defined herein. A method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the lubricating oil base stock including one or more monoesters represented by the formula (I), (II), (III) and (IV) as defined herein.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: September 18, 2018
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Man Kit Ng, Halou Oumar-Mahamat, Hong Cheng, David A. Blain, Kathleen K. Cooper, James T. Carey, Michael R. Douglass, Percy R. Kanga, Abhimanyu O. Patil, Satish Bodige, Kyle G. Lewis, Mark P. Hagemeister
  • Patent number: 9976099
    Abstract: A composition including one or more aromatic alkanoate monoester compounds represented by the formulae (I) and (II) as defined herein. The composition has a viscosity (Kv100) from about 1 cSt to about 10 cSt at 100° C. as determined by ASTM D445, a viscosity index (VI) from about ?100 to about 300 as determined by ASTM D2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D5800. A process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the composition.
    Type: Grant
    Filed: December 20, 2016
    Date of Patent: May 22, 2018
    Assignee: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Man Kit Ng, Halou Oumar-Mahamat, Hong Cheng, David A. Blain
  • Publication number: 20170183596
    Abstract: A composition including one or more aromatic alkanoate monoester compounds represented by the formulae (I) and (II) as defined herein. The composition has a viscosity (Kv100) from about 1 cSt to about 10 cSt at 100° C. as determined by ASTM D445, a viscosity index (VI) from about ?100 to about 300 as determined by ASTM D2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D5800. A process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the composition.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 29, 2017
    Inventors: Man Kit Ng, Halou Oumar-Mahamat, Hong Cheng, David A. Blain
  • Publication number: 20170183597
    Abstract: A composition including one or more diester compounds represented by the formula as defined herein. The composition has a viscosity (Kv100) from about 1 cSt to about 10 cSt at 100° C. as determined by ASTM D445, a viscosity index (VI) from about ?100 to about 300 as determined by ASTM D2270, and a Noack volatility of no greater than 50 percent as determined by ASTM D5800. A process for producing the composition, a lubricating oil base stock and lubricating oil containing the composition, and a method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the composition.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 29, 2017
    Inventors: Man Kit Ng, Halou Oumar-Mahamat, Hong Cheng, David A. Blain
  • Publication number: 20170183595
    Abstract: A lubricating oil base stock including one or more monoesters represented by the formula (I), (II), (III) and (IV) as defined herein. The lubricating oil base stock has a high temperature high shear (HTHS) viscosity of less than about 1.7 cP as determined by ASTM D4683, and a Noack volatility from about 15 to about 90 percent as determined by ASTM D5800. A lubricating oil containing the lubricating oil base stock including one or more monoesters represented by the formula (I), (II), (III) and (IV) as defined herein. A method for improving one or more of thermal and oxidative stability, solubility and dispersancy of polar additives, deposit control and traction control in a lubricating oil by using as the lubricating oil a formulated oil containing the lubricating oil base stock including one or more monoesters represented by the formula (I), (II), (III) and (IV) as defined herein.
    Type: Application
    Filed: December 20, 2016
    Publication date: June 29, 2017
    Inventors: Man Kit Ng, Halou Oumar-Mahamat, Hong Cheng, David A. Blain, Kathleen K. Cooper, James T. Carey, Michael R. Douglass, Percy R. Kanga, Abhimanyu O. Patil, Satish Bodige, Kyle G. Lewis, Mark P. Hagemeister
  • Patent number: 8623796
    Abstract: This invention is directed to a lubricant composition that is comprised of a continuous phase and a discontinuous phase, i.e., a two phase lubricant composition. The continuous phase and the discontinuous phase of the lubricant of this invention are oil or oil type compositions that are essentially insoluble in one another. The lubricant composition is comprised of a continuous phase base oil that is comprised of a low viscosity Group II, III, IV or GTL base stock or a blend of at least two of the Group II, III, IV and GTL base stocks, optionally including a low viscosity Group V base stock, with the continuous phase base oil having, independently, a viscosity of from 1 to 100 cSt at 100° C. The lubricant composition is further comprised of a discontinuous phase that is comprised of an ester composition having a mean average droplet size of from 0.01 microns to 20 microns, in which the ester composition is comprised of an ester compound having no ether linkages.
    Type: Grant
    Filed: May 27, 2011
    Date of Patent: January 7, 2014
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Evelyn N. Drake, Samuel C. Bainbridge, David A. Blain, James T. Carey, Angela S. Galiano-Roth, L. Oscar Farng, Suzzy C. Ho, David K. Prendergast, Martin N. Webster, Margaret M. Wu
  • Patent number: 8569216
    Abstract: A Group IV/Group V lubricating composition providing improved antioxidation performance comprises from 5 wt. % to 40 wt. % of a Group V base oil component, such as alkylated naphthalene, at least 30 wt. % of a Group IV base oil component, such as one or more polyalphaolefin base stocks, and from 0.25 wt. % to 1.5 wt. % of a trithiophosphate-containing compound. The trithiophosphate-containing compound is preferably C30H57O7PS3. The lubricating composition includes not greater than 5 wt. % of a Group I, Group II, or Group III base oil component, and, preferably not greater than 10 ppm heavy metal component. The lubricating composition preferably has a kinematic viscosity of from 20 cSt to 1,000 cSt at 40° C. and a viscosity index (VI) of from 130 to 200.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: October 29, 2013
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: David A. Blain, Liehpao Oscar Farng, Eugenio Sanchez, Michael R. Douglass, Angela S. Galiano-Roth, James T. Carey
  • Publication number: 20120322705
    Abstract: A Group IV/Group V lubricating composition providing improved antioxidation performance comprises from 5 wt. % to 40 wt. % of a Group V base oil component, such as alkylated naphthalene, at least 30 wt. % of a Group IV base oil component, such as one or more polyalphaolefin base stocks, and from 0.25 wt. % to 1.5 wt. % of a trithiophosphate-containing compound. The trithiophosphate-containing compound is preferably C30H57O7PS3. The lubricating composition includes not greater than 5 wt. % of a Group I, Group II, or Group III base oil component, and, preferably not greater than 10 ppm heavy metal component. The lubricating composition preferably has a kinematic viscosity of from 20 cSt to 1,000 cSt at 40° C. and a viscosity index (VI) of from 130 to 200.
    Type: Application
    Filed: June 16, 2011
    Publication date: December 20, 2012
    Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: David A. Blain, Liehpao Oscar Farng, Eugenio Sanchez, Michael R. Douglass, Angela S. Galiano-Roth, James T. Carey
  • Publication number: 20120302473
    Abstract: This invention is directed to a lubricant composition that is comprised of a continuous phase and a discontinuous phase, i.e., a two phase lubricant composition. The continuous phase and the discontinuous phase of the lubricant of this invention are oil or oil type compositions that are essentially insoluble in one another. The lubricant composition is comprised of a continuous phase base oil that is comprised of a low viscosity Group II, III, IV or GTL base stock or a blend of at least two of the Group II, III, IV and GTL base stocks, optionally including a low viscosity Group V base stock, with the continuous phase base oil having, independently, a viscosity of from 1 to 100 cSt at 100° C. The lubricant composition is further comprised of a discontinuous phase that is comprised of an ester composition having a mean average droplet size of from 0.01 microns to 20 microns, in which the ester composition is comprised of an ester compound having no ether linkages.
    Type: Application
    Filed: May 27, 2011
    Publication date: November 29, 2012
    Applicant: EXXONMOBIL RESEARCH AND ENGINEERING COMPANY
    Inventors: Evelyn N. Drake, Samuel C. Bainbridge, David A. Blain, James T. Carey, Angela S. Galiano-Roth, L. Oscar Farng, Suzzy C. Ho, David K. Prendergast, Martin N. Webster, Margaret M. Wu
  • Patent number: 7684933
    Abstract: A method and system to blend components to form a lubricant having a predetermined characteristic. The method includes determining the characteristic from a model that relates that characteristic as a function of the amount of its components and properties of the components. These predetermined characteristics include KV (kinematic viscosities), CCS (cold cranking simulator), HTHS (high temperature, high shear viscosity), Noack Volatility, MRV (mini-rotary viscometer), Brookfield Viscosity, Soot-Dispersancy, Oxidation, Deposit, Wear, Sulfur, Phosphorus, Base Number, Color, Ash Content, Aniline Point, Acid Number, Viscosity Index, Turbidity, Demulsibility, Foam Stability, Acute Toxicity, Biodegradability, Nitrogen, and Detergency.
    Type: Grant
    Filed: November 6, 2007
    Date of Patent: March 23, 2010
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Jason Z. Gao, Peter Calcavecchio, Medi M. Hafez, Joan M. Kaminski, Liehpao Oscar Farng, David A. Blain, Gene Sanchez, Janet L. Lane
  • Publication number: 20080140366
    Abstract: A method to blend components to form a lubricant having a predetermined characteristic comprising determining the characteristic from a model that relates that characteristic as a function of the amount of its components and properties of the components.
    Type: Application
    Filed: November 6, 2007
    Publication date: June 12, 2008
    Inventors: Jason Z. Gao, Peter Calcavecchio, Medi M. Hafez, Joan M. Kaminski, Liehpao Oscar Farng, David A. Blain, Gene Sanchez, Janet L. Lane
  • Patent number: 5496382
    Abstract: Reaction products of hydrocarbylsuccinic anhydrides, hydroxyl-containing amines and triazoles have been found to be effective antirust, antioxidant, anti-corrosion, antiwear, dispersant/detergent and thermal color stabilizing additives.
    Type: Grant
    Filed: September 14, 1994
    Date of Patent: March 5, 1996
    Assignee: Mobil Oil Corporation
    Inventors: David A. Blain, Andrew G. Horodysky, Ronald J. Poole, Shi-Ming Wu
  • Patent number: 5486301
    Abstract: Reaction products, in which aromatic acid bis(polyether ester) is added to succinimides, are effective antioxidants, dispersants, and detergents for fuels and lubricants.
    Type: Grant
    Filed: May 12, 1995
    Date of Patent: January 23, 1996
    Assignee: Mobil Oil Corporation
    Inventors: Guy P. Abramo, David A. Blain, Angeline B. Cardis
  • Patent number: 5456731
    Abstract: Reaction products of hydrocarbylcarboxylic anhydrides and aminoalkanols can provide effective antiwear, antirust, and corrosion-inhibiting properties in lubricant and fuel applications.
    Type: Grant
    Filed: June 29, 1994
    Date of Patent: October 10, 1995
    Assignee: Mobil Oil Corporation
    Inventors: David A. Blain, Robert H. Davis, Andrew G. Horodysky, Shi-Ming Wu