Abstract: A device for dynamic filtration of a pharmaceutical product is provided. The device includes a resin configured to selectively retain one or more components from a mixture having the pharmaceutical product, where the resin is configured to be activated by a medium of the mixture. The device further includes at least one positioning material disposed adjacent to the resin, where the positioning material is configured to provide mechanical support to the resin to at least partially retain the resin in position. In certain embodiments, the device does not require conditioning immediately prior to filtration.

Abstract: A search engine for databases, data streams, and other data sources allows user preferences as to the relative importance of search criteria to be used to rank the output of the search engine. A weighted preference generator generates weighted preference information including at least a plurality of weights corresponding to a plurality of search criteria. A weighted preference data search engine uses the weighted preference information to search a data source and to provide an ordered result list based upon the weighted preference information. A method for weighted preference data searching further includes allowing a user to re-rank the ordered result list and determine newly updated weighted preferences based on the re-ranking process. A plurality of weights signifying the relative importance of the search criteria may also be generated by the user inputting an ordered list. This ordered list may be a single alternative or a plurality of alternatives.

Abstract: A system described herein includes a selector component that receives input data that is desirably transformed by way of a Discrete Fourier Transform, wherein the selector component selects one of a plurality of algorithms for computing the Discrete Fourier Transform from a library based at least in part upon a size of the input function. An evaluator component executes the selected one of the plurality of algorithms to compute the Discrete Fourier Transform, wherein the evaluator component causes leverages shared memory of a processor to compute the Discrete Fourier Transform.

Abstract: Described is a technology for use with general discrete Fourier transforms (DFTs) performed on a graphics processing unit (GPU). The technology is implemented in a general library accessed through GPU-independent APIs. The library handles complex and real data of any size, including for non-power-of-two data sizes. In one implementation, the radix-2 Stockham formulation of the fast Fourier transform (FFT) is used to avoid computationally expensive bit reversals. For non-power of two data sizes, a Bluestein z-chirp algorithm may be used.

Abstract: Methods and apparatuses that facilitate dissolving a hyperpolarized agent within a polarizer and transporting it to a receiver is provided. The methods include delivering water to a hyperpolarized agent contained within a polarizer, forming a hyperpolarized aqueous solution, transporting the aqueous solution through a fluid path system out of the polarizer, filtering the aqueous solution through a partical size exclusion filter to a receiver, and modifying the pH of the filtered hyperpolarized aquous solution with a dissolution medium contained in the receiver. Also disclosed herein are apparatuses for dissolving a hyperpolarized agent comprising a vial for containing a hyperpolarized imaging agent therein, a dissolution fluid path, a delivery fluid path, a particle size exclusion filter, and a receiver connected to the particle size exclusion filter and positioned to receive the filtered aqueous solution of the hyperpolarized imaging agent.

Abstract: A system for gas-liquid separation in electrolysis processes is provided. The system includes a first compartment having a liquid carrier including a first gas therein and a second compartment having the liquid carrier including a second gas therein. The system also includes a gas-liquid separator fluidically coupled to the first and second compartments for separating the liquid carrier from the first and second gases.

Abstract: The present invention provides an apparatus and method for automated quality control of a substance comprising a compartment wherein a substance is located, a monitoring device coupled to the compartment and configured to monitor at least one quality control parameter prior to an end-use of the substance, and a processor coupled to the monitoring device, wherein the monitoring device is configured to communicate data to the processor for comparing at least one quality control parameter to an end-use value, and wherein the processor is further configured to control the release of the substance from the compartment to its end-use.

Abstract: A device for dynamic filtration of a pharmaceutical product is provided. The device includes a resin configured to selectively retain one or more components from a mixture having the pharmaceutical product, where the resin is configured to be activated by a medium of the mixture. The device further includes at least one positioning material disposed adjacent to the resin, where the positioning material is configured to provide mechanical support to the resin to at least partially retain the resin in position. In certain embodiments, the device does not require conditioning immediately prior to filtration.

Abstract: The present invention provides an apparatus and method for automated quality control of a substance comprising a compartment wherein a substance is located, a monitoring device coupled to the compartment and configured to monitor at least one quality control parameter prior to an end-use of the substance, and a processor coupled to the monitoring device, wherein the monitoring device is configured to communicate data to the processor for comparing at least one quality control parameter to an end-use value, and wherein the processor is further configured to control the release of the substance from the compartment to its end-use.

Abstract: A warning system for displaying a warning that a device unit is in use includes a sign unit configured to display warning information. A device unit includes a communication module configured to provide a wireless communication between the device unit and the sign unit such that when the device unit is activated, the communication module automatically transmits a wireless warning signal to the sign unit instructing the sign unit to display the warning information.

Abstract: A unitary, tamper-evident closure for use on the threaded neck of a container includes a molded plastic closure body having a series of internal threads, an annular, tamper-evident band constructed and arranged out of a suitable plastic for being ultrasonically welded to a portion of the container, a plurality of frangible elements constructed and arranged out of a suitable plastic for connecting the tamper-evident band to the closure body at a plurality of spaced-apart locations, and wherein the tamper-evident band is free of any undercut beads and the sole structural connection of the tamper-evident band to the container is by means of ultrasonic welding.

Abstract: A search engine for databases, data streams, and other data sources allows user preferences as to the relative importance of search criteria to be used to rank the output of the search engine. A weighted preference generator generates weighted preference information including at least a plurality of weights corresponding to a plurality of search criteria. A weighted preference data search engines uses the weighted preference information to search a data source and to provide an ordered result list based upon the weighted preference information. A method for weighted preference data searching includes determining weighted preference information including a plurality of search criteria and a corresponding plurality of weights signifying the relative importance of the search criteria, and querying a data source and ranking the results based upon the weighted preference information.

Abstract: A substrate coated with a deposited composite comprising uniformly dispersed hard martial particles in a glassceramic matrix. The deposited bulk composite may comprise uniformly dispersed hard material particles in a glassceramic matrix or hard material particles uniformly dispersed in a glassceramic matrix in a ratio of at least 20% by weight of glassceramic particles and at least 20% by weight of hard material; said mixture having a Vickers hardness of more than 2000 and up to 3000 kg/mm2 and demonstrates an extreme toughness, abrasive and wear resistance, high chemical inertness and a high cutting capability properties.

Abstract: A search engine for databases, data streams, and other data sources allows user preferences as to the relative importance of search criteria to be used to rank the output of the search engine. A weighted preference generator generates weighted preference information including at least a plurality of weights corresponding to a plurality of search criteria. A weighted preference data search engines uses the weighted preference information to search a data source and to provide an ordered result list based upon the weighted preference information. A method for weighted preference data searching includes determining weighted preference information including a plurality of search criteria and a corresponding plurality of weights signifying the relative importance of the search criteria, and querying a data source and ranking the results based upon the weighted preference information.

Abstract: A substrate coated with a deposited composite comprising uniformly dispersed hard am martial particles in a glassceramic matrix. The deposited bulk composite may comprise uniformly dispersed hard material particles in a glassceramic matrix or hard material particles uniformly dispersed in a glassceramic matrix in a ratio of at least 20% by weight of glassceramic particles and at least 20% by weight of hard material; said mixture having a Vickers hardness of more a 2000 and up to 3000 kg/mm2 and demonstrates an extreme toughness, abrasive and wear resistance, high chemical inertness and a high cutting capability properties.

Abstract: An improved method for depositing ferroelectric particles on a surface of a substrate to form films or stand-alone bodies. The improvement is based on electrophoretic deposition (EPD) of ferroelectric films by using a tri-functional phosphate ester additive having a concentration less than 10 volume percent in the EPD suspension, without the need for addition of a binder. The method includes preparation of the suspension by washing and dispersing ferroelectric particles, for example, commercially available PZT powder, in a polar solvent such as ethanol, followed by addition of the phosphate ester additive to the suspension, and an ultrasound treatment. The suspension is used in EPD of the ferroelectric particles on a prepared substrate. Following EPD, the green film is dried and sintered at high temperature.

Abstract: The present invention relates to a pharmaceutical composition comprising lisinopril and dibasic calcium phosphate dihydrate (DCPD), produced by a process comprising mixing lisinopril and DCPD with a specific surface area of less than 1.5 m2g−1. The use of large particle sized DCPD in a lisinopril formulation/composition has the effect of reducing the amount of the lisinopril degradation product DKP that is formed, thereby increasing the shelf-life of tablets formulated with the larger sized DCPD, particularly those with low doses of lisinopril.

Abstract: A method of depositing diamond particles on a surface of a substrate is provided. The method is effected by (a) charging the diamond particles by a positive charge to obtain positively charged diamond particles; and (b) electrophoretically depositing the positively charged diamond particles on the surface of the substrate, for obtaining a green diamond particles coat on the surface of the substrate.

Abstract: An improved method for depositing ferroelectric particles on a surface of a substrate to form films or stand-alone bodies. The improvement is based on electrophoretic deposition (EPD) of ferroelectric films by using a tri-functional phosphate ester additive having a concentration less than 10 volume percent in the EPD suspension, without the need for addition of a binder. The method includes preparation of the suspension by washing and dispersing ferroelectric particles, for example, commercially available PZT powder, in a polar solvent such as ethanol, followed by addition of the phosphate ester additive to the suspension, and an ultrasound treatment. The suspension is used in EPD of the ferroelectric particles on a prepared substrate. Following EPD, the green film is dried and sintered at high temperature.

Abstract: An improved method for depositing ferroelectric particles on a surface of a substrate to form films or stand-alone bodies. The improvement is based on electrophoretic deposition (EPD) of ferroelectric films by using a tri-functional phosphate ester additive having a concentration less than 10 volume percent in the EPD suspension, without the need for addition of a binder. The method includes preparation of the suspension by washing and dispersing ferroelectric particles, for example, commercially available PZT powder, in a polar solvent such as ethanol, followed by addition of the phosphate ester additive to the suspension, and an ultrasound treatment. The suspension is used in EPD of the ferroelectric particles on a prepared substrate. Following EPD, the green film is dried and sintered at high temperature.