Patents by Inventor David A. Canton

David A. Canton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Plasmid constructs for heterologous protein expression and methods of use
    Patent number: 11713467
    Abstract: Provided are plasmid vector constructs encoding multiple immunomodulatory proteins where each protein or component thereof can be expressed utilizing appropriate promotors and/or translation modifiers. Additional immunomodulatory proteins and genetic adjuvants containing shared tumor antigens can be added to further therapeutic potential as well as allow tracking of therapeutic treatment. Also provides are methods of expressing the plasmid constructs.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: August 1, 2023
    Assignee: OncoSec Medical Incorporated
    Inventors: Jean Campbell, David A. Canton, Robert H. Pierce
  • PLASMID CONSTRUCTS FOR TREATING CANCER AND METHODS OF USE
    Publication number: 20220041724
    Abstract: Described are expression cassettes encoding CD3-half-BiTE, CXCL9 and CTLA-4 scFv. The described expression cassettes can be used to treat cancer in a subject. Methods of delivering the expression cassettes to a tumor by direct intratumoral injection and electroporation are also described.
    Type: Application
    Filed: November 27, 2019
    Publication date: February 10, 2022
    Inventors: Christopher Twitty, Anandaroop Mukhopadhyay, David A. Canton, Mia Han, Erica Browning
  • MULTIGENE CONSTRUCT FOR IMMUNE-MODULATORY PROTEIN EXPRESSION AND METHODS OF USE
    Publication number: 20220040328
    Abstract: Provided are expression vector constructs encoding IL-12 p35 and IL-12 p40 proteins where each protein or component thereof can be expressed utilizing appropriate promoters and/or translation modifiers. Also provided are methods of use for the expression vectors.
    Type: Application
    Filed: December 11, 2019
    Publication date: February 10, 2022
    Inventor: David A. Canton
  • PLASMID CONSTRUCTS FOR HETEROLOGOUS PROTEIN EXPRESSION AND METHODS OF USE
    Publication number: 20210062218
    Abstract: Provided are plasmid vector constructs encoding multiple immunomodulatory proteins where each protein or component thereof can be expressed utilizing appropriate promoters and/or translation modifiers. Additional immunomodulatory proteins and genetic adjuvants containing shared tumor antigens can be added to further therapeutic potential as well as allow tracking of therapeutic treatment. Also provides are methods of expressing the plasmid constructs.
    Type: Application
    Filed: September 25, 2020
    Publication date: March 4, 2021
    Inventors: Jean Campbell, David A. Canton, Robert H. Pierce
  • MULTIGENE CONSTRUCT FOR IMMUNE-MODULATORY PROTEIN EXPRESSION AND METHODS OF USE
    Publication number: 20200123566
    Abstract: Provided are expression vector constructs encoding multiple immunomodulatory proteins where each protein or component thereof can be expressed utilizing appropriate promoters and/or translation modifiers. Additional immunomodulatory proteins and genetic adjuvants containing shared tumor antigens can be added to further therapeutic potential as well as allow tracking of therapeutic treatment. Also provided are methods of use for the expression vectors.
    Type: Application
    Filed: June 13, 2018
    Publication date: April 23, 2020
    Inventor: David A. Canton
  • Plasmid Constructs For Heterologous Protein Expression And Methods Of Use
    Publication number: 20190153469
    Abstract: Provided are plasmid vector constructs encoding multiple immunomodulatory proteins where each protein or component thereof can be expressed utilizing appropriate promotors and/or translation modifiers. Additional immunomodulatory proteins and genetic adjuvants containing shared tumor antigens can be added to further therapeutic potential as well as allow tracking of therapeutic treatment. Also provides are methods of expressing the plasmid constructs.
    Type: Application
    Filed: December 16, 2016
    Publication date: May 23, 2019
    Applicant: OncoSec Medical Incorporated
    Inventors: Jean Campbell, David A. Canton, Robert H. Pierce
  • Data display apparatus with character refresh buffer and row buffers
    Patent number: 4649379
    Abstract: A data display apparatus employs a raster scan cathode ray tube (1), a character refresh buffer (2) and three character row buffers (5,6,15) to address a character generator (3) in conjunction with a slice counter (4) or offset slice counter (18) under control of an events control module (20). This enables data within a partition on the CRT to be scrolled smoothly (scan-line-by-scan-line) and characters of different height (requiring different numbers of scans) to be displayed on the same row of the CRT.
    Type: Grant
    Filed: September 28, 1984
    Date of Patent: March 10, 1987
    Assignee: International Business Machines Corp.
    Inventors: David A. Canton, Brian L. Holloway, Nicholas B. Sargeant, Roger J. Llewelyn