Patents by Inventor David A. Coates

David A. Coates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TrkA Inhibitor
    Patent number: 11498915
    Abstract: The present invention relates to compound of the following structure for use as an inhibitor of TrkA, as well as compositions including this compound, and methods of using this compound for the treatment of pain including post-surgical pain, rheumatoid arthritis pain, neuropathic pain and osteoarthritis pain.
    Type: Grant
    Filed: May 24, 2021
    Date of Patent: November 15, 2022
    Assignee: ELI LILLY AND COMPANY
    Inventors: David A. Coates, Ryan James Linder, Laia Malet-Sanz
  • TrkA Inhibitor
    Publication number: 20210371399
    Abstract: The present invention relates to compound of the following structure for use as an inhibitor of TrkA, as well as compositions including this compound, and methods of using this compound for the treatment of pain including post-surgical pain, rheumatoid arthritis pain, neuropathic pain and osteoarthritis pain.
    Type: Application
    Filed: May 24, 2021
    Publication date: December 2, 2021
    Inventors: David A. Coates, Ryan James Linder, Laia Malet-Sanz
  • Aminopyridyloxypyrazole compounds
    Patent number: 9617243
    Abstract: The present invention relates to novel aminopyridyloxypyrazole compounds that inhibit the activity of transforming growth factor beta receptor 1 (TGF?R1), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, preferably colon cancer, melanoma, hepatocellular carcinoma, renal cancer, glioblastoma, pancreatic cancer, myelodysplastic syndrome, lung cancer, and gastric cancer, and/or fibrosis, preferably liver fibrosis and chronic kidney disease.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: April 11, 2017
    Assignee: Eli Lilly and Company
    Inventors: William T. McMillen, Sajan Joseph, Huaxing Pei, Jason Scott Sawyer, Gaiying Zhao, David A. Coates, Craig D. Wolfangel
  • Protein kinase inhibitors
    Patent number: 7855211
    Abstract: The present invention provides a compound of formula (I): or a pharmaceutically acceptable salt thereof which is useful in the treatment of cell proliferative diseases.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: December 21, 2010
    Assignee: Eli Lilly and Company
    Inventors: David A Coates, Lawrence Mark Gelbert, John M. Knobeloch, Alfonso De Dios Magana, Ana De Prado Gonzalez, Miriam Filadelfa Del Prado Catalina, Maria Cristina Garcia Paredes, Eva Maria Martin De La Nava, Maria Dolores Martin Ortega Finger, Jose Antonio Martinez Perez, Ana Isabel Mateo Herranz, Carlos Perez Martinez, Concepcion Sanchez Martinez
  • Disposable protective cap and process and apparatus for its production
    Patent number: 4459706
    Abstract: The invention relates to a disposable protective cap, particularly a disposable nurse's cap. The cap is formed from a rectangular sheet of nonwoven fabric having a pair of opposed side edges and a pair of opposed end edges. The sheet is pleated along longitudinal fold-lines parallel to the opposed pair of side edges and the pair of opposed side edges are secured together. The pleats are secured together at one end of the pleated sheet and the other end of the pleated sheet is at least partly elasticated to provide an expandable and contractable opening for the head. The invention also provides an apparatus and method for producing the cap and in particular an apparatus and method for the continuous production of the cap.
    Type: Grant
    Filed: July 29, 1981
    Date of Patent: July 17, 1984
    Assignee: Johnson & Johnson
    Inventors: Rory J. M. Smith, Brenda M. Sykes, Roger S. Terry, David A. Coates, Philip B. Gower