Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member configured to move between a collapsed configuration and an expanded configuration. The elongated tubular member may comprise at least one twisted filament, such as a knitted filament having a plurality of twisted knit stitches with intermediate rung portions extending between adjacent twisted knit stitches, or a plurality of helical filaments twisted with a plurality of longitudinal filaments.

Abstract: An ophthalmic device includes an optic including an optic axis and a closed-loop haptic structure coupled to the optic via a frame surrounding the optic, the closed-loop haptic structure including a closed loop extending from first and second attachment points to the frame. The closed loop includes a first hinge and a second hinge. The first hinge has a first section having a first component extending in a first angular direction, a second section having a second component extending in a second angular direction opposite to the first angular direction, and a first connecting section between the first section and the second section. The second hinge has a third section having a third component extending in the second angular direction, a fourth section having a fourth component extending in the first angular direction, the fourth section being connected to the second section to form the closed loop.

Abstract: A surgical device includes a handle assembly having a controller and an adapter assembly including a tubular housing having a proximal end portion configured to couple to the handle assembly and a distal end portion. The adapter assembly also includes a load sensing assembly disposed with the tubular housing. The load sensing assembly is configured to measure a load exerted on the tubular housing and includes: a sensor body having a pocket defined therein; a load sensor circuit disposed within the pocket and coupled to the sensor body; and a signal processing circuit disposed within the pocket and electrically coupled to the load sensor circuit. The load sensing assembly further includes a cover disposed over the pocket and enclosing the load sensor circuit and the signal processing circuit therein, the cover being coupled to the sensor body thereby forming a first hermetic seal therebetween.

Abstract: The present invention features interferon-free therapies for the treatment of HCV. Preferably, the treatment is over a shorter duration of treatment, such as no more than 12 weeks. In one aspect, the treatment comprises administering at least two direct acting antiviral agents to a subject with HCV infection, wherein the treatment lasts for 12 weeks and does not include administration of either interferon or ribavirin, and said at least two direct acting antiviral agents comprise (a) Compound 1 or a pharmaceutically acceptable salt thereof and (b) Compound 2 or a pharmaceutically acceptable salt thereof.

Abstract: Apparatus, systems, and methods are provided for generating a quantified indicator of cognitive skills in an individual. In certain configurations, the apparatus, systems, and methods can be implemented for enhancing cognitive skills in an individual.

Abstract: A battery interconnect may include a desired current capacity, integrated fusible links, and be manufacturable using cost effective techniques. In some embodiments, a battery interconnect includes a busbar and relatively thinner links. A busbar carries larger currents and accordingly its cross-sectional areas are relatively larger to reduce ohmic losses. A link carries a much smaller current, and a fusible link is configured to break the circuit when the current is above a threshold, thus requiring a relatively small cross-sectional area. These sometime disparate length scales are addressed using several techniques such as layering a busbar and a foil sheet and pressing portions of a busbar to form the links. The links can be affixed to a plurality of battery cells to connect the cells in parallel or series.

Abstract: Example implementations relate to a pressure regulator assembly for a closed fluid loop of a CDU. The pressure regulator assembly has a cylinder having an internal volume, and first and second hollow pistons slidably connected to the cylinder to split the internal volume into a first volume portion having cooling fluid, a second volume portion having driver fluid, and a third volume portion having compressible matter. The first volume portion is fluidically connected to the closed fluid loop. The first hollow piston is reciprocated by the compressible matter to maintain operating pressure of the cooling fluid in the closed fluid loop. The second hollow piston is driven by the driver fluid in response to predefined pressure drop of the cooling fluid during predefined time period, to inject additional cooling fluid from the first volume portion into the closed fluid loop to restore pressure level of cooling fluid to operating pressure.

Abstract: An illustrative stent may comprise an elongated tubular member having a first end and a second end and an intermediate region disposed therebetween. The elongated tubular member configured to move between a collapsed configuration and an expanded configuration. The elongated tubular member may comprise at least one twisted filament, such as a knitted filament having a plurality of twisted knit stitches with intermediate rung portions extending between adjacent twisted knit stitches, or a plurality of helical filaments twisted with a plurality of longitudinal filaments.

Abstract: An example medical device includes a stent having a radially expanding tubular framework. The radially expanding tubular framework includes a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending from the first end region to the second end region. The stent further includes a tubular structure positioned over the medial region, the tubular structure is formed from a bioabsorbable material, and is configured to hold the medial region in a first, compressed configuration. Upon bioabsorption of the tubular structure, the medial region of the tubular framework radially expands to a second, expanded configuration. One of the first end region or the second end region includes a first flange structure.

Abstract: An example medical device may include a stent including a radially expanding tubular framework having a radially outward surface, a radially inward surface, a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending from the first end region to the second end region. A first flange structure may be positioned near the first end region, and a second flange structure may be positioned near the second end region. One of the first end region or the second end region may include a third flange structure.

Abstract: The invention relates to a modular humeral prosthesis for an inverse shoulder prosthesis, comprising an anatomical shaft (1) and a separable epiphyseal head (2) which may be angularly orientated by rotation about the longitudinal axis (XX) of the anatomical shaft. The anatomical shaft and the epiphyseal head comprise complementary angular indexing means (11, 28) for relative rotational fixation.

Abstract: Systems and methods that provide improved cooling for batteries are disclosed. A battery system according to the present disclosure may include a cooling plate, one or more battery cells coupled to one surface of the cooling plate, and one or more battery cells coupled to the opposite surface of the cooling plate. The cooling plate and corresponding batteries may be included in a battery module, and multiple battery modules electrically connected may make up a battery pack. The cooling plates may comprise channels for cooling fluid, which may be provided to the plates in parallel from a cooling fluid source. Cooling the battery cells at the ends of the cells, where they are coupled to the cooling plate, may advantageously provide one or more of improved energy density, thermal management, and safety.

Abstract: Apparatus, systems, and methods are provided for generating a quantified indicator of cognitive skills in an individual. In certain configurations, the apparatus, systems, and methods can be implemented for enhancing cognitive skills in an individual.

Abstract: A fan assembly includes a fan body, a motor-driven impeller contained within the fan body and arranged to generate an air flow, a nozzle including a nozzle body having an air inlet arranged to receive the air flow from the fan body, and one or more air outlets arranged to emit the airflow from the fan assembly. The fan assembly further includes a nozzle retaining mechanism for releasably retaining the nozzle on the fan body, and a rotation mechanism for rotating the nozzle body relative to the fan body. The nozzle rotation mechanism includes a rotation motor arranged to drive a drive member and a driven member that is arranged to be driven by the drive member to rotate around a rotation axis.

Abstract: Embodiments of the present disclosure provide nanopore devices, such as nanopore sensors and/or other nanofluidic devices. In one or more embodiments, a nanopore device contains a substrate, an optional lower protective oxide layer disposed on the substrate, a membrane disposed on the lower protective oxide layer, and an optional upper protective oxide layer disposed on the membrane. The membrane has a pore and contains silicon nitride. The silicon nitride has a nitrogen to silicon ratio of about 0.98 to about 1.02 and the membrane has an intrinsic stress value of about ?1,000 MPa to about 1,000 MPa. The nanopore device also contains a channel extending through at least the substrate, the lower protective oxide layer, the membrane, the upper protective oxide layer, and the upper protective silicon nitride layer.

Abstract: Configuring device data streams (DDSs) of a mobile device is described herein. DDSs can include sensor data (captured from one or more sensors of the mobile device) and user-specific data (including application data from applications executed via the mobile device, as well as non-application data). DDS configuration parameters define modifications for the user-specific data and/or the sensor data of the DDS; these modifications can include removing or altering the user-specific data and/or the sensor data. DDSs can be sent to an external storage device via a network, and DDS modifications can be made at the mobile device or at the external storage device. Modified DDSs can be provided to requestors, and thus, the DDS configuration parameters allow a user to control what data is, or is not, included in a DDS for reasons related to privacy, data usage, etc.

Abstract: The present disclosure relates to systems, devices and procedures for forming flow paths within or across body lumens. In one example, a stent comprises an elongate body configured to expand between a first constrained configuration and a second unconstrained configuration. The elongate body in the second unconstrained configuration may include a first end, a second end, and a cylindrical saddle region extending therebetween. The first end may comprise a first retention member and a second retention member, and the second end may comprise a third retention member and a fourth retention member.

Abstract: Example implementations relate to a cool fluid reservoir for managing loss of cool fluid in a coolant distribution unit (CDU). The cool fluid reservoir includes a cylinder which has an internal volume defined between an inlet and outlet, and a hollow piston that is slidably connected to the cylinder via one of the inlet or outlet to split the internal volume into a first volume portion filled with the cool fluid and a second volume portion filled with driver fluid. The first volume portion is fluidically connected to a closed fluid loop of the CDU via the hollow piston and other one of the inlet or outlet. The hollow piston is slidably driven by the driver fluid to reduce the first volume portion and inject a portion of the cool fluid from the first volume portion into the closed fluid loop based on an operating pressure of the cool fluid.

Abstract: There is provided a fan assembly comprising a fan body, a motor-driven impeller contained within the fan body and arranged to generate an air flow, a nozzle comprising a nozzle body having an air inlet arranged to receive the air flow from the fan body and one or more air outlets arranged to emit the airflow from the fan assembly. The fan assembly further comprises a nozzle retaining mechanism for releasably retaining the nozzle on the fan body, and a rotation mechanism for rotating the nozzle body relative to the fan body. The nozzle rotation mechanism comprises a rotation motor arranged to drive a drive member and a driven member that is arranged to be driven by the drive member to rotate around a rotation axis, wherein the nozzle body comprises the driven member and the fan body comprises the rotation motor and the drive member.

Abstract: A battery interconnect may include a desired current capacity, integrated fusible links, and be manufacturable using cost effective techniques. In some embodiments, a battery interconnect includes a busbar and relatively thinner links. A busbar carries larger currents and accordingly its cross-sectional areas are relatively larger to reduce ohmic losses. A link carries a much smaller current, and a fusible link is configured to break the circuit when the current is above a threshold, thus requiring a relatively small cross-sectional area. These sometime disparate length scales are addressed using several techniques such as layering a busbar and a foil sheet and pressing portions of a busbar to form the links. The links can be affixed to a plurality of battery cells to connect the cells in parallel or series.