Abstract: Methods and systems for managing and/or processing a blockchain to maintain data security for confidential and/or personal data are provided. According to certain aspects, the disclosed data security techniques may enable access sharing functionality utilizing the blockchain. For example, access sharing may be utilized to file documents, share policy information, and/or comply with an audit. The data security techniques disclosed herein also enable the use of smart contracts to transfer funds associated with payment obligations and/or other forms of blockchain based payments, comply with anti-money laundering requirements, report industry data, validate interest payments and/or maintain agent sales data. Data security may be achieved through the use of public key/private key encryption techniques.

Abstract: This disclosure provides compounds of Formula (I), Formula (II), and pharmaceutically acceptable salts thereof, that inhibit phosphatidylinositol 4,5-bisphosphate 3-kinase (PI3K) isoform alpha (PI3Ka). These chemical entities are useful, e.g., for treating a condition, disease or disorder in which increased (e.g., excessive) PI3Ka activation contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also provides compositions containing the same as well as methods of using and making the same.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.

Abstract: This invention relates to novel whitening agents for cellulosic substrates. The whitening agents are comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. The whitening agents are further characterized by having a dispersion component value of the Hansen Solubility Parameter of less than or equal to about 17 MPa0.5. This invention also relates to laundry care compositions including but not limited to liquid and/or powder laundry detergent formulations and rinse added fabric softening (RAFS) compositions that comprise such whitening agents.

Abstract: A door structure system for a vehicle includes an inner panel, an outer panel, and an outer belt reinforcement member. The outer belt reinforcement member extends in a fore-and-aft direction of the door structure. The outer belt reinforcement member creates an overlap joint with a hem flange portion of the inner panel. The outer belt reinforcement member includes touch-down feature that extends toward the inner panel and into contact with a bearing surface of the inner panel that is stepped down relative to the hem flange portion. The overlap joint and the touch-down feature both contribute to an increased upper frame stiffness of the door structure and improve sealing performance between the door structure and the vehicle body structure.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.

Abstract: A modular water pipe case body, bottom and cap subassemblies that are assembled to contain a water pipe and optionally its accessories. The body subassembly includes a sheath that attaches to the bottom and cap subassemblies. The bottom subassembly includes an attachment portion that engages a base of the water pipe to keep it in place inside the water pipe case. The cap subassembly can include a storage compartment. An optional insert may be provided, which is inserted into the body and is configured to retain accessories for the water pipe.

Abstract: This invention relates to novel whitening agents for cellulosic substrates. The whitening agents are comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. The whitening agents are further characterized by having a dispersion component value of the Hansen Solubility Parameter of less than or equal to about 17 MPa0.5. This invention also relates to laundry care compositions including but not limited to liquid and/or powder laundry detergent formulations and rinse added fabric softening (RAFS) compositions that comprise such whitening agents.

Abstract: This invention relates to novel whitening agents for cellulosic substrates. The whitening agents are comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. The whitening agents are further characterized by having a dispersion component value of the Hansen Solubility Parameter of less than or equal to about 17 MPa0.5. This invention also relates to laundry care compositions including but not limited to liquid and/or powder laundry detergent formulations and rinse added fabric softening (RAFS) compositions that comprise such whitening agents.

Abstract: Methods of treating water to promote the health of aquatic organisms are described. The method may include introducing pulverized kaolin into the water. The pulverized kaolin may have a particle size distribution such that at least 30% by weight of the particles pass through a 60 mesh screen. For example, the pulverized kaolin may be in the form of a dry powder having a d50 diameter less than 300 ?m. The pulverized kaolin may remain dispersed or suspended in the water without dispersants and/or surfactants, e.g., to reduce the amount of at least one pathogenic microorganism present in the water and/or to reduce or prevent exposure of aquatic organisms to the pathogenic microorganism(s).

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, and G, are defined herein.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R7, G1 and G2, are defined herein.

Abstract: A medical device controller is provided that avoids unintended user inputs and unwanted medical device operation(s). A controller sends display commands to a graphical user interface (GUI) display to generate a first screen having a swipe field with no moving icons that prompts a user to initiate a designated operation by the medical device. When a valid swipe gesture is inputted, the controller generates a second screen with confirm button that requires a valid user press before the controller undertakes the designated operation, the controller generating and sending a command for the designated operation to the medical device when the controller determines that a valid user press has been inputted to the confirm button. The controller also sends commands to generate a status screen that transitions a rotating progress ring symbol and level indicator in accordance with a selected event to clearly indicate the status of medical device operations.

Abstract: Methods of treating water to promote the health of aquatic organisms are described. The method may include introducing pulverized kaolin into the water. The pulverized kaolin may have a particle size distribution such that at least 30% by weight of the particles pass through a 60 mesh screen. For example, the pulverized kaolin may be in the form of a dry powder having a d50 diameter less than 300 ?m. The pulverized kaolin may remain dispersed or suspended in the water without dispersants and/or surfactants, e.g., to reduce the amount of at least one pathogenic microorganism present in the water and/or to reduce or prevent exposure of aquatic organisms to the pathogenic microorganism(s).

Abstract: This invention relates to novel whitening agents for cellulosic substrates. The whitening agents are comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. The whitening agents are further characterized by having a dispersion component value of the Hansen Solubility Parameter of less than or equal to about 17 MPa0.5. This invention also relates to laundry care compositions including but not limited to liquid and/or powder laundry detergent formulations and rinse added fabric softening (RAFS) compositions that comprise such whitening agents.

Abstract: Compositions of clay materials intercalated with urea and/or another material or combination of materials are discussed. For example, the composition may comprise from about 20% to about 65% by weight intercalated urea, with respect to the total weight of the composition. Intercalation may be achieved, for example, by grinding the clay particles with one or more other materials, such that the other material(s) are intercalated into the clay particles. The composition may be formed into pills formulated for controlled release of urea, e.g., for fertilizing soil.

Abstract: This invention relates to novel whitening agents for cellulosic substrates. The whitening agents are comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. The whitening agents are further characterized by having a dispersion component value of the Hansen Solubility Parameter of less than or equal to about 17 MPa0.5. This invention also relates to laundry care compositions including but not limited to liquid and/or powder laundry detergent formulations and rinse added fabric softening (RAFS) compositions that comprise such whitening agents.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R7, G1 and G2, are defined herein.

Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT 1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, and G, are defined herein.