Patents by Inventor David A. DeBonville

David A. DeBonville has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Integral biomolecule preparation device
    Patent number: 5389339
    Abstract: An integral biomolecule preparation device which accomplishes all of the nucleic acid separation steps, including centrifugation, reagent addition, and pipeting, automatically without human intervention to fully automate the DNA separation procedure.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: February 14, 1995
    Assignee: Enprotech Corporation
    Inventors: Harry E. Petschek, Henry Kaufmann, Robert A. Quinlan, David A. DeBonville, Martin J. Sklar, Ronald D. Danehy, Michael Foley, John McG. Dobbs, David Banks
  • Method of recovering bacteriophage
    Patent number: 5204257
    Abstract: A method of recovering nucleic acid-containing particles from a liquid medium by contacting the liquid medium containing the particles with a mixture of hydroxylated silica beads and a salt solution to bind the nucleic acid-containing particles, centrifuging the mixture to pellet the bound particles, and separating the pellet from the liquid.
    Type: Grant
    Filed: April 29, 1991
    Date of Patent: April 20, 1993
    Assignee: Autogen Instruments, Inc.
    Inventors: David A. DeBonville, Kelley A. Logan
  • Nucleic acid separation method
    Patent number: 5096818
    Abstract: An improved method for isolating and purifying nucleic acid from cell culture media contemplating adding to resuspended cell solutions a lysing solution and neutralizing/deproteinating agent without mechanical mixing, followed by centrifugation to partially pellet cellular debris, mixing the solution to complete the reaction, and additional centrifugation to fully pellet the debris.
    Type: Grant
    Filed: June 4, 1990
    Date of Patent: March 17, 1992
    Assignee: AutoGen Instruments, Inc.
    Inventor: David A. DeBonville
  • Composition for isolating and purifying nucleic acid and improved method using same
    Patent number: 5047345
    Abstract: A composition for isolating and purifying nucleic acid from cell culture medium and a method for isolating and purifying nucleic acid from cell culture medium employing the composition, in which the reagent includes about 1 to 3.5M acetate salt solution, about 4 to 11.2M acetic acid, about 1 to 40% by volume phenol, and about 1 to 40% by volume chloroform.
    Type: Grant
    Filed: June 2, 1989
    Date of Patent: September 10, 1991
    Assignee: Genetics Institute
    Inventors: David A. DeBonville, Gerard E. Riedel
  • Novel composition for nucleic acid purification
    Patent number: 4843012
    Abstract: A storage stable single phase aqueous composition is provided which is useful in isolatin nucleic acids from cell or virus cultures.
    Type: Grant
    Filed: September 17, 1986
    Date of Patent: June 27, 1989
    Assignee: Genetics Institute, Inc.
    Inventors: David A. DeBonville, Gerard E. Riedel
  • Method for the isolation and purification of DNA molecules
    Patent number: 4833239
    Abstract: A method for isolating and purifying nucleic acids from eukaryotic and prokaryotic cell cultures or viral cell cultures.
    Type: Grant
    Filed: January 29, 1987
    Date of Patent: May 23, 1989
    Assignee: Genetics Institute, Inc.
    Inventors: David A. DeBonville, Gerard E. Riedel