Patents by Inventor David A. Egan

David A. Egan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240081183
    Abstract: A leaf harvester includes a mobile vehicle, configured for moving on ground, having a leaf cutter at a front thereof, a first conveyor, and a laminar flow air conveyor, disposed between the leaf cutter and the first conveyor. The laminar flow air conveyor has a sloped upper surface, and is configured to rearwardly discharge a laminar flow of air over the upper surface to propel leaves cut by the leaf cutter to the first conveyor.
    Type: Application
    Filed: September 12, 2022
    Publication date: March 14, 2024
    Inventors: David Offerdahl, Jordan Egan
  • Publication number: 20220289858
    Abstract: The present invention encompasses antagonist anti-CD40 antibodies and antigen-binding portions thereof. Specifically, the invention relates to humanized anti-CD40 antibodies. In certain embodiments, antibodies of the invention neutralize human CD40 (hCD40) activity. Antibodies, or antibody portions, of the invention are useful for detecting CD40 and for inhibiting CD40 activity, e.g., in a human subject suffering from a disorder in which CD40 activity is detrimental.
    Type: Application
    Filed: October 7, 2021
    Publication date: September 15, 2022
    Inventors: Lorenzo Benatuil, Maria A. Argiriadi, Bradford L. Mcrae, Chung-Ming Hsieh, David A. Egan, John E. Harlan, Russell A. Judge, Rui Wang, Gillian A. Kingsbury
  • Publication number: 20210312797
    Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).
    Type: Application
    Filed: March 24, 2020
    Publication date: October 7, 2021
    Inventors: Mark Anderson, Jieyi Wang, Archana Thakur, Debra Chao, Chung-Ming Hsieh, Qian Zhang, Edward B. Reilly, Enrico L. Digiammarino, Kenton L. Longenecker, Russell A. Judge, David A. Egan, Charles W. Hutchins
  • Publication number: 20210074147
    Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).
    Type: Application
    Filed: March 24, 2020
    Publication date: March 11, 2021
    Inventors: Mark Anderson, Jieyi Wang, Archana Thakur, Debra Chao, Chung-Ming Hsieh, Qian Zhang, Edward B. Reilly, Enrico L. Digiammarino, Kenton L. Longenecker, Russell A. Judge, David A. Egan, Charles W. Hutchins
  • Publication number: 20190359725
    Abstract: The present invention encompasses antagonist anti-CD40 antibodies and antigen-binding portions thereof. Specifically, the invention relates to humanized anti-CD40 antibodies. In certain embodiments, antibodies of the invention neutralize human CD40 (hCD40) activity. Antibodies, or antibody portions, of the invention are useful for detecting CD40 and for inhibiting CD40 activity, e.g., in a human subject suffering from a disorder in which CD40 activity is detrimental.
    Type: Application
    Filed: December 21, 2018
    Publication date: November 28, 2019
    Inventors: Lorenzo Benatuil, Maria A. Argiriadi, Bradford L. McRae, Chung-Ming Hsieh, David A. Egan, John E. Harlan, Russell A. Judge, Rui Wang, Gillian A. Kingsbury
  • Patent number: 10476882
    Abstract: An online system provides a social networking environment for a set of users, such as members of an organization. The online system allows generation of groups of users within the set to allow users to more easily communicate content with other users. When a user creates a new group, the online system identifies multiple categories to the user, and the user selects a category for association with the group. Categories are associated with access rights regulating user access to content associated with the group or users capable of performing various actions with the group. Additionally, a member of the group may invite entities outside of the online system, or outside of the set of users, to join the group. If the entity joins the group, the online system provides content associated with the group to the entity, allowing the entity to receive content from the group.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: November 12, 2019
    Assignee: Facebook, Inc.
    Inventors: John David Egan, Tarmo Lehtpuu, Blaise Andrew DiPersia
  • Publication number: 20190153110
    Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).
    Type: Application
    Filed: November 27, 2018
    Publication date: May 23, 2019
    Inventors: Mark Anderson, Jieyi Wang, Archana Thakur, Debra Chao, Chung-Ming Hsieh, Qian Zhang, Edward B. Reilly, Enrico L. Digiammarino, Kenton L. Longenecker, Russell A. Judge, David A. Egan, Charles W. Hutchins
  • Patent number: 10184003
    Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: January 22, 2019
    Assignee: AbbVie Inc.
    Inventors: Mark Anderson, Jieyi Wang, Archana Thakur, Debra Chao, Chung-Ming Hsieh, Qian Zhang, Edward B. Reilly, Enrico L. Digiammarino, Kenton L. Longenecker, Russell A. Judge, David A. Egan, Charles W. Hutchins
  • Patent number: 10075825
    Abstract: An online system allows users to join groups and interact with other members of group that they have joined. The online system identifies relationships between users in an organization using information about the users, such as roles and connections from an organizational chart. The online system establishes inferred connections between the users based on information from the organizational chart. The online system then determines whether to make group content visible to a user by applying visibility criteria for a group to the inferred connections between a user and members of the group, if any. Depending on this determination, groups are then made visible to certain users by presenting content associated with the group to the user.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: September 11, 2018
    Assignee: Facebook, Inc.
    Inventors: John David Egan, Lars Eilstrup Rasmussen, Fabio Lopiano
  • Publication number: 20180128846
    Abstract: Disclosed herein is a system and computer implemented method for detecting extraordinary demand of a consumable(s) for processing biological samples by laboratory instrument(s) in a plurality of laboratories based on exceptional deviations from usual demand levels of trigger laboratories in the proximity of a target laboratory.
    Type: Application
    Filed: October 27, 2017
    Publication date: May 10, 2018
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Thomas Baeriswyl, David Egan
  • Publication number: 20180083976
    Abstract: An online system provides a social networking environment for a set of users, such as members of an organization. The online system allows generation of groups of users within the set to allow users to more easily communicate content with other users. When a user creates a new group, the online system identifies multiple categories to the user, and the user selects a category for association with the group. Categories are associated with access rights regulating user access to content associated with the group or users capable of performing various actions with the group. Additionally, a member of the group may invite entities outside of the online system, or outside of the set of users, to join the group. If the entity joins the group, the online system provides content associated with the group to the entity, allowing the entity to receive content from the group.
    Type: Application
    Filed: September 22, 2016
    Publication date: March 22, 2018
    Inventors: John David Egan, Tarmo Lehtpuu, Blaise Andrew DiPersia
  • Publication number: 20170237810
    Abstract: An online system allows users to join groups and interact with other members of group that they have joined. The online system identifies relationships between users in an organization using information about the users, such as roles and connections from an organizational chart. The online system establishes inferred connections between the users based on information from the organizational chart. The online system then determines whether to make group content visible to a user by applying visibility criteria for a group to the inferred connections between a user and members of the group, if any. Depending on this determination, groups are then made visible to certain users by presenting content associated with the group to the user.
    Type: Application
    Filed: February 17, 2016
    Publication date: August 17, 2017
    Inventors: John David Egan, Lars Eilstrup Rasmussen, Fabio Lopiano
  • Publication number: 20170022281
    Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).
    Type: Application
    Filed: June 7, 2016
    Publication date: January 26, 2017
    Applicant: AbbVie Inc.
    Inventors: Mark Anderson, Jieyi Wang, Archana Thakur, Debra Chao, Chung-Ming Hsieh, Qian Zhang, Edward B. Reilly, Enrico L. Digiammarino, Kenton L. Longenecker, Russell A. Judge, David A. Egan, Charles W. Hutchins
  • Publication number: 20150058057
    Abstract: Systems, computer implemented methods, and computer readable media select potential meeting times and meeting locations. Meeting parameters are generated for a meeting request. Scores for each of a plurality of meeting times are generated based on the meeting parameters. Scores for each of a plurality of meeting locations are generated based on the meeting parameters. One or more potential meeting time and meeting location pairs are selected based on the scores for each of the plurality of meeting times and the scores for each of the plurality of meeting locations.
    Type: Application
    Filed: August 22, 2013
    Publication date: February 26, 2015
    Inventors: John David EGAN, Scott MacVICAR, Eric SUMNER
  • Publication number: 20140227294
    Abstract: The present invention encompasses PRLR binding proteins. Specifically, the invention relates to antibodies that are chimeric, CDR grafted and humanized antibodies. Preferred antibodies have high affinity for hPRLR and neutralize hPRLR activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hPRLR and for inhibiting hPRLR activity, e.g., in a human subject suffering from a disorder in which hPRLR activity is detrimental. Also included in the invention are anti-PRLR antibody drug conjugates (ADCs).
    Type: Application
    Filed: December 23, 2013
    Publication date: August 14, 2014
    Applicant: ABBVIE INC.
    Inventors: Mark Anderson, Jieyi Wang, Archana Thakur, Debra Chao, Chung-Ming Hsieh, Qian Zhang, Edward B. Reilly, Enrico L. DiGiammarino, Kenton L. Longenecker, Russell A. Judge, David A. Egan, Charles W. Hutchins
  • Patent number: 7976596
    Abstract: A method of producing a high-density abrasive compact material includes the steps of providing an electrically conductive mixture of a bonding powder material and abrasive particles or grit; compressing the electrically conductive mixture; and subjecting the compressed electrically conductive mixture to one or more high current pulses to form the abrasive compact is provided.
    Type: Grant
    Filed: September 9, 2005
    Date of Patent: July 12, 2011
    Assignee: Element Six Limited
    Inventors: David Egan, Gerald F. Flynn
  • Publication number: 20100062253
    Abstract: The invention relates to a process for the formation of pellets containing an ultra hard core coated with an encapsulating material, the process including the steps of suspending ultra hard core material in a flow of gas; contacting the ultra hard core material with encapsulating to form pellets, introducing the pellets into a rotating vessel and contacting the pellets with encapsulating material to form pellets of greater mass than the pellets introduced into the rotating vessel. The invention also relates to a pellet containing an ultra hard core coated with an encapsulating material whenever produced by a process as hereinbefore described.
    Type: Application
    Filed: August 13, 2007
    Publication date: March 11, 2010
    Inventors: David Egan, Derek Norman Wright, Gerald F. Flynn
  • Publication number: 20080168718
    Abstract: A method of producing a high-density abrasive compact material includes the steps of providing an electrically conductive mixture of a bonding powder material and abrasive particles or grit; compressing the electrically conductive mixture; and subjecting the compressed electrically conductive mixture to one or more high current pulses to form the abrasive compact is provided.
    Type: Application
    Filed: September 9, 2005
    Publication date: July 17, 2008
    Inventors: David Egan, Gerald F. Flynn
  • Publication number: 20070214727
    Abstract: A coated super-hard abrasive comprises a core of super-hard abrasive material, typically diamond or cBN based, an inner layer of a metal carbide, nitride, boride, carbonitride or boronitride chemically bonded to an outer surface of the super-hard abrasive material and an outer layer of a metal, metal alloy or a combination of metals or metal alloys deposited on the inner layer. Examples of metals or metal alloys that can be applied as an outer layer include metals from group IVa, Va or Vla transition metals, including tungsten, titanium, chromium, molybdenum, and zirconium, and metals from the first row transition metals (Ti to Cu), particularly the non magnetic metals or alloys of these that are amenable to magnetron sputtering, and elements from groups IIIb and IVb of the periodic table, such as B, Al, Si.
    Type: Application
    Filed: January 13, 2005
    Publication date: September 20, 2007
    Inventors: David Egan, Johannes Engels, Michael Fish
  • Publication number: 20070157525
    Abstract: A method of producing coated ultra-hard abrasive material, in particular coated diamond and CBN material. In a first step, an element capable of forming (singly or in combination) carbides, nitrides or borides to the surface(s) of the abrasive material is is applied using a hot coating process. At least one outer layer of a coating material selected from the group comprising transition metals, carbide, nitride, boride, oxide and carbonitride forming metals, metal carbides, metal nitrides, metal borides, metal oxides and metal carbonitrides, boronitrides and borocarbonitrides is applied over the inner layer by physical vapour deposition or chemical vapour deposition. Typically the inner layer elements come from groups IVa, Va, VIa, IIIb and IVb of the periodic table and include, for example, vanadium, molybdenum, tantalum, indium, zirconium, niobium, tungsten, aluminium, boron and silicon.
    Type: Application
    Filed: January 13, 2005
    Publication date: July 12, 2007
    Inventors: David Egan, Johannes Engels, Michael Fish