Patents by Inventor David A. Eiznhamer

David A. Eiznhamer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRAZOLE DERIVATIVES AS MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY
    Publication number: 20190382348
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Application
    Filed: January 11, 2019
    Publication date: December 19, 2019
    Inventors: David E. Zembower, David A. Eiznhamer
  • Pyrazole derivatives as modulators of hepatocyte growth factor (scatter factor) activity
    Patent number: 9663471
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Grant
    Filed: October 7, 2013
    Date of Patent: May 30, 2017
    Assignee: Angion Biomedica Corporation
    Inventors: David E. Zembower, David A. Eiznhamer
  • PYRAZOLE DERIVATIVES AS MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY
    Publication number: 20140256780
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Application
    Filed: October 7, 2013
    Publication date: September 11, 2014
    Applicant: Angion Biomedica Corporation
    Inventors: David E. Zembower, David A. Eiznhamer
  • Small molecule modulators of hepatocyte growth factor (scatter factor) activity
    Patent number: 8580834
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: November 12, 2013
    Assignee: Angion Biomedica Corp.
    Inventors: David E. Zembower, David A. Eiznhamer
  • 23-Substituted Derivatives of Lupane-type Pentacyclic Triterpenoids
    Publication number: 20100144688
    Abstract: The present invention comprises small molecule inhibitors of cell proliferative conditions, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprises pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
    Type: Application
    Filed: December 9, 2009
    Publication date: June 10, 2010
    Applicant: ADVANCED LIFE SCIENCES, INC.
    Inventors: Ali Koohang, Aye Aye Mar, Erika Szotek, Ze-Qi Xu, David A. Eiznhamer, Michael T. Flavin
  • Lupane-Type Triterpenoids Modified at 30-Position and Analogues Thereof
    Publication number: 20090062243
    Abstract: The present invention comprises lupine-type triterpenoids that inhibit cell proliferations, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
    Type: Application
    Filed: July 10, 2008
    Publication date: March 5, 2009
    Applicant: ADVANCED LIFE SCIENCES, INC.
    Inventors: Ali Koohang, Aye Aye Mar, Erika Szotek, Ze-Qi Xu, David A. Eiznhamer, Michael T. Flavin
  • Small molecule modulators of hepatocyte growth factor (scatter factor) activity
    Patent number: 7265112
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: September 4, 2007
    Assignee: Angion Biomedica Corp.
    Inventors: David E. Zembower, David A. Eiznhamer
  • Small molecule modulators of hepatocyte growth factor (scatter factor) activity
    Patent number: 7250437
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: July 31, 2007
    Assignee: Angion Biomedica Corp.
    Inventors: David E. Zembower, David A. Eiznhamer
  • Small molecule modulators of hepatocyte growth factor (scatter factor) activity
    Patent number: 7192976
    Abstract: The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role.
    Type: Grant
    Filed: December 18, 2003
    Date of Patent: March 20, 2007
    Assignee: Angion Biomedica Corporation
    Inventors: David E. Zembower, David A. Eiznhamer
  • Small molecule modulators of hepatocyte growth factor (scatter factor) activity
    Publication number: 20040180882
    Abstract: The present invention provides compounds having formula (I): 1
    Type: Application
    Filed: December 18, 2003
    Publication date: September 16, 2004
    Inventors: David E. Zembower, David A. Eiznhamer