Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).

Abstract: A system for reconstructing an image of an object includes a mobile imaging system, and a user removable module configured to be attached to the mobile imaging system.

Abstract: A generally cylindrical quick disconnect female cryogenic coupler, interconnected with a cryogenic fluid transfer apparatus, includes a coupler body with a first cavity housing a laterally severed tubular bushing, an adaptor having one end attached to the coupler body and another end to the apparatus, a normally closed-biased valve between the coupler body and the adaptor, a coupling sleeve, attached to the coupler body having, a frusto-conical inlet portion, and a vent fitting having one end connected with a coupling sleeve radial aperture and another end in operative connection with a cryogenic fluid storage vessel, associated with the noted apparatus, to permit the inlet purging by using the vessel's own gaseous phase as a purging medium during liquid fluid transfer operation. The severed bushing inhibits ice formation, at an inlet/male nipple interface during the noted transfer. A method for purging moisture at the noted interface is also set forth.

Abstract: A system and method for automatically completing a formula of a spreadsheet application, calculator application, accounting application, business application or banking application. One aspect of the present invention is a computer-implemented method for automatically completing formulaic cell data. The computer-implemented method includes a step for substantiating an autocomplete process in response to a user input of formulaic cell data and aggregating autocomplete options based on the user input. Another aspect of the present invention includes displaying a dynamic list of autocomplete options when the user input is a trigger.

Abstract: There is disclosed an integrated project management and risk management system. A risk processor has access to a project data store containing a plurality of inter-related project actions used for project management purposes, and a risk data store which contains a plurality of inter-related project activities and associated risk indicators used for related risk management purposes. The risk processor is operable to generate and write to the risk data store changes to the project activities and risk indicators reflecting changes in the project actions, to generate or receive mitigating activities identified to reduce or prevent a risk or the consequences of a risk associated with a project activity and to write corresponding project action changes to the project data store.

Abstract: The present invention relates to a class of substituted triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).

Abstract: The present invention relates to a system and methodology providing automation services in a distributed industrial controller environment. In one aspect of the present invention, a data access service is provided that includes, sending and receiving data to and from a data access service namespace operative in the distributed controller environment. In another aspect of the present invention, an alarming service is provided wherein data values are monitored in a server component according to predetermined conditions configured by a user or other entity. If the data values are determined to be outside of boundaries as defined by the predetermined conditions, an alarm can be communicated to a plurality of other components cooperating in the distributed environment.

Abstract: The present invention relates to a class of substituted 1,2,4-triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.).

Abstract: The invention is directed to pyridazinone compounds and pharmaceutical compositions containing such compounds that are useful in treating infections by hepatitis C virus.

Abstract: Certain embodiments of the present invention provide a system for coordinating a radiological imaging subsystem with a component including: a first communication device located on the radiological imaging subsystem; and a second communication device located on the component, wherein the first and second communication devices are capable of communicating to indicate a positional relationship between the radiological imaging subsystem and the component. In an embodiment, the component includes an imaging table. In an embodiment, at least one range of motion of the radiological imaging system is determinable based at least in part on the communicating to indicate a positional relationship. In an embodiment, the at least one range of motion of the radiological imaging system includes at least one range of motion of a gantry.

Abstract: The present invention is directed towards a method for making a healthy snack food having an appearance and taste similar to conventional fried snack products without the use of an oil-frying process. The method of the present invention includes the steps of providing food slices from a starch-based food or dough. The food slices can be blanched and a controlled amount of oil can be added to enhance final organoleptical properties. The food slices are then rapidly dehydrated to a much lower moisture content in a primary drying step that simulates conventional frying dehydration rates. A food snack, such as a corn or potato-based snack, produced by this method is a low-fat, ready-to-eat snack having the conventional texture and taste associated with fried snack products.

Abstract: The present invention relates to a system and methodology providing a virtual “namespace” architecture between client and server components in an industrial automation environment, wherein the namespace can be a structured store of logical names, instances and definitions, together with access and modification components. An Active Directory Service Interface (ADSI) family can be employed, for example, to navigate and access the namespace structure and contents. The present invention employs the concept of a “service” to encapsulate server-side behavior accessed through the namespace. Thus, logical names can be utilized to decouple client components from the physical location and implementation of server components. Some services, known as “basic services”, may ignore the logical container structure exposed by an area model in a namespace. By contrast, services which utilize an area context and a set of named service items to interact with clients can be referred to as “namespace extensions.

Abstract: This invention relates to a carotenoid composition comprising the carotenoid as particles of size smaller than 100 nanometers in an oil medium and a method of preparing the composition by milling the carotenoid in an oil medium and therapeutic compositions containing the carotenoid.

Abstract: The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ?-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.

Abstract: The present invention is direct to a method of producing analgesia in a mammalian subject. The method includes administering to the subject an omega conopeptide, preferably ziconotide, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyil, buprenorphine, and sufentanil, or its pharmaceutically acceptable salts thereof, wherein the ?-conopeptide retains its potency and is physically and chemically compatible with the analgesic compound. A preferred route of administration is intrathecal administration, particularly continuous intrathecal infusion. The present invention is also directed to a pharmaceutical formulation comprising an omega conopeptide, preferably ziconotide, an antioxidant, in combination with an analgesic selected from the group consisting of morphine, bupivicaine, clonidine, hydromorphone, baclofen, fentanyl, buprenorphine, and sufentanil.

Abstract: The present invention relates to a class of substituted 1,2,4-triazoles of formula (I) with activity as oxytocin antagonists, uses thereof, processes for the preparation thereof and compositions containing said inhibitors. These inhibitors have utility in a variety of therapeutic areas including sexual dysfunction, particularly premature ejaculation (P.E.

Abstract: An X-ray tube housing with integrated cooling passages in the walls of the X-ray tube housing, through which a liquid or gas coolant is circulated and the heat is transferred from the X-ray tube housing to an external cooler. The integrated cooling passages are created around the perimeter of the X-ray tube housing as the X-ray tube housing is formed. For a rotating anode X-ray tube using an oil coolant, the path of heat transfer is from the anode to the glass insert and oil by the means of radiation. The oil that is in contact with the glass insert conducts heat away form the insert to the X-ray tube housing which is then cooled by the integrated cooling passages located within the X-ray tube housing through which fluid is passed to an external fluid cooling system.

Abstract: An inspection system for removably mounting to a platform movable in relation to a generally upright mast for inspection of the mast has a mounting support assembly removably fixable to the platform. The mounting support assembly for scanning the mast carries a detector device and collecting mast scanned information. A power supply is carried by one or more of the mounting support assembly or the detector device and is connected to the detector device. A communications device is carried by one or more of the mounting support assembly or the detector device and is connected to the detector device for receiving and relaying the collected mast scanned information.

Abstract: This invention relates to compounds of formula (I)