Abstract: Methods, systems, and devices for patient monitoring are described. The method may include receiving data related to a physiological parameter of a patient. The method may further include displaying information related to the physiological parameter of the patient in order to indicate how the patient is trending. In some cases, the method may include adjusting the received data and determining a subset of the adjusted values to display at a computing device. In some other cases, the method may include displaying a health indicator based on the health record of the patient on the computing device. The position of the health indicator may be based on a medical relationship between the data indicated by the health indicator and the physiological parameter.

Abstract: A method of treating a T-cell mediated disease in a subject by administering to the subject a therapeutically effective amount of an antibody or fragment thereof that specifically binds to CD6 is described. Humanized antibodies useful for the method are also described.

Abstract: A method of treating a T-cell mediated disease in a subject by administering to the subject a therapeutically effective amount of an antibody or fragment thereof that specifically binds to CD6 is described. Humanized antibodies useful for the method are also described.

Abstract: Provided herein are compositions and methods for cancer immunotherapy. In particular, provided herein are compositions and methods for blocking CD6 binding to ligands on cancer cells.

Abstract: Provided herein are compositions, systems, kits, and methods for detecting autoimmune disease (e.g., multiple sclerosis and juvenile idiopathic arthritis), and risk of autoimmune disease, in a subject based on the levels of CD318.

Abstract: The disclosure provides materials and methods useful in modulating the course of autoimmune disorders that are monocyte-dependent and/or angiogenesis-dependent by administering inhibitors of aminopeptidase N/CD13.

Abstract: Methods, systems, and devices for patient monitoring are described. The method may include receiving data related to a physiological parameter of a patient. The method may further include displaying information related to the physiological parameter of the patient in order to indicate how the patient is trending. In some cases, the method may include adjusting the received data and determining a subset of the adjusted values to display at a computing device. In some other cases, the method may include displaying a health indicator based on the health record of the patient on the computing device. The position of the health indicator may be based on a medical relationship between the data indicated by the health indicator and the physiological parameter.

Abstract: A method of treating a T-cell mediated disease in a subject by administering to the subject a therapeutically effective amount of an antibody or fragment thereof that specifically binds to CD6 is described. Humanized antibodies useful for the method are also described.

Abstract: A method of treating a T-cell mediated disease in a subject by administering to the subject a therapeutically effective amount of an antibody or fragment thereof that specifically binds to CD6 is described. Humanized antibodies useful for the method are also described.

Abstract: A GSM, UMTS or LTE mobile telecommunications network includes a radio access network comprising base stations, and further includes one or more additional access points. An access point may be connected to the network core by an IP transport broadband connection. The access point is configured to appear to the mobile terminal as a base station. Arrangements are disclosed which allow the network to restrict access to the network via these access points whilst also minimizing signaling requirements. The access points may be excluded from traditional Tracking Areas, but associated therewith by a network controller in a mapping in order to notify authorized mobile terminals of the Access Point's existence.

Abstract: Provided herein are compositions, systems, kits, and methods for detecting autoimmune disease (e.g., multiple sclerosis and juvenile idiopathic arthritis), and risk of autoimmune disease, in a subject based on the levels of CD318.

Abstract: A GSM, UMTS or LTE mobile telecommunications network includes a radio access network comprising base stations, and further includes one or more additional access points. An access point may be connected to the network core by an IP transport broadband connection. The access point is configured to appear to the mobile terminal as a base station. Arrangements are disclosed which allow the network to restrict access to the network via these access points whilst also minimizing signaling requirements. The access points may be excluded from traditional Tracking Areas, but associated therewith by a network controller in a mapping in order to notify authorized mobile terminals of the Access Point's existence.

Abstract: A brushless, three phase wound field synchronous machine (WFSM) provides an electromechanical power transfer system wherein it may serve as both a starter and a generator. Power for the excitation system of the WFSM is provided by a three phase flux switching generator (FSG). The three phase FSG also provides position sensor functionality for the WFSM when the WFSM operates in the starter/motor mode.

Abstract: A DC/DC converter includes an internal transistor and a current sensor that is operable to sense a current passing through the transistor. The DC/DC converter also includes an output current estimator module that estimates the output current based on the sensed transistor current.

Abstract: An oral care kit is provided. The oral care kit is designed to be used to treat a painful area of a patient's mouth, such as a tooth, an area of a lip, or an area along a gum line. The oral care kit generally includes a topical anesthetic, a plurality of disposable swabs, and an applicator. The applicator has a proximal end defining a handle, and a distal end comprising a pair of prongs. A channel is formed along an inner surface of the prongs. The proximal end of each swab is dimensioned to be slidably received within the channel, while the distal end comprises flocking. Each of the disposable swabs is dimensioned to be received within a user's mouth for application of the topical anesthetic. A method of numbing a dental area is also provided herein.

Abstract: A system for sensing voltage in an isolated converter includes an input circuit isolated from an output circuit using a first transformer, the first transformer having a primary coil and a secondary coil, wherein the output circuit includes an output inductor and an output capacitor, and wherein the input circuit includes a power source that provides power to the output circuit through the first transformer; a feedback winding coupled to the output inductor to form a second transformer; and a monitor circuit that calculates a voltage across the output capacitor using a voltage across the feedback winding, a voltage across the primary coil of the first transformer, a turns ratio of the first transformer, and a turns ratio of the second transformer in order to provide feedback to control the input circuit.

Abstract: A brushless, three phase wound field synchronous machine (WFSM) provides an electromechanical power transfer system wherein it may serve as both a starter and a generator. Power for the excitation system of the WFSM is provided by a three phase flux switching generator (FSG). The three phase FSG also provides position sensor functionality for the WFSM when the WFSM operates in the starter/motor mode.

Abstract: A system for sensing voltage in an isolated converter includes an input circuit isolated from an output circuit using a first transformer, the first transformer having a primary coil and a secondary coil, wherein the output circuit includes an output inductor and an output capacitor, and wherein the input circuit includes a power source that provides power to the output circuit through the first transformer; a feedback winding coupled to the output inductor to form a second transformer; and a monitor circuit that calculates a voltage across the output capacitor using a voltage across the feedback winding, a voltage across the primary coil of the first transformer, a turns ratio of the first transformer, and a turns ratio of the second transformer in order to provide feedback to control the input circuit.

Abstract: A DC/DC converter includes an internal transistor and a current sensor that is operable to sense a current passing through the transistor. The DC/DC converter also includes an output current estimator module that estimates the output current based on the sensed transistor current.

Abstract: A remote power controller (RPC) includes a line connection; a load connection; a first field effect transistor (FET) and a second FET arranged in parallel between the line connection and the load connection, wherein the first FET has a lower safe operating area (SOA) than a SOA of the second FET, and wherein the first FET has a lower resistance at saturation (RDS(on)) than the second FET; and a voltage offset element connected between the first FET and the second FET, such that in the event that a current in the RPC is above a current limiting setpoint, the voltage offset element is configured to cause the first FET to turn off.