Abstract: A system and method are described for determining candidate fiducial marker locations in the vicinity of a lesion. Imaging information and data are input or received by the system and candidate marker locations are calculated and displayed to the physician. Additionally, interactive feedback may be provided to the physician for manually selected or identified sites. The physician may thus receive automatic real time feedback for a candidate fiducial marker location and adjust or accept a constellation of fiducial marker locations. 3D renderings of the airway tree, lesion, and marker constellations may be displayed.

Abstract: A medical analysis method for estimating a motion vector field of the magnitude and direction of local motion of lung tissue of a subject is described. In one embodiment a first 3D image data set of the lung and a second 3D image data set is obtained. The first and second 3D image data sets correspond to images obtained during inspiration and expiration respectively. A rigid registration is performed to align the 3D image data sets with one another. A deformable registration is performed to match the 3D image data sets with one another. A motion vector field of the magnitude and direction of local motion of lung tissue is estimated based on the deforming step. The motion vector field may be computed prior to treatment to assist with planning a treatment as well as subsequent to a treatment to gauge efficacy of a treatment. Results may be displayed to highlight.

Abstract: A method and system for assisting a physician track a surgical device in a body organ of a subject during a procedure includes fluoroscopic based registration, tracking, and optimizing a fluoroscopy position. An initial registration step includes receiving a 3D image data of a subject in a first body position, receiving a real time fluoroscopy image data, and estimating a deformation model or field to match points in the real time fluoro image with a corresponding point in the 3D model. A tracking step includes computing the 3D location of the surgical device and displaying the surgical device and the 3D model of the body organ in a fused arrangement. Optimizing the fluoroscope camera pose includes computing a candidate camera pose to assist the surgeon to track a surgical device based on features of the surgical device, position of the patient, and mechanical properties or constraints of the fluoroscope.

Abstract: A system and method are described for determining candidate fiducial marker locations in the vicinity of a lesion. Imaging information and data are input or received by the system and candidate marker locations are calculated and displayed to the physician. Additionally, interactive feedback may be provided to the physician for manually selected or identified sites. The physician may thus receive automatic real time feedback for a candidate fiducial marker location and adjust or accept a constellation of fiducial marker locations. 3D renderings of the airway tree, lesion, and marker constellations may be displayed.

Abstract: A system and method employing image analysis may provide an objective measure of the state of gingival tissue health. A region of analysis on an image of gingival tissue may be divided into pixels. Each pixel may have an associated color made up of component R, G and B values. A user may obtain an objective measurement of oral cavity soft tissue health by determining an objective measurement of the component color values of a gingival tissue image region and performing statistical analysis on the color values.

Abstract: The present invention relates to use of a compound for promoting antiredeposition during laundering of a textile fabric, in which the compound is a polymer comprising a polysaccharide backbone substituted by one or more groups -L-R1, where L represents an ester, amide or ether linkage and R represents an anionic alkyl group or a salt thereof, which has a degree of substitution of from 0.005 to 1 and a degree of biodegradation of at least 60% in 28 days. The use of such polymers in the manufacture of a laundry cleaning composition is also provided as well as laundry cleaning compositions containing such polymers.

Abstract: A method and system for use with an endoscopic instrument determines anatomical properties of body lumen at various states. Lumen properties such as lumen diameter are identified in two or more states corresponding to, for example, an inflated or deflated state. The lumen states are registered with one another and the anatomical properties are identified in real time at the location of an endoscope or endoscopic instrument used with the endoscope. In one embodiment a diametrical range of an airway is identified in real time at the location of a bronchoscope.

Abstract: A method and system employing image analysis may provide an objective measure of property values related to hard tissue or teeth in the oral cavity. A region of analysis on an image of hard tissue may be divided into pixels. Each pixel may have an associated color characteristic (e.g., R, G and B, multispectral) which is used to quantify a hard tissue property value of interest (e.g., percent plaque coverage, L*a*b* tooth color, percent stain). Hard Tissues Regions of Interest may be divided into indexed registration cells that allow for combining and/or comparing property values between images on a localized cell-by-cell basis. Results of cell-level property value analyses may be displayed by color-coding hard tissue pixels of a display image.

Abstract: A method for gene shuffling to form a mutant or chimeric gene, the method comprising: (a) assigning one or more segments of one or more genes based on regions of encoded amino acid sequence; (b) amplifying the one or more assigned segments of the gene using primers specific for each segment; and (c) causing recombination of the one or more amplified segments to form a mutant or chimeric gene. An oligonucleotide primer suitable for use in gene shuffling, the primer having a non-degenerate core based on a segment or template of a gene to be amplified, and the core being flanked by both 5? and 3? degenerate ends.

Abstract: Apparatus and method for catheterized delivery or infusion of medication and anaesthesia are disclosed. The perforating catheter is first used to perforate the periodontal ligament and/or the cortical plate of bone tissue, and is then left in place and used as a catheter for insertion of a hypodermic needle of smaller gauge to deliver medication or anaesthesia to a target area. The perforator is a bevelled needle for drilling into the ligament or bone tissue. For drilling, the device comprises an adaptor which transmits the rotational movement from a dental hand piece or the like to the bevelled needle. A cap is also included for protecting the bevelled needle during storage of the device. The adaptor may have a rod which extends axially into the bevelled needle when the device is assembled for drilling. The rod is used to prevent the debris resulting from drilling from blocking the passage in the bevelled needle.

Abstract: The present invention relates to use of a compound for promoting antiredeposition during laundering of a textile fabric, in which the compound is a polymer comprising a polysaccharide backbone substituted by one or more groups -L-R1, where L represents an ester, amide or ether linkage and R represents an anionic alkyl group or a salt thereof, which has a degree of substitution of from 0.005 to 1 and a degree of biodegradation of at least 60% in 28 days. The use of such polymers in the manufacture of a laundry cleaning composition is also provided as well as laundry cleaning compositions containing such polymers.

Abstract: A system and method for the use of ultra high frequency RFID tags in conjunction with metal substrates, as well as substrates used to contain liquid. Briefly, an RFID isolator comprised of a material with complex magnetic permeability, used either by itself, or in combination with dielectric isolator material, is interposed between the RFID tag and the substrate. Alternatively, a material possessing at least two distinct dielectric constants is interposed between the RFID tag and the substrate, such that there is a high dielectric constant at the interface with the substrate, and a low dielectric constant at the interface with the RFID tag. This material can be a single material having a dielectric constant gradient, or alternatively, two or more separate layers, each with a uniform but different dielectric constant, sandwiched together.

Abstract: A method for producing a mutant gene encoding a functional gene product comprising: (a) introducing one or more mutations into a gene to form a mutated gene; (b) providing the mutated gene to a host microorganism; (c) culturing the host microorganism containing the mutated gene under conditions which allow expression of the mutant gene product; and (d) selecting a host microorganism capable of producing a functional gene production from the mutated gene.

Abstract: The present invention provides a system and method for optimizing the performance of 13.56 MHz frequency RFID tags in conjunction with metal substrates. Briefly, a thickness exists for each type of RFID isolator material at which the performance of a 13.56 MHz RFID tag is optimal when used with metal. Varying from this optimal value, in either the positive or negative direction adversely affects read distance. A method of determining this optimal thickness is disclosed, as well as an RFID tag or a substrate being used in conjunction with a material of this thickness.

Abstract: The present invention provides a system and method for optimizing the performance of 13.56 MHz frequency RFID tags in conjunction with metal substrates. Briefly, a thickness exists for each type of RFID isolator material at which the performance of a 13.56 MHz RFID tag is optimal when used with metal. Varying from this optimal value, in either the positive or negative direction adversely affects read distance. A method of determining this optimal thickness is disclosed, as well as an RFID tag or a substrate being used in conjunction with a material of this thickness.

Abstract: Dispensing system with at least one dispenser 1 for articles that are available to be dispensed, preferably in form of a mini bar, an administering system for billing articles and/or administering the stock of the articles to be dispensed, or at least an interface 6 to such an administering system, whereby said dispenser 1 comprises at least one store area 3. Said one store area 3 allows the simultaneous storing of several preferably different articles, whereby the articles can be removed and placed back after inspection by the customer. As long as the customer only inspects the articles he will not be charged for the selling price of the articles. The articles can be freely positioned on the store area 3, whereby said store area is monitored by a detection device which is able to detect at least after a certain time whether an article has been removed. This detection works independently from the positions in said store area occupied by remaining articles and occupied formally by said removed article.

Abstract: A system and method for the use of ultra high frequency RFID tags in conjunction with metal substrates, as well as substrates used to contain liquid. Briefly, an RFID isolator comprised of a material with complex magnetic permeability, used either by itself, or in combination with dielectric isolator material, is interposed between the RFID tag and the substrate. Alternatively, a material possessing at least two distinct dielectric constants is interposed between the RFID tag and the substrate, such that there is a high dielectric constant at the interface with the substrate, and a low dielectric constant at the interface with the RFID tag. This material can be a single material having a dielectric constant gradient, or alternatively, two or more separate layers, each with a uniform but different dielectric constant, sandwiched together.