Abstract: The present disclosure describes a treatment composition comprising a nanoparticle composition comprising nanoparticles functionalized with surface amine groups and a crosslinking composition comprising genipin. The disclosure also describes a kit comprising the treatment composition, and instructions for using the kit to crosslink the nanoparticles to a tissue graft. The treatment composition and kit can be used to crosslink nanoparticles to a tissue graft, and the resulting tissue graft can be used to replace defective tissue in a subject in need thereof.

Abstract: An illustrative control system for a precision agricultural implement includes a controller having a convolutional neural network, an imaging device, a plurality of sensors, and a plurality of actuators in communication with the controller, the controller configured for detecting and tracking objects of interest in a commodity field, such a commodity plants, and the plurality of actuators including a plurality of agricultural tool actuators the controller operates based on the detection and tracking of object of interest in the commodity field.

Abstract: A method of utilizing Wi-Fi based passive motion detection to deliver targeted advertising through a smart TV is provided. The system uses an agent in connection with the wireless access point that the Smart TV uses to access the internet to make motion determinations. The CSI data of the access point is analyzed to identify if a user is present, if the user is stationary, the previous location of the user, and the activity the user is currently engaged in. An advertisement may be selected based on a last visited location and activity. Such advertisements may further be delivered to more engaged viewers when the advertiser pays a higher rate.

Abstract: A tape for collecting tissue samples in a manner compatible with imaging in a transmission electron microscopy (TEM) system, includes a tape substrate having two side walls forming a trough. The trough is defined by a bottom surface of the tape substrate and internal surfaces of the side walls, with an open side therebetween. A support film is attached to a top surface of the tape substrate, and a plurality of apertures is spaced at predetermined locations along the length of the tape substrate, each aperture being covered by the support film. The tape includes a stacked configuration in which the tape substrate is wound in layers, the bottom surfaces of the side walls in one layer being in contact with the support film in an immediately adjacent layer. The apertures in the second layer are aligned within the trough of the first layer, between the side walls.

Abstract: Embodiments include assay devices within a single use, disposable cassette for biochemical assays with at least one fluid well and at least one capillary valve. The capillary valve in combination with motion of porous sheets within the assay leads to addition of liquid reagents at different times to the assay although a user adds the liquid reagents to the cassette simultaneously.

Abstract: Embodiments include a microphone assembly comprising an array microphone and a housing configured to support the array microphone and sized and shaped to be mountable in a drop ceiling in place of at least one of a plurality of ceiling tiles included in the drop ceiling. A front face of the housing includes a sound-permeable screen having a size and shape that is substantially similar to the at least one of the plurality of ceiling tiles. Embodiments also include an array microphone system comprising a plurality of microphones arranged, on a substrate, in a number of concentric, nested rings of varying sizes around a central point of the substrate. Each ring comprises a subset of the plurality of microphones positioned at predetermined intervals along a circumference of the ring.

Abstract: Embodiments allow for an auto-mixer to gate microphones on and off based on speech detection, without losing or discarding the speech received during the speech recognition period. An example method includes receiving and storing an input audio signal. The method also includes determining, based on a first segment of the input audio signal, that the input audio signal comprises speech, and determining a delay between the input audio signal and a corresponding output audio signal provided to a speaker. The method also includes reducing the delay, wherein reducing the delay comprises removing one or more segments of the stored input audio signal to create a time-compressed audio signal and providing the time-compressed audio signal as the corresponding output audio signal. The method also includes determining that the delay is less than a threshold duration, and responsively providing the input audio signal as the corresponding output audio signal.

Abstract: A tape for collecting tissue samples in a manner compatible with imaging in a transmission electron microscopy (TEM) system, includes a tape substrate having two side walls forming a trough. The trough is defined by a bottom surface of the tape substrate and internal surfaces of the side walls, with an open side therebetween. A support film is attached to a top surface of the tape substrate, and a plurality of apertures is spaced at predetermined locations along the length of the tape substrate, each aperture being covered by the support film. The tape includes a stacked configuration in which the tape substrate is wound in layers, the bottom surfaces of the side walls in one layer being in contact with the support film in an immediately adjacent layer. The apertures in the second layer are aligned within the trough of the first layer, between the side walls.

Abstract: Technologies for attestation techniques, systems, and methods for determining an individual's movement are provided. The individual's movement is determined by passive indoor positioning technology using channel state information (CSI). A first set of data associated with an impulse or frequency response determined using channel state information (CSI) may be received from a Wireless access point located in proximity to a monitored space. A second set of data may also be received from an Internet of Things (IoT) device located in proximity to the monitored space. The first set of data may be compared to the second set of data. A profile database may be updated to replace the first set of data with the second set of data when the first and second sets of data are different.

Abstract: The present invention relates to methods for purifying nucleic acids. In particular, the present invention relates to a method for separating guanine-rich oligonucleotides from quadruplex secondary structures formed from the oligonucleotides using monolithic anion exchange chromatography. Mobile phase parameters that control quadruplex formation and enable separation of the intact quadruplex from the single-strand oligonucleotide are also described.

Abstract: An apparatus comprises a switch, a current monitor, and a controller. During operation, the switch controls an amount of current through the load. The current monitor samples a magnitude of the current through the load, a magnitude of which varies over time during a time duration. Based on integrating the sample magnitudes of the current through the load over the time duration, the current monitor produces a current sense value. The current sense value is representative of an amount of current through the load. The controller controls an operational state of the switch based upon a comparison of the current sense value with respect to an over-current threshold value. For example, in response to detecting a condition in which the current sense value is greater than the overcurrent threshold value, the controller turns OFF (deactivates) the switch, reducing or eliminating delivery of current through the load.

Abstract: A microphone module comprises a housing, an audio bus, and a first plurality of microphones in communication with the audio bus. The microphone module further comprises a module processor in communication with the first plurality of microphones and the audio bus. The module processor is configured to detect the presence of an array processor in communication with the audio bus, detect the presence of a second microphone module in communication with the audio bus, and configure the audio bus to pass audio signals from both the first plurality of microphones and the second microphone module to the array processor.

Abstract: The invention relates to a single-use cassette assembly for use in a reusable solid dose formulation delivery actuator device. Such improvements permit delivery of at least one therapeutic or prophylactic compound, or a solid dose formulation including, for example, a vaccine comprising the same with improved safety and reliability. The invention further concerns an improved needle-free method for delivering at least one therapeutic compound or a formulation comprising the same.

Abstract: There is provided a sandscreen joint (110) capable of providing zonal isolation. The ends of the portion of the (110) are capable of extension on activation of the sandscreen (110), including transition areas (135), which are coated with an elastomer sleeve (134). On activation of the sandscreen (110), the sleeve (134) is pushed out into contact with the bore wall and serves to isolate the zone on one side of the activated sleeve (134) from the zone on the other side of the sleeve (134). Thus, the provision of the sleeve (134) on the activated sandscreen (110) may prevent fluid from flowing axially along the bore between the bore wall and sandscreen. This may serve to protect the weave at the transition area (135), preventing axial flow through the transition areas (135).

Abstract: A method of utilizing Wi-Fi based passive motion detection to deliver targeted advertising through a smart TV is provided. The system uses an agent in connection with the wireless access point that the Smart TV uses to access the internet to make motion determinations. The CSI data of the access point is analyzed to identify if a user is present, if the user is stationary, the previous location of the user, and the activity the user is currently engaged in. An advertisement may be selected based on a last visited location and activity. Such advertisements may further be delivered to more engaged viewers when the advertiser pays a higher rate.

Abstract: Embodiments include assay devices within a single use, disposable cassette for biochemical assays with at least one fluid well and at least one capillary valve. The capillary valve in combination with motion of porous sheets within the assay leads to addition of liquid reagents at different times to the assay although a user adds the liquid reagents to the cassette simultaneously.

Abstract: Expansion compensating structures are formed in redistribution layers of a wafer-level chip-scale integrated circuit package (WLCSP) or other IC package having a low-expansion substrate. The structures include micromechanical actuators designed and oriented to move solder bumps attached to them in the same direction and distance as a function of temperature as do pads to which they may be connected on a higher-expansion substrate such as a printed circuit board. Expansion compensated IC packages incorporating these expansion compensating structures are provided, as well as expansion compensated assemblies containing one or more of these IC packages. Methods of fabricating expansion compensated IC packages requiring minimal changes to existing commercial WLCSP fabrication processes are also provided. These devices and methods will result in assemblies having improved board-level reliability during thermal cycling, and allow the use of larger IC die sizes in WLCSP technology.

Abstract: Embodiments include an audio system comprising an audio device, a speaker, and a processor. The audio system is configured to receive data from one or more sensors corresponding to persons in a room and/or characteristics of a room, and responsively take action to modify one or more characteristics of the audio system, share the information with other systems or devices, and track data over time to determine patterns and trends in the data.

Abstract: Analog processors for solving various computational problems are provided. Such analog processors comprise a plurality of quantum devices, arranged in a lattice, together with a plurality of coupling devices. The analog processors further comprise bias control systems each configured to apply a local effective bias on a corresponding quantum device. A set of coupling devices in the plurality of coupling devices is configured to couple nearest-neighbor quantum devices in the lattice. Another set of coupling devices is configured to couple next-nearest neighbor quantum devices. The analog processors further comprise a plurality of coupling control systems each configured to tune the coupling value of a corresponding coupling device in the plurality of coupling devices to a coupling. Such quantum processors further comprise a set of readout devices each configured to measure the information from a corresponding quantum device in the plurality of quantum devices.

Abstract: The present invention provides a series of injectable bionanocomposites that may be delivered via injection to various tissue repair sites including myocardial infarction, intervertebral disc reconstruction, reconstruction of skeletal muscle, and musculoskeletal applications, urinary incontinence, adipose tissue engineering, and orthopedic applications such as osteoporosis, and meniscus and articular cartilage repair.