Patents by Inventor David A. Griffith

David A. Griffith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220209221
    Abstract: A composition of matter suitable for usage as a formative material for a lithium-sulfur battery cathode is provided. The composition of matter may include a carbon structure formed by multiple carbon particles interconnected to one another. Each carbon particle may include pores and exposed surfaces. In this way, an electrically conductive material (ECM) (e.g., silver and/or antimony) may be deposited in the pores and coated (e.g., conformally coated) on the exposed surfaces of respective carbon particles. In addition, at least some carbon particles may disintegrate and provide exposed surfaces prior to deposition of the ECM. For example, disintegrated carbon particles may have a greater surface-area-to-volume ratio than whole carbon particles, thereby providing an increased amount of surface area available for subsequent ECM deposition. In addition, in some aspects, an active material may be infiltrated in one or more carbon particles and pores.
    Type: Application
    Filed: March 18, 2022
    Publication date: June 30, 2022
    Applicant: LytEn, Inc.
    Inventors: Michael W. Stowell, Bryce H. Anzelmo, David Tanner, Bruce Lanning, Joe Griffith Cruz
  • Publication number: 20220183781
    Abstract: Techniques for operating a kinematic structure by manual motion of a link coupled to the kinematic structure include a system having a kinematic structure configured to support an instrument and a processor. The processor is configured to place the system in a clutching mode; transition the system from the clutching mode to a set-up mode in response to detecting a joint operation of the kinematic structure; while in the set-up mode, determine an input displacement of a link from an initial positional relationship relative to a portion of the kinematic structure to a displaced positional relationship relative to the portion of the kinematic structure; and while in the set-up mode and in response to the determined input displacement, drive the kinematic structure so that the link returns toward the initial positional relationship relative to the portion of the kinematic structure.
    Type: Application
    Filed: March 2, 2022
    Publication date: June 16, 2022
    Inventors: Paul GRIFFITHS, Paul MOHR, Nitish SWARUP, Michael COSTA, David LARKIN, Thomas COOPER, Michael HANUSCHIK
  • Publication number: 20220148718
    Abstract: A method, system, and computer program product for predictive maintenance. A method may include receiving operation data associated with one or more injection systems, wherein the operation data includes one or more operation parameters associated with one or more operations of the one or more injection systems: determining one or more prediction scores for the one or more injection systems based on the operation data, wherein the one or more prediction scores include one or more predictions of one or more operation failures or misuses for the one or more injection systems; and providing maintenance data associated with the one or more operation failures or misuses, wherein the maintenance data is based on the one or more prediction scores.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 12, 2022
    Inventors: Ralph Schriver, Arthur Uber, III, Janele Archibald, Matthew Brewer, Amy Strafford, Christopher Fiorentini, David Griffiths, Jacob Hartmann, Joseph Hulbert, Susan Michel, Janel Petrilli, Michael Pogozelec, Barry Skirble
  • Publication number: 20220074930
    Abstract: The present invention relates to a method for capturing a molecular target present in the aqueous phase of a water-in-oil emulsion, said method being based on the use of a binding system comprising (a) a surfactant bearing a functional moiety on its hydrophilic head group and (b) a chemoprobe that acts as a molecular staple between the functionalized surfactant and the molecular target and comprises at least two distinct domains namely (i) at least one capture moiety which is able to specifically bind the molecular target and (ii) at least one binding domain which is able to interact with the functional group of the surfactant through covalent or non-covalent interactions, directly or through a binding intermediary.
    Type: Application
    Filed: November 22, 2021
    Publication date: March 10, 2022
    Inventors: ALAIN WAGNER, SYLVAIN URSUEGUI, MICHAËL RYCKELYNCK, KETTY PERNOD, ANDREW DAVID GRIFFITHS
  • Patent number: 11268485
    Abstract: A fuel pump for an internal combustion engine comprising a barrel having a longitudinal axis that spans between a proximal end and a distal end and a central bore therein. A plunger is disposed at least partially in the central bore and is configured to move along the longitudinal axis. An annular seal assembly is arranged around the circumference of the plunger wherein the annular seal assembly includes a seal retainer housing and a first seal and the seal retainer housing also retains the proximal end of the barrel thereon to form a second seal wherein the first and the second seals reduce the fuel to oil transfer rate and the oil to fuel transfer rate. The plunger and barrel are configured to be removed from and re-assembled with the annular seal assembly to enable service of these parts and the fuel pump.
    Type: Grant
    Filed: August 10, 2020
    Date of Patent: March 8, 2022
    Assignee: Cummins Inc.
    Inventors: Roberto Medina Munoz, Matthew B. State, Samuel David Griffith Magnuson, Thomas M. Yeager
  • Publication number: 20220047816
    Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.
    Type: Application
    Filed: September 28, 2021
    Publication date: February 17, 2022
    Inventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, David Griffiths
  • Patent number: 11246558
    Abstract: Described is an in-scan phantom for use during an imaging procedure. The phantom can include at least one measuring insert and/or at least one measured insert. The measuring insert may have radiation detecting capabilities while the measured insert may include a radioactive material. Also described is an imaging modality system that includes an imaging modality and an in-scan phantom as well as methods of using the in-scan phantom for imaging a patient or performing a scout scan.
    Type: Grant
    Filed: December 11, 2019
    Date of Patent: February 15, 2022
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Kevin Cowan, David Griffiths, Ivana Kingston, Dzmitry Liushtyk, Matthew Hoiko, Roey Flor, Robert Redmond, Henry Hernaez, Sridhar Balasubramanian
  • Publication number: 20220025033
    Abstract: It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.
    Type: Application
    Filed: October 13, 2021
    Publication date: January 27, 2022
    Inventors: Alastair David Griffiths LAWSON, Daniel John LIGHTWOOD, Rebecca Jayne MUNRO, James Philip O'CONNELL, John Robert PORTER
  • Patent number: 11232862
    Abstract: A method, system, and computer program product for predictive maintenance. A method may include receiving operation data associated with one or more injection systems, wherein the operation data includes one or more operation parameters associated with one or more operations of the one or more injection systems; determining one or more prediction scores for the one or more injection systems based on the operation data, wherein the one or more prediction scores include one or more predictions of one or more operation failures or misuses for the one or more injection systems; and providing maintenance data associated with the one or more operation failures or misuses, wherein the maintenance data is based on the one or more prediction scores.
    Type: Grant
    Filed: August 18, 2018
    Date of Patent: January 25, 2022
    Assignee: BAYER HEALTCARE LLC
    Inventors: Ralph Schriver, Arthur Uber, III, Janele Archibald, Matthew Brewer, Amy Chaya, Christopher Fiorentini, David Griffiths, Jacob Hartmann, Joseph Hulbert, Susan Michel, Janel Petrilli, Michael Pogozelec, Barry Skirble
  • Patent number: 11219234
    Abstract: A method for making a liquid (e.g. water or oil)-based food ingredient, having grill flavour properties, comprises: combusting in the presence of oxygen, an intimate mixture of (i) 2-15 parts by weight smoke source and (ii) 1 part by weight flavour source, to generate smoke; and combining the smoke with a liquid carrier, yielding the food ingredient, wherein the flavour source comprises a lipid having an oleic acid content (whether free or esterified) of 20% or higher.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: January 11, 2022
    Assignee: PureSmoke Limited
    Inventors: Elena Cristea, Huw David Griffiths
  • Publication number: 20210362264
    Abstract: A method of fabricating of an object includes causing a first heat source to heat a feed material to form a melt pool of the feed material on a surface. The method further includes causing a second heat source to heat the melt pool on the surface to regulate grain formation of the feed material in the melt pool as the melt pool cools and solidifies on the surface to form at least a portion of the object. The method also includes causing the first heat source and the second heat source to move relative to the surface as the melt pool is formed and cooled.
    Type: Application
    Filed: May 20, 2020
    Publication date: November 25, 2021
    Inventors: Nathan A. Ashmore, Gary W. Coleman, David Griffiths, Michelangelo Mortello, Robert James Scudamore, Lei Xu
  • Publication number: 20210361253
    Abstract: Described is a method of providing an estimate of radiation dose received by a patient during an imaging scan performed by an imaging system. The method includes receiving patient information about the patient, receiving scan data generated during the imaging scan of the patient by the imaging system, creating a virtual dose model of the patient based upon the patient information and the scan data, receiving a selection of a region of interest of the patient, performing a dose simulation on the virtual dose model of the patient or a portion thereof, and determining, based upon an outcome of the dose simulation, an estimate of the radiation dose received within the region of interest. The imaging scan can be a partial imaging scan of a portion of the patient. Also provided is a system and software for carrying out this method.
    Type: Application
    Filed: April 8, 2019
    Publication date: November 25, 2021
    Inventors: David GRIFFITHS, Arthur UBER, III, Jacob AGRIS, Ting LU, Peter THOMPSON
  • Patent number: 11181521
    Abstract: The present invention relates to a method for capturing a molecular target present in the aqueous phase of a water-in-oil emulsion, said method being based on the use of a binding system comprising (a) a surfactant bearing a functional moiety on its hydrophilic head group and (b) a chemoprobe that acts as a molecular staple between the functionalized surfactant and the molecular target and comprises at least two distinct domains namely (i) at least one capture moiety which is able to specifically bind the molecular target and (ii) at least one binding domain which is able to interact with the functional group of the surfactant through covalent or non-covalent interactions, directly or through a binding intermediary.
    Type: Grant
    Filed: April 4, 2017
    Date of Patent: November 23, 2021
    Assignees: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CENTRE INTERNATIONAL DE RECHERCHE AUX FRONTIÈRES DE LA CHIMIE
    Inventors: Alain Wagner, Sylvain Ursuegui, Michael Ryckelynck, Ketty Pernod, Andrew David Griffiths
  • Patent number: 11174311
    Abstract: It has been demonstrated that certain compounds bind to TNF and stabilise a conformation of trimeric TNF that binds to the TNF receptor. Antibodies which selectively bind to complexes of such compounds with TNF superfamily members are disclosed. These antibodies may be used to detect further compounds with the same activity, and as target engagement biomarker.
    Type: Grant
    Filed: December 13, 2017
    Date of Patent: November 16, 2021
    Assignees: UCB BIOPHARMA SRL, SANOFI
    Inventors: Alastair David Griffiths Lawson, Daniel John Lightwood, Rebecca Jayne Munro, James Philip O'Connell, John Robert Porter
  • Publication number: 20210332034
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Application
    Filed: June 13, 2019
    Publication date: October 28, 2021
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, Edward L. Conn, John M. Curto, David J. Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Chris Limberakis, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Patent number: 11141535
    Abstract: A fluid injector system for delivering a multi-phase fluid injection to a patient and methods of fluid delivery is disclosed. Methods of creating and using a multi-aspect fluid path impedance model of the injector system are used. Modeling and adjustment of factors that affect impedance and prevent or reduce backflow, reduce the likelihood of fluid flow rate spikes and provide more accurate flow rates and mixing ratios of fluids may be repeated or happen essentially continuously during an injection. The adjustments may be determined before the injection or determined and/or adjusted during the injection. The determination may include sensor feedback commonly used in injectors such as pressure and position feedback as well as other sensors. In all cases, the user can be notified of adjustments through on-screen notices and/or through the recordation of the injection data by a control device of the injector at the conclusion of the injection.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: October 12, 2021
    Assignee: BAYER HEALTHCARE LLC
    Inventors: Arthur Uber, III, Chelsea Marsh, William Barone, Michael McDermott, Timothy Newing, Michael Spohn, Vince Delbrugge, Ralph Schriver, Kevin Cowan, Barry Tucker, Ronald Heller, David Griffiths, Matthew Schrauder
  • Publication number: 20210309734
    Abstract: The invention relates to antibody molecules having specificity for antigenic determinants of both IL-17A and IL-17F, therapeutic uses of the antibody molecules and methods for producing said antibody molecules.
    Type: Application
    Filed: December 15, 2020
    Publication date: October 7, 2021
    Inventors: Ralph Adams, Terence Seward Baker, Alastair David Griffiths Lawson
  • Publication number: 20210163455
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, and 7-aza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Application
    Filed: February 9, 2021
    Publication date: June 3, 2021
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, David James Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Yajing Lian, Chris Limberakis, Allyn T. Londregan, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Publication number: 20210166780
    Abstract: The present invention provides a method for generation of multi-domain proteins, more particular antibodies, with an improved native state colloidal stability.
    Type: Application
    Filed: June 5, 2019
    Publication date: June 3, 2021
    Inventors: Ralph ADAMS, James HEADS, Sebastian KELM, Alastair David Griffiths LAWSON
  • Publication number: 20210153513
    Abstract: Food for human consumption is smoked by providing smoke, removing one or more polycyclic aromatic hydrocarbons (PAHs) from the smoke and contacting the food with the treated smoke, or smoking the food and then removing the PAHs from the smoked food. PAH removal is selective, to remove the PAHs that contain 4 or more benzene rings, in particular without significantly changing the volatile profile of the smoked food. A selective filter is provided, as is apparatus comprising a smoke generator, a chamber in which to smoke food, and the selective filter, disposed between the smoke generator and the chamber.
    Type: Application
    Filed: November 30, 2020
    Publication date: May 27, 2021
    Inventors: Huw David Griffiths, David Allan Baines, Jane Ker Parker-Gray