Patents by Inventor David A. Griffith

David A. Griffith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230287873
    Abstract: A pumping assembly includes at least one removable unit barrel pumping assembly coupled to a housing of the pumping assembly. The pumping assembly further includes a drive member having a roller configured to engage a portion of the unit barrel pumping assembly during operation of the pumping assembly. The roller is configured to include a plurality of geometric shapes to distribute load forces during operation of the pumping assembly.
    Type: Application
    Filed: May 17, 2023
    Publication date: September 14, 2023
    Inventors: Donald J. Benson, Eric A. Benham, Ahmad M. Sabri, Samuel David Griffith Magnuson
  • Publication number: 20230278989
    Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.
    Type: Application
    Filed: January 25, 2023
    Publication date: September 7, 2023
    Applicants: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Steven HOWARD, Benjamin David CONS, Jeffrey David ST. DENIS, Charlotte Mary GRIFFITHS-JONES, Steven Douglas HISCOCK, Rhian Sara HOLVEY, Alan Richard BURNS, David COUSIN, Hannah Louise DEXTER, Guillaume François PARRA, John Paul WATTS, Robert JEWELL, Jennifer Ann STOCKWELL, Kim Louise HIRST, Isabelle Anne LEMASSON, David John NASH, James Daniel OSBORNE, Jonas Calleja PRIEDE, Nicholas Paul RICHARDS, Aaron Michael DUMAS, Brian Christopher BISHOP, David PARRY-JONES, Jeremy Peter SCOTT, Meenakshi Sundaram SHANMUGHAM, Peter Richard MULLENS, David Charles LATHBURY, Darren James DIXON, Matthew James GAUNT
  • Publication number: 20230235729
    Abstract: The present disclosure provides a high-pressure fuel pump having barrel sets comprising offset, opposing barrel units within the same plane and having plungers disposed therein. The high-pressure fuel pump further includes a camshaft having at least one offset lobe and a cam ring encircling the lobe and in contact with the plungers, which translate the rotational movement of the camshaft to longitudinal movement of the plungers, controlling inflow, compression, and outflow of fuel within the pump.
    Type: Application
    Filed: March 11, 2020
    Publication date: July 27, 2023
    Inventors: Eric A. Benham, Mustafa Utku Unal, Donald J. Benson, Samuel David Griffith Magnuson, Benjamin Scott Myser
  • Publication number: 20230181866
    Abstract: A humidification system can include a heater base, a chamber, and a breathing circuit. The heater base includes a heater plate positioned in a recessed region, and a heat conductive portion of the chamber is configured to contact the heater plate. The heater base includes a guard configured to control movement of the chamber into and out of the recessed region. The guard includes an anti-racking mechanism. The chamber includes an inlet port, an outlet port. A downward extension extends into the chamber from the inlet port, and a baffle is disposed at a lower end of the downward extension. A component of the breathing circuit can include a conduit hanging end cap for shipping and storage. The end cap can include a hanging component to allow the breathing circuit component to be hung from a medical stand. The system can detect when breathing circuits are connected in reverse.
    Type: Application
    Filed: October 12, 2022
    Publication date: June 15, 2023
    Inventors: John James JACKSON, Barry Shack MANON, Victor Rosales CORRALES, Stefan Leo VAN WORKUM, Michael John ANDRESEN, Stephen David EVANS, Mark Samuel HAMILTON, Paul Fleming BUCKLEY, Jason Allan KLENNER, Hamish OSBORNE, Samuel Graham BOGGS, James William STANTON, Joseph Nathaniel GRIFFITHS, Jonathan Andrew George LAMBERT, Nicholas Edward VAUGHAN, James Owen KEHOE, Francisco Ernesto DE LA PEÑA DE LA FUENTE, Nicholas James Michael MCKENNA, Rachael PORTER, Simon Mordechai STAM, David Robert KEMPS, Edwin Joseph LYONS, Madeleine Bess MARTIN, Ada Yiwen SHOU, Huang-Ku LIU
  • Publication number: 20230173172
    Abstract: A fluid injector system configured for use in administering at least one fluid to a patient, the fluid injector system including at least one image capture device configured for capturing image data in an environment surrounding the fluid injector system; and a control device comprising at least one processor programmed or configured to receive, with the at least one processor, the image data captured by the at least one image capture device; determine, with the at least one processor, whether the received image data comprises at least one predetermined characteristic; and perform, with the at least one processor, at least one action in response to determining whether the received image data comprises at least one predetermined char-acteristic.
    Type: Application
    Filed: November 23, 2020
    Publication date: June 8, 2023
    Inventors: CHRISTOPHER JUBIC, DANIEL MANZO, MICHAEL HAEGG, NICHOLAS DOOLITTLE, JOANNE HOENER, LINDA VAN ROOSMALEN, NOLAN ZINN, DAVID GRIFFITHS, ARTHUR UBER, III, LING YU HUNG, EDWARD PREM
  • Publication number: 20230167794
    Abstract: The present disclosure provides a high-pressure fuel pump including a barrel unit, a plunger, and a camshaft assembly having an eccentric cam lobe including a surface of the lobe. A follower is provided between the plunger and the surface of the lobe of the camshaft assembly to facilitate translation between the rotational movement of the camshaft assembly to axial movement of the plunger. The follower includes arcuate surfaces configured to mate with corresponding arcuate surfaces of the lobe of the cam shaft assembly and the plunger, respectively.
    Type: Application
    Filed: January 27, 2023
    Publication date: June 1, 2023
    Inventors: Samuel David Griffith Magnuson, Donald J. Benson, Matthew B. State, Eric A. Benham, Aleksandr E. Lesin, Karthik Sethuraman
  • Publication number: 20230157552
    Abstract: A system and method for promoting and safeguarding the wellbeing of patients in relation to a fluid injection may obtain patient data; determine, based on the patient data, an initial risk prediction for a patient for a fluid injection to be administered to the patient, the initial risk prediction including a probability that the patient experiences at least one adverse event in response to the fluid injection; provide, to a user device, before the fluid injection is administered to the patient, the initial risk prediction; determine, after the fluid injection is started, sensor data associated with the patient; determine, based on the sensor data determined after the fluid injection is started, a current risk prediction including a probability that the patient experiences the at least one adverse event in response to the fluid injection; and provide, to the user device, the current risk prediction.
    Type: Application
    Filed: April 30, 2021
    Publication date: May 25, 2023
    Inventors: JOHANNES ANTON THUERING, ARTHUR UBER, III, DAVID GRIFFITHS, MICHAEL MCDERMOTT, CHARLES LANG, LINDA VAN ROOSMALEN, BARRY SKIRBLE, ADAM CZIBUR, DANIEL MOORE, VINCENZO CARUSO, BRANDON CLARKE
  • Patent number: 11658477
    Abstract: A multi-port power converter includes a housing that includes a plurality of ports structured to electrically interface to a plurality of loads, the plurality of loads having distinct electrical characteristics. The multi-port power converter also includes a plurality of solid state components configured to provide selected electrical power outputs and to accept selected electrical power inputs and a plurality of solid state switches configured to provide selected connectivity between the plurality of solid state components and the plurality of ports.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: May 23, 2023
    Assignee: EATON INTELLIGENT POWER LIMITED
    Inventors: Martin Wayne Mensch, Brandon William Fisher, Robert Stephen Douglass, Austin Robert Zurface, Jeff Howard Urian, James David, Bharath Suda, Asheesh Soni, Karsten Gerving, Guido Vollmar, Gerd Schmitz, Christoph Bausch, Ute Molitor, Lutz Friedrichsen, Kai Schroeder, Julia Otte, Madeline Philipsohn, Norbert Roesner, Volker Lang, Johannes Meissner, Paolo D'Amico, Jalpa Shah, Meng Wang, Damrongrit Piyabongkarn, Niles Stephen Ramseyer, Dennis Dukaric, Matt Haylock, Justin Keith Griffiths
  • Publication number: 20230124938
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Application
    Filed: October 24, 2022
    Publication date: April 20, 2023
    Applicant: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, Matthew S. Dowling, David Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Gajendra Ingle, Wenhua Jiao, Chris Limberakis, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Publication number: 20230089011
    Abstract: A computing device obtains data indicating a topography for an area comprising water and receives an indication of an identified data object representing a stressor to the area or a first monitoring station configurable to monitor the stressor. The computing device also determines a location for the identified data object in the topography and selects one or more related data objects to be related to the identified data object by determining a classification indicating whether the identified data object operates in water and selecting the one or more related data objects based on the location and the classification. The computing device also generates one or more controls for monitoring the area based on the selected one or more related data objects.
    Type: Application
    Filed: September 15, 2022
    Publication date: March 23, 2023
    Inventors: Philip David Griffith, Andie Hodge, Amir Naveed Lyall, Kirby Ann Thomas, Srinivas Reddy Valisekkagari, Ryan Todd Wendt
  • Publication number: 20230074381
    Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
    Type: Application
    Filed: June 1, 2022
    Publication date: March 9, 2023
    Applicant: UCB Biopharma SRL
    Inventors: Helene Margaret Finney, Alastair David Griffiths Lawson, Stevan Graham Shaw, Bryan John Smith, Kerry Louise Tyson, Lara Kevorkian, Christoph Meier, Kaushik Sarkar, Paul Alan Atherfold
  • Publication number: 20230026713
    Abstract: The present invention generally relates to systems and methods to create stable emulsions with low rates of exchange of molecules between microdroplets.
    Type: Application
    Filed: September 29, 2022
    Publication date: January 26, 2023
    Inventors: Felix Kleinschmidt, Andrew David Griffiths, Francois Caron, Abdeslam El Harrak, Eric Brouzes, Darren Roy Link
  • Patent number: 11551211
    Abstract: A virtual payment system for paying for goods, services and content ordered over an internetwork is disclosed. The virtual payment system includes a commerce gateway. Buyers and sellers becomes registered participants by applying for virtual payment buyer and seller accounts. Once an account is established with the commerce gateway, a digital certificate is stored on the registered participant's computer. A buyer can then order a product, i.e., goods, services or content from a seller and charge it to the virtual payment account. When the product is shipped, the seller notifies the commerce gateway, which applies the charges to the buyer's virtual payment account. The buyer can settle the charges using a prepaid account, a credit account, or by using reward points earned through use of the virtual payment account. A buyer may create sub-accounts.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: January 10, 2023
    Assignee: STRIPE, INC.
    Inventors: Robin B. Hutchison, Robert J. Llewellyn, Andre F. Viljoen, David Griffiths, Jr., David Birch, Iain M. Begg
  • Patent number: 11541540
    Abstract: A computer readable medium causing a computer to planning of a trajectory for an object that is capable of controlled movement in one or more degrees of freedom. At least one ordered sequence of movement profiles is obtained. The at least one ordered sequence includes: (i) movement profiles that end with a phase of increasing acceleration and (ii) movement profiles that end with a phase of decreasing acceleration. The ordered sequence is evaluated to select a movement profile capable of achieving a desired state of movement. The trajectory of the object is planned based on the selected movement profile.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: January 3, 2023
    Assignee: GLOWBUZZER LTD
    Inventors: David Griffiths, Alexander Kirkpatrick Kirkpatrick, Angela Gibson
  • Patent number: 11525826
    Abstract: The present invention relates to the field of biological diagnosis in oncology. It relates to a method and apparatus for detecting and/or characterizing tumor cells by detecting one or more elements of the tumor cell secretome, in particular one or more peptides or proteins, and, in particular, one or more tumor markers. The invention also relates to detecting and/or characterizing droplets of tumor cells and their method of preparation.
    Type: Grant
    Filed: April 18, 2017
    Date of Patent: December 13, 2022
    Assignees: Chu Montpellier, Ecole Superieure De Physique Et De Chimie Industrielles De La Ville De Paris, Centre National De La Recherche Scientifique, Université De Montpellier, Axlr, Satt Du Languedoc Roussillon
    Inventors: Catherine Michèle Marilou Alix-Panabieres, Andrew David Griffiths, Raphaël Clément Li-Ming Doineau, Clément Nizak, Philippe Chi-Thanh Nghe, Jean-Marie Pierre Baudry, Elodie Michèle Christine Brient-Litzler, Klaus Eyer, Jérôme Bibette
  • Patent number: 11512070
    Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: November 29, 2022
    Assignee: Pfizer Inc.
    Inventors: Gary Erik Aspnes, Scott W. Bagley, John M. Curto, Matthew S. Dowling, David Edmonds, Mark E. Flanagan, Kentaro Futatsugi, David A. Griffith, Kim Huard, Gajendra Ingle, Wenhua Jiao, Chris Limberakis, Alan M. Mathiowetz, David W. Piotrowski, Roger B. Ruggeri
  • Publication number: 20220362771
    Abstract: An aspect of the invention relates to a method for the diagnosis and/or prognosis of drug resistance, wherein single cell chromatin states are profiled in cells obtained from a subject by using a microfluidic system.
    Type: Application
    Filed: July 12, 2019
    Publication date: November 17, 2022
    Inventors: Annabelle Patricia Veronique GERARD, Kevin Armand GROSSELIN, Andrew David GRIFFITHS, Céline Victoire Delphine Marie VALLOT
  • Patent number: 11423400
    Abstract: A virtual payment system for paying for goods, services and content ordered over an internetwork is disclosed. The virtual payment system includes a commerce gateway. Buyers and sellers becomes registered participants by applying for virtual payment buyer and seller accounts. Once an account is established with the commerce gateway, a digital certificate is stored on the registered participant's computer. A buyer can then order a product, i.e., goods, services or content from a seller and charge it to the virtual payment account. When the product is shipped, the seller notifies the commerce gateway, which applies the charges to the buyer's virtual payment account. The buyer can settle the charges using a prepaid account, a credit account, or by using reward points earned through use of the virtual payment account. A buyer may create sub-accounts.
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: August 23, 2022
    Assignee: STRIPE, INC.
    Inventors: Robin B. Hutchison, Robert J. Llewellyn, Andre F. Viljoen, David Griffiths, Jr., David Birch, Iain M. Begg
  • Publication number: 20220227380
    Abstract: Techniques for performing a sensor calibration using sequential data is disclosed. An example method includes receiving, from a first camera located on a vehicle, a first image comprising at least a portion of a road comprising lane markers, where the first image is obtained by the camera at a first time; obtaining a calculated value of a position of an inertial measurement (IM) device at the first time; obtaining an optimized first extrinsic matrix of the first camera by adjusting a function of a first actual pixel location of a location of a lane marker in the first image and an expected pixel location of the location of the lane marker; and performing autonomous operation of the vehicle using the optimized first extrinsic matrix of the first camera when the vehicle is operated on another road or at another time.
    Type: Application
    Filed: January 15, 2021
    Publication date: July 21, 2022
    Inventors: Shane David GRIFFITH, Chenghao GONG, Chenzhe QIAN
  • Patent number: 11384148
    Abstract: The disclosure relates to antibodies specific to FcRn, formulations comprising the same, use of each in therapy, processes for expressing and optionally formulating said antibody, DNA encoding the antibodies and hosts comprising said DNA.
    Type: Grant
    Filed: February 8, 2019
    Date of Patent: July 12, 2022
    Inventors: Helene Margaret Finney, Alastair David Griffiths Lawson, Stevan Graham Shaw, Bryan John Smith, Kerry Louise Tyson, Lara Kevorkian, Christoph Meier, Kaushik Sarkar, Paul Alan Atherfold