Abstract: Compounds of the general formula I and physiologically acceptable acid addition salts thereof:- ##STR1## in which R.sup.1 is a lower alkyl, lower alkenyl, or arylalkyl radical, which radicals may optionally be substituted by one or more alkoxy or hydroxy groups.R.sup.2 represents a hydrogen atom or a lower alkyl radical which may optionally be substituted by one or more hydroxy groups, amino groups, or heterocyclic rings containing one or more heteroatoms, or R.sup.2 represents a cycloalkyl, arylalkyl or aryloxyalkyl radical, which radicals may optionally be substituted by one or more alkoxy or hydroxy groups;R.sup.3 represents a hydrogen atom or a benzyl group;X represents a group of formula --CONR.sup.4 R.sup.5 where R.sup.4 and R.sup.5 may be the same or different and each represents hydrogen or a lower alkyl group;With the proviso that when R.sup.2 is tertiary butyl and R.sup.1 is a benzyl group, R.sup.3 represents a hydrogen atom. The compounds have a blocking action on .beta.

Abstract: Herbicidal formulations are provided utilizing as active ingredient, 4-hydroxy-2,3,5,6-tetrahalopyridines and salts thereof.

Abstract: Compounds of the formula ##STR1## in which: R.sub.4 and R.sub.5 independently represent hydrogen or lower alkyl;R.sub.6 represents a group Y(CH.sub.2).sub.n, in which n is 2 or 3 andY represents a straight or branched chain alkyl group containing 5 carbon atoms optionally substituted with one more hydroxy or alkoxy groups or by aryl groups which may, in turn, contain hydroxy or alkoxy substituents; orY represents a group ZO--, in which Z represents a straight or branched alkyl group containing from 2 to 6 carbon atoms inclusive substituted by one or more alkoxy, hydroxy, or aryloxy groups; or Z represents an aryl group which may, optionally, contain one or more hydroxy or alkoxy substituents; andR.sub.7 represents a straight or branched alkyl group containing from 3 to 6 carbon atoms, inclusive, optionally substituted by an aryl or aryloxy group which aryl or aryloxy group may, in turn be substituted by hydroxy and alkoxy groupsAnd pharmaceutically acceptable salts thereof.

Abstract: Compounds of the general formula: ##SPC1##In which:R.sub.1 and R.sub.2 which may be the same or different, represent a hydrogen atom or an alkyl group which may optionally be substituted by an aryl group, or represents an alkanoyl, aroyl or alkanesulphonyl group;R.sub.3 represents a hydrogen atom, or an alkyl group which may optionally be substituted by an aryl group, or represents an alkenyl, aryl or alkylthio group;R.sub.4 represents a hydrogen atom or an alkyl group; andR.sub.5 represents a hydrogen atom or an aryl or alkyl group, which alkyl group may optionally be substituted by a cycloalkyl group;And physiologically acceptable salts and derivatives thereof and addition products formed by nucleophilic addition.These compounds act as spasmolytics and phosphodiasterase inhibitors and have cardiotonic and diuretic properties. They are also of use in the treatment of skin disorders and gout.