Abstract: Silicone urethane (meth)acrylates can have at least three (meth)acrylate groups and not more urethane groups than (meth)acrylate groups. A method for preparing the silicone urethane (meth)acrylates involves reacting at least one hydroxy functional silicone (meth)acrylate with at least one isocyanate functional urethane (meth)acrylate. Compositions can contain the silicone urethane (meth)acrylates, and are useful for the production of release coatings, protective films, and protective coatings; and for the manufacturing of 3D printed objects by stereolithography.

Abstract: A process for converting a first hydrocarbon feed stream to one or more liquid transportation fuels in a petroleum refinery where the feed stream is analyzed by at least one analytical method to produce data that is transformed to wavelet coefficients data. A pattern recognition algorithm is trained to recognize subtle features in the wavelet coefficients data that are associated with an attribute of the feed stream. The trained pattern recognition algorithm then rapidly classifies potential hydrocarbon feed streams as a member of either a first group or a second group where the second group comprises hydrocarbon feed streams where the attribute or chemical characteristic at or above a predetermined threshold value. This classification allows rapid decisions to be made regarding utilization of the feedstock in the refinery that may include altering at least one variable in the operation of the refinery.

Abstract: A process for converting a first hydrocarbon feed stream to one or more liquid transportation fuels in a petroleum refinery where the feed stream is analyzed by at least one analytical method to produce data that is transformed to wavelet coefficients data. A pattern recognition algorithm is trained to recognize subtle features in the wavelet coefficients data that are associated with an attribute of the feed stream. The trained pattern recognition algorithm then rapidly classifies potential hydrocarbon feed streams as a member of either a first group or a second group where the second group comprises hydrocarbon feed streams where the attribute or chemical characteristic at or above a predetermined threshold value. This classification allows rapid decisions to be made regarding utilization of the feedstock in the refinery that may include altering at least one variable in the operation of the refinery.

Abstract: A process for producing liquid transportation fuels in a petroleum refinery while preventing or minimizing corrosion of refinery process equipment. Spectral data selected from mid-infrared spectrometry, nuclear magnetic resonance spectrometry, or both is obtained and converted to wavelets coefficients data. A pattern recognition genetic algorithm is then trained to recognize subtle features in the wavelet coefficients data to allow classification of crude samples into one of two groups based on corrosion propensity. One of several actions is taken depending upon the measured corrosion propensity of the potential feed stock in order to prevent or minimize corrosion while producing one or more liquid hydrocarbon fuels.

Abstract: A process for producing liquid transportation fuels in a petroleum refinery while avoiding the usage of crude oil feed stock that characterized by a fouling thermal resistance having the potential to foul refinery processes and equipment. Spectral data selected from NIR, NMR or both is obtained and converted to wavelets coefficients data. A genetic algorithm (or support vector machines) is then trained to recognize subtle features in the wavelet coefficients data to allow classification of crude samples into one of two groups based on fouling potential. Rapid classification of a potential crude oil feed stock according to its fouling potential prevents the utilization of feed stocks characterized by increased fouling potential in a petroleum refinery to produce liquid transportation fuels.

Abstract: A process for producing liquid transportation fuels in a petroleum refinery while avoiding the usage of crude oil feed stock that characterized by a fouling thermal resistance having the potential to foul refinery processes and equipment. Spectral data selected from NIR, NMR or both is obtained and converted to wavelets coefficients data. A genetic algorithm (or support vector machines) is then trained to recognize subtle features in the wavelet coefficients data to allow classification of crude samples into one of two groups based on fouling potential. Rapid classification of a potential crude oil feed stock according to its fouling potential prevents the utilization of feed stocks characterized by increased fouling potential in a petroleum refinery to produce liquid transportation fuels.

Abstract: Compounds of Formula (I): and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4 and R5 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases and pain.

Abstract: This invention provides compounds of Formula I wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.

Abstract: This invention provides compounds of Formula I wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.

Abstract: Compounds of Formula (I): and pharmaceutically acceptable salts thereof in which R1, R2, R3, R4 and R5 have the meanings given in the specification, are inhibitors of cFMS and are useful in the treatment of bone-related diseases, cancer, autoimmune disorders, inflammatory diseases, cardiovascular diseases and pain.

Abstract: This invention provides compounds of Formula I wherein B, G, A, E, R1, R2, R3, m and n are as defined herein, which are useful as type I receptor tyrosine kinase inhibitors, and methods of use thereof in the treatment of hyperproliferative disorders in mammals.

Abstract: The present invention relates to phenylurea derivatives of capreomycin I, IIB, IIA, or IB, and metabolites and pharmaceutically acceptable salts and solvates thereof. The compounds of the present invention are useful as antibacterial agents for treating bacterial infections and for treating disorders caused by bacterial infections. The present invention also relates to pharmaceutical compositions containing such compounds and to methods of treating bacterial infections by administering such compounds. The present invention also relates to methods of preparing such compounds.

Abstract: Provided is a dynamic resolution method of enriching a desired isomer of an alpha-substituted carboxylic acid relative to an undesired isomer, the method comprising: (a) in a solvent, contacting the alpha-substituted carboxylic acid, wherein the alpha substitution is with a leaving group and wherein the alpha carbon is chiral, with a homochiral amine to form a salt that is partially insoluble under selected reaction conditions, wherein the homochiral amine is selected so that the solubility of the amine salt of the undesired alpha-substituted carboxylic acid is greater than that of the amine salt of the desired alpha-substituted carboxylic acid under the selected reaction conditions; (b) reacting under the selected reaction conditions the salt with a nucleophile, wherein the reacting is effective in producing a net increase in the less soluble amine salt of the alpha-substituted carboxylic acid, and wherein the selected conditions are selected to (i) promote nucleophilic substitution of the nucleophile and th

Abstract: This invention is an improved method and device for treating varicose veins 200 or the greater saphenous vein 202. The method comprises the use of infrared laser radiation in the region of 1.2 to 2.2 um in a manner from inside the vessel 200 or 202 such that the endothelial cells of the vessel wall 704 are damaged and collagen fibers in the vessel wall 704 are heated to the point where they permanently contract, the vessel 200 or 202 is occluded and ultimately resorbed. The device includes a laser 102 delivering laser energy via a fiber optic catheter 300. A motorized pull back device 104 may be used. The laser is preferably operated under laser energy delivery conditions that substantially prevent the formation of coagulum on the energy emitting tip of the fiber.

Abstract: A method and apparatus that will alter the fibrous strands in the fatty layers of the skin to reduce the appearance of cellulite and adipose tissue. Electromagnetic energy is used to selectively shrink or alternatively photoacoustically ablate the collagen in the constricting bands of connective tissue that causes the dimpled appearance of cellulite and adipose tissue while avoiding damage to the surrounding fatty cells.

Abstract: A method and apparatus that will alter the fibrous strands in the fatty layers of the skin to reduce the appearance of cellulite and adipose tissue. Electromagnetic energy is used to selectively shrink or alternatively photoacoustically ablate the collagen in the constricting bands of connective tissue that causes the dimpled appearance of cellulite and adipose tissue while avoiding damage to the surrounding fatty cells.

Abstract: Improved devices and methods for removing blood from a blood vessel in preparation for endovenous laser ablation are described. The improved methods include one or more of: placing the patient in the Trendelenburg position, applying external compression around the vein, massaging the vein, cooling the vein externally, encouraging spasming of the vein, and removing blood with a suction device.

Abstract: A method and apparatus for treatment of skin or other tissue, using a source of thermal, electromagnetic radiation, electrical current, ultrasonic, mechanical or other type of energy, to cause minimally-invasive thermally-mediated effects in skin or other tissue which stimulates a wound-healing response, in conjunction with topical agents or other wound healing compositions, for application on the skin or other tissue which accelerate collagenesis, such as in response to wound healing. The dosage and time period of application of the compositions are adjusted to prevent external or surface tissue damage.

Abstract: A method and apparatus that will alter the fibrous strands in the fatty layers of the skin to reduce the appearance of cellulite. Electromagnetic energy is used to selectively shrink or alternatively loosen the collagen in the constricting bands of connective tissue that causes the dimpled appearance of cellulite while avoiding damage to the surrounding fatty cells.

Abstract: A method and device to treat superficial lesions in the skin such as solar lentigines that involves a light based energy delivery system in conjunction with a pulsed cooling device to selectively heat surface targets without damage to deeper skin structures.