Patents by Inventor David A. Juergens

David A. Juergens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for updating a map of the surrounding area, device for executing method steps of said method on the vehicle, vehicle, device for executing method steps of the method on a central computer, and computer-readable storage medium
    Patent number: 11940291
    Abstract: A method for updating a map of the surrounding area wherein the map is used when controlling a transportation vehicle. The transportation vehicle attempts, when travelling along a carriageway, to detect a landmark recorded in the map of the surrounding area using sensors. In response to the transportation vehicle being unable to detect the landmark using its sensors, the transportation vehicle prepares a proposal for deletion which is sent to an external central computer. The proposal for deletion is examined in the external central computer and deletes the landmark from the map of the surrounding area in response to the proposal for deletion being verified. In the method, information regarding a visibility range for the landmark is entered in the map of the surrounding area specifying at what range the landmark is visible from a road permitting a more effective detection of landmarks.
    Type: Grant
    Filed: July 25, 2019
    Date of Patent: March 26, 2024
    Assignee: VOLKSWAGEN AKTIENGESELLSCHAFT
    Inventors: Daniel Wilbers, Christian Merfels, Bernd Rech, Thilo Schaper, Niklas Koch, Stefan Jürgens, David Perdomo Lopez, Constanze Hungar
  • PHARMACEUTICAL COMPOSITION, METHODS FOR TREATING AND USES THEREOF
    Publication number: 20240091245
    Abstract: The present invention relates to certain SGLT-2 inhibitors for treating, preventing, protecting against and/or delaying the progression of chronic kidney disease in patients, for example patients with prediabetes, type 1 or type 2 diabetes mellitus.
    Type: Application
    Filed: November 21, 2023
    Publication date: March 21, 2024
    Inventors: Uli Christian BROEDL, Odd-Erik JOHANSEN, Eric Williams MAYOUX, Nima SOLEYMANLOU, Maximilian von EYNATTEN, Hans-Juergen WOERLE, David Z.I. CHERNEY, Bruce A. PERKINS
  • Pharmaceutical composition, methods for treating and uses thereof
    Patent number: 11918596
    Abstract: The present invention relates to certain SGLT-2 inhibitors for treating and/or preventing oxidative stress, for example in patients with type 1 or type 2 diabetes, as well as to the use of such SGLT-2 inhibitors in treatment and/or prevention of cardiovascular diseases in patients, for example type 1 or type 2 diabetes patients. The present invention further relates to certain SGLT-2 inhibitors for treating and/or preventing a metabolic disorder and preventing, reducing the risk of or delaying the occurrence of a cardiovascular event in patients, for example patients with type 1 or type 2 diabetes.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: March 5, 2024
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Uli Christian Broedl, Odd-Erik Johansen, Gabriel Woojai Kim, Eric Williams Mayoux, Afshin Salsali, Nima Soleymanlou, Maximilian von Eynatten, Hans-Juergen Woerle, David Z. I. Cherney, Bruce A. Perkins, Andreas Daiber, Thomas Muenzel
  • Scaffolding protein functional sites using deep learning
    Publication number: 20230416726
    Abstract: De novo designed proteins with binding activity are disclosed, which were designed starting from a desired functional site and jointly filling in the missing sequence and structure needed to complete the protein, and uses of the binding proteins.
    Type: Application
    Filed: June 22, 2023
    Publication date: December 28, 2023
    Inventors: David BAKER, Jue WANG, Robert RAGOTTE, Lukas MILLES, Joseph L. WATSON, David JUERGENS, Sidney LISANZA, Amijai SARAGOVI, Wei YANG, Derrick HICKS, Douglas TISCHER, Thomas SCHLICHTHAERLE
  • CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20230139321
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Application
    Filed: May 20, 2022
    Publication date: May 4, 2023
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • Chemokine receptor modulators and uses thereof
    Patent number: 11384064
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: July 12, 2022
    Assignee: RAPT Therapeutics, Inc.
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • Chemokine receptor modulators and uses thereof
    Patent number: 11192879
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Grant
    Filed: April 27, 2020
    Date of Patent: December 7, 2021
    Assignee: RAPT THERAPEUTICS, INC.
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF
    Publication number: 20210317134
    Abstract: Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
    Type: Application
    Filed: March 5, 2020
    Publication date: October 14, 2021
    Inventors: Jacob Bradley Schwarz, John Michael Ketcham, Maureen Kay Reilly, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, David Juergen Wustrow, Emily Karbarz, Xinping Han, Grant Shibuya, Jack Maung, Maksim Osipov
  • Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof
    Patent number: 11084829
    Abstract: Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
    Type: Grant
    Filed: September 20, 2019
    Date of Patent: August 10, 2021
    Assignee: RAPT THERAPEUTICS, INC.
    Inventors: Berenger Biannic, Xinping Han, Dennis X. Hu, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, David Juergen Wustrow, Kyle Young, Gene Cutler, Yamini Ohol-Gupta
  • CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20200339539
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Application
    Filed: April 27, 2020
    Publication date: October 29, 2020
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20200325117
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Application
    Filed: April 27, 2020
    Publication date: October 15, 2020
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20200239480
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of CCR4 activity.
    Type: Application
    Filed: January 28, 2020
    Publication date: July 30, 2020
    Inventors: Hilary Plake Beck, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, John Michael Ketcham, Jay Patrick Powers, Maureen Kay Reilly, Omar Robles-Resendiz, Hunter Paul Shunatona, James Ross Walker, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky, Jeffrey J. Jackson
  • Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof
    Patent number: 10722514
    Abstract: Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: July 28, 2020
    Assignee: RAPT THERAPEUTICS, INC.
    Inventors: Berenger Biannic, Xinping Han, Dennis X. Hu, John Michael Ketcham, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, Grant Shibuya, David Juergen Wustrow, Kyle Young
  • Chemokine receptor modulators and uses thereof
    Patent number: 10683280
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: June 16, 2020
    Assignee: RAPT THERAPEUTICS, INC.
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • Chemokine receptor modulators and uses thereof
    Patent number: 10604526
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of CCR4 activity.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: March 31, 2020
    Assignee: RAPT THERAPEUTICS, INC.
    Inventors: Hilary Plake Beck, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, John Michael Ketcham, Jay Patrick Powers, Maureen Kay Reilly, Omar Robles-Resendiz, Hunter Paul Shunatona, James Ross Walker, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky, Jeffrey J. Jackson
  • UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF
    Publication number: 20200095260
    Abstract: Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
    Type: Application
    Filed: September 20, 2019
    Publication date: March 26, 2020
    Inventors: Berenger Biannic, Xinping Han, Dennis X. Hu, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, David Juergen Wustrow, Kyle Young, Gene Cutler, Yamini Ohol-Gupta
  • CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20190233397
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of certain chemokine receptor activity.
    Type: Application
    Filed: January 24, 2019
    Publication date: August 1, 2019
    Inventors: Jeffrey J. Jackson, John Michael Ketcham, Akinori Okano, Maureen Kay Reilly, Omar Robles-Resendiz, Jacob Bradley Schwarz, Parcharee Tivitmahaisoon, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky
  • CHEMOKINE RECEPTOR MODULATORS AND USES THEREOF
    Publication number: 20190152978
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of CCR4 activity.
    Type: Application
    Filed: November 19, 2018
    Publication date: May 23, 2019
    Inventors: Hilary Plake Beck, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, John Michael Ketcham, Jay Patrick Powers, Maureen Kay Reilly, Omar Robles-Resendiz, Hunter Paul Shunatona, James Ross Walker, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky, Jeffrey J. Jackson
  • UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF
    Publication number: 20190142834
    Abstract: Disclosed herein, inter alia, compounds and methods of use thereof for the modulation of USP7 activity.
    Type: Application
    Filed: November 13, 2018
    Publication date: May 16, 2019
    Inventors: Berenger Biannic, Xinping Han, Dennis X. Hu, John Michael Ketcham, Paul Robert Leger, Jack Maung, Akinori Okano, Jacob Bradley Schwarz, Grant Shibuya, David Juergen Wustrow, Kyle Young
  • Chemokine receptor modulators and uses thereof
    Patent number: 10246462
    Abstract: Disclosed herein, inter alia, are compounds and methods of use thereof for the modulation of chemokine receptor activity.
    Type: Grant
    Filed: September 8, 2017
    Date of Patent: April 2, 2019
    Assignee: FLX BIO, INC.
    Inventors: Hilary Plake Beck, Berenger Biannic, Minna Hue Thanh Bui, Dennis X. Hu, Jeffrey J. Jackson, John Michael Ketcham, Jay Patrick Powers, Maureen Kay Reilly, Omar Robles-Resendiz, Hunter Paul Shunatona, James Ross Walker, David Juergen Wustrow, Ashkaan Younai, Mikhail Zibinsky