Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: Provided herein are compounds of the Formula (I): (I) and tautomers, stereoisomers and pharmaceutically acceptable salts and solvates thereof, wherein Rx, Ry, W, X, Y, Z, Ring A and (AA) have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Abstract: The present disclosure provides devices, systems and methods for mapping of traffic boundaries.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: Systems and methods for curating video and other driving-related data for use in driver coaching, which may include selecting or ranking driving behaviors for coaching, selecting or ranking drivers for coaching, selecting or ranking video and other data to be used in coaching, preparing for, scheduling, and summarizing coaching sessions, matching the format of coaching to the behavior or person being coached, preventing unsafe driving situations, influencing job dispatch decisions based on safety scores, and/or reducing data bandwidth usage based on a determined coaching effectiveness of video data.

Abstract: Systems, computer program products, and methods are described herein for de-conflicting data labeling in real-time deep learning systems. The present invention is configured to retrieve one or more dynamically generated expert profiles; and determine an optimal expert mix of experts to classify the transaction into a transaction types, wherein the expert profiles comprises: (i) shared information metrics, (ii) divergence metrics, (iii) characteristics associated with the one or more experts, (iv) a predictive accuracy of the one or more experts, (v) an exposure score associated with the one or more experts, and (vi) information associated with the transaction, wherein the optimal expert mix comprises: (i) a best expert for classifying the transaction, (ii) a combination score from at least the portion of the one or more experts evaluating the transaction simultaneously, and (iii) a sequence of at least the portion of the one or more experts analyzing the transaction.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: Systems and methods are provided for determining cause of atypical traffic events and/or encouraging good driving behavior. The systems and methods may involve a camera sensor and/or inertial sensors to detect traffic events, as well analytical methods that may attribute a cause to the traffic event. The systems and methods include a processor that is configured to determine an occurrence of an atypical traffic event at or near a monitored vehicle; and determine a cause of the atypical traffic event based on data collected at the monitored vehicle, wherein the cause of the atypical traffic event is at least one of: a driver or control system of the monitored vehicle; a second driver or second control system of a second vehicle; and a road condition.

Abstract: Systems and methods are provided for detecting a driving action that mitigates risk.

Abstract: Systems and methods are provided for intelligent driving monitoring systems, advanced driver assistance systems and autonomous driving systems, and providing one-click driver image labeling to facilitate the assignment of drive time to a driver. Various aspects of the driver and/or passengers may be determined, which may include a driver identifier previously associated with the driver, whether the driver is wearing a facial covering, whether an image of the driver is partially occluded, whether the driver is facing in the direction of the camera, and whether an image of the driver is expected to be easily recognizable to a person tasked with assigning representative driver images to driver identifiers. These determinations may be used to improve the efficacy and ease-of-use of a visual login system.

Abstract: Systems and methods are provided for determining cause of atypical traffic events and/or encouraging good driving behavior. The systems and methods may involve a camera sensor and/or inertial sensors to detect traffic events, as well analytical methods that may attribute a cause to the traffic event. The systems and methods include a processor that is configured to determine an occurrence of an atypical traffic event at or near a monitored vehicle; and determine a cause of the atypical traffic event based on data collected at the monitored vehicle, wherein the cause of the atypical traffic event is at least one of: a driver or control system of the monitored vehicle; a second driver or second control system of a second vehicle; and a road condition.

Abstract: Systems and methods are provided for detecting a driving action that mitigates risk.

Abstract: Systems and methods are provided for recording video of a driver in a vehicle and a surrounding visual field of the driver. The system includes a detachable body coupled to a windshield of a vehicle. The system further includes three or more cameras coupled to the detachable body. The three or more cameras are configured to capture surrounding views from the detachable body. One of the three or more cameras faces a driver seat of the vehicle in response to the detachable body being coupled to the windshield of the vehicle. The video may be processed by the system, the cloud, or a combination of them.

Abstract: Systems and methods are provided for distributed video storage and search with edge computing. The method may comprise caching a first portion of data on a first device. The method may further comprise determining, at a second device, whether the first device has the first portion of data. The determining may be based on whether the first piece of data satisfies a specified criterion. The method may further comprise sending the data, or a portion of the data, and/or a representation of the data from the first device to a third device.

Abstract: The present disclosure provides devices, systems and methods for mapping of traffic boundaries.

Abstract: Systems and methods are provided for distributed video storage and search with edge computing. The method may comprise caching a first portion of data on a first device. The method may further comprise determining, at a second device, whether the first device has the first portion of data. The determining may be based on whether the first piece of data satisfies a specified criterion. The method may further comprise sending the data, or a portion of the data, and/or a representation of the data from the first device to a third device.

Abstract: A technique for finding and estimating the locations of atmospheric thermals for the purpose of exploiting the updraft energy to enable the aircraft to remain aloft while reducing or eliminating the need to expend fuel or energy and operational regardless of whether the aircraft is under powered flight or is gliding.