Patents by Inventor David A. Karlin

David A. Karlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF PICOPLATIN TO TREAT COLORECTAL CANCER
    Publication number: 20120156199
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
    Type: Application
    Filed: May 12, 2010
    Publication date: June 21, 2012
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • USE OF PICOPLATIN TO TREAT PROSTATE CANCER
    Publication number: 20120122825
    Abstract: The invention provides a method of treatment of metastatic hormone-refractory prostate cancer involving substantially as concurrent administration of picoplatin and docetaxel. Prednisone may also be administered. Dosages and dosing regimens are provided.
    Type: Application
    Filed: May 12, 2010
    Publication date: May 17, 2012
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin MD, Hazel B. Breitz MD, Paul L. Weiden MD, Robert De Jager
  • Use of picoplatin to treat colorectal cancer
    Patent number: 8178564
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. Dosages, dosing schedules, and ancillary treatments are described.
    Type: Grant
    Filed: February 6, 2009
    Date of Patent: May 15, 2012
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • Use of picoplatin to treat colorectal cancer
    Patent number: 8173686
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
    Type: Grant
    Filed: May 13, 2009
    Date of Patent: May 8, 2012
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • Use of picoplatin to treat colorectal cancer
    Patent number: 8168661
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
    Type: Grant
    Filed: May 12, 2009
    Date of Patent: May 1, 2012
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • Use of picoplatin to treat colorectal cancer
    Patent number: 8168662
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. Dosages, dosing schedules, and ancillary treatments are described.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: May 1, 2012
    Assignee: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • USE OF PICOPLATIN AND BEVACIZUMAB TO TREAT COLORECTAL CANCER
    Publication number: 20110052580
    Abstract: The invention provides a method of treatment of metastatic colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with bevacizumab (Avastin®) and optionally, with 5-FU and leucovorin in a variety of treatment regimens. The invention also provides a use of picoplatin in conjunction with bevacizumab and, optionally, 5-FU and leucovorin, for the treatment of metastatic colorectal cancer.
    Type: Application
    Filed: February 6, 2009
    Publication date: March 3, 2011
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: Ronald A. Martell, David A. Karlin
  • PICOPLATIN AND AMRUBICIN TO TREAT LUNG CANCER
    Publication number: 20110053879
    Abstract: A method for treatment of lung cancer comprising administration of picoplatin and amrubicin, or comprising radiation therapy and picoplatin is provided. A use of picoplatin in conjunction with amrubicin for treatment of lung cancer is provided. The lung cancer can be SCLC or NSCLC. The cancer can be resistant or refractory to treatment or that progresses following cessation of first-line organoplatinum chemotherapy. The treatment can include the administration of picoplatin and amrubicin, optionally in conjunction with a regimen of best supportive care. Multiple doses of the drug or drug combination can be administered.
    Type: Application
    Filed: February 6, 2009
    Publication date: March 3, 2011
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: Ronald A. Martell, David A. Karlin
  • USE OF PICOPLATIN AND CETUXIMAB TO TREAT COLORECTAL CANCER
    Publication number: 20110052581
    Abstract: The invention provides a method of treatment of metastatic colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with cetuximab, 5-FU, and leucovorin in a variety of treatment regimens. The invention also provides a use of picoplatin in conjunction with cetuximab, 5-FU, and leucovorin for treatment of metastatic colorectal cancer. The invention further provides kits adapted for administration of picoplatin in conjunction with cetuximab. Also, methods for determining dosage regimens for patients afflicted with a cancer comprising EGFR are provided.
    Type: Application
    Filed: February 6, 2009
    Publication date: March 3, 2011
    Applicant: Poniard Pharmaceuticals Inc.
    Inventors: David A. Karlin, Ronald A. Martell
  • STABILIZED PICOPLATIN DOSAGE FORM
    Publication number: 20100215727
    Abstract: Methods for stabilizing aqueous solutions of picoplatin are provided. Such stable, preferably aseptic solutions are particularly useful for preparing unit dosages of picoplatin for oral or intravenous administration, preferably in combination with at least one additional non-platinum anti-cancer agent.
    Type: Application
    Filed: December 10, 2009
    Publication date: August 26, 2010
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: Alistair J. Leigh, Ronald A. Martell, David A. Karlin, Cheni Kwok, Christopher A. Procyshyn, Hazel B. Breitz, Paul L. Weiden
  • COMBINATION THERAPY FOR OVARIAN CANCER
    Publication number: 20100178328
    Abstract: The present invention provides a method to treat ovarian cancer by the administration of effective amounts of picoplatin and pegylated liposomal doxorubicin.
    Type: Application
    Filed: December 10, 2009
    Publication date: July 15, 2010
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: Ronald A. Martell, David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • USE OF PICOPLATIN TO TREAT COLORECTAL CANCER
    Publication number: 20090306034
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
    Type: Application
    Filed: May 13, 2009
    Publication date: December 10, 2009
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • USE OF PICOPLATIN TO TREAT COLORECTAL CANCER
    Publication number: 20090275549
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens.
    Type: Application
    Filed: May 12, 2009
    Publication date: November 5, 2009
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden
  • USE OF PICOPLATIN TO TREAT COLORECTAL CANCER
    Publication number: 20090197854
    Abstract: The invention provides a method of treatment of colorectal cancer by administration of the anti-cancer platinum drug picoplatin in conjunction with 5-FU and leucovorin in a variety of treatment regimens. Dosages, dosing schedules, and ancillary treatments are described.
    Type: Application
    Filed: February 6, 2009
    Publication date: August 6, 2009
    Applicant: Poniard Pharmaceuticals, Inc.
    Inventors: David A. Karlin, Hazel B. Breitz, Paul L. Weiden