Abstract: The present invention relates to a new class of non-fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.

Abstract: Systems, methods, and apparatus for conditioning bamboo or other types of vegetable cane are provided. In one aspect, the present technology provides a cane processing assembly for use with a substantially flattened sheet of bamboo culm or vegetable cane having a plurality of longitudinally oriented fiber bundles. The assembly comprises first and second conditioning rollers configured to apply pressure to the sheet that breaks at least some natural bonds connecting laterally adjacent fiber bundles in the sheet. The first and second conditioning rollers are adjustable relative to each other so as to vary the pressure applied to the sheet by the first and second conditioning rollers.

Abstract: Disclosed are dairy products fortified with dairy minerals and methods of making the dairy products. The fortified dairy products exhibit enhanced fresh dairy flavor notes. In one aspect, the fortified dairy product is a concentrated dairy liquid.

Abstract: The present invention relates to a new class of non-fused thiophene derivatives and their uses for treating diseases such as infection, cancer, metabolic diseases, cardiovascular diseases, iron storage disorders and inflammatory disorders.

Abstract: Disclosed are dairy products fortified with dairy minerals and methods of making the dairy products. The fortified dairy products exhibit enhanced fresh dairy flavor notes. In one aspect, the fortified dairy product is a concentrated dairy liquid. In another aspect, the fortified dairy product is a cheese product, such as cream cheese, processed cheese, or cultured cheese.

Abstract: In one embodiment, a method for generating a message to a friend of a user is provided, comprising: processing activity data of a first user measured by an activity monitoring device to update a value of an activity metric for the first user; identifying a change in an inequality relationship between the value of the activity metric for the first user and a value of the activity metric for a second user; in response to identifying the change in the inequality relationship, prompting the first user to generate a message to the second user.

Abstract: In one embodiment, a method for generating a message to a friend of a user is provided, comprising: processing activity data of a first user measured by an activity monitoring device to update a value of an activity metric for the first user; identifying a change in an inequality relationship between the value of the activity metric for the first user and a value of the activity metric for a second user; in response to identifying the change in the inequality relationship, prompting the first user to generate a message to the second user.

Abstract: The present technology relates generally to a platform and concrete composite slab system used as a building material. A platform, is formed from joined, substantially coplanar boards with connector plates partially embedded between the boards such that a portion of the connector plates extend above the platform's top surface. A reinforcing material (e.g., wire mesh and/or rebar) can be arranged on the prongs or other portion of the connector plates spaced above the platform and concrete is poured over the reinforcing material and allowed to cure, forming a reinforced concrete layer that encases the connector plates and reinforcing material. The connector plates act as standoffs and help to suspend the reinforcing material in the middle of the concrete layer to increase the strength of the reinforced concrete and to fixedly anchor and bind the concrete layer to the platform, so as to establish a composite action between the platform and the concrete.

Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

Abstract: The present technology relates generally to a platform and concrete composite slab system used as a building material. A platform, is formed from joined, substantially coplanar boards with connector plates partially embedded between the boards such that a portion of the connector plates extend above the platform's top surface. A reinforcing material (e.g., wire mesh and/or rebar) can be arranged on the prongs or other portion of the connector plates spaced above the platform and concrete is poured over the reinforcing material and allowed to cure, forming a reinforced concrete layer that encases the connector plates and reinforcing material. The connector plates act as standoffs and help to suspend the reinforcing material in the middle of the concrete layer to increase the strength of the reinforced concrete and to fixedly anchor and bind the concrete layer to the platform, so as to establish a composite action between the platform and the concrete.

Abstract: Methods and systems for malicious message detection and processing are provided. An example method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource or a known malicious resource. The intermediary node may have a processor and a memory for storing executable instructions to perform the method. The example method further includes hashing a unique identifier for each recipient of the message; coupling each of the hashed unique identifiers with the link to create an unique updated link for each recipient; and for each recipient, replacing the link in the message with their corresponding unique updated link. The method may include causing forwarding of the updated message with the corresponding unique updated link to each recipient. If the resource is a malicious resource, the unique update link may be to a block webpage associated with a trusted resource.

Abstract: A downhole valve assembly comprises a sleeve concentric with a housing and movable relative to a port through the housing to control flow of fluid through the port. A sensor assembly provides indicates the relative positions of the sleeve and housing, and comprises first and second sensors on e.g. the housing which detect markers on e.g. the sleeve. The sensor outputs are produced by processing (e.g. combining, integrating, summing, subtracting or otherwise processing) the signal components of each of the first and second sensors to correct for misalignment of the sleeve with the housing. The sensor output provides position information for more than one plane, and the output signal therefore allows for correction of errors in the position information arising from misalignment of the sleeve with the housing.

Abstract: Methods and corresponding systems for malicious message detection and processing are provided herein. According to example embodiments, a method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource. The intermediary node may have a processor and a memory for storing executable instructions to perform the method. The example method further includes hashing a unique identifier for a recipient of the message; coupling the hashed identifier with the link to create an updated link, and replacing the link in the message with the updated link. The method may include causing forwarding of the updated message to a recipient. Clicking on or otherwise selecting the updated link by the one or more recipients of the message may be tracked. The method may include mapping the hashed identifier to the unique identifier of each of the one or more recipients.

Abstract: This invention relates to novel substituted benzamide according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

Abstract: A method includes receiving, at a control node of a cloud computing network, a first enterprise policy specific to the first enterprise and a second enterprise policy specific to the second enterprise, and managing communications between at least one user device of the first enterprise and the at least one enterprise application hosted on behalf of the first enterprise based on the first enterprise policy. The method also includes managing communications between at least one user device of the second enterprise and the at least one enterprise application hosted on behalf of the second enterprise based on the second enterprise policy.

Abstract: Methods and corresponding systems for malicious message detection and processing are provided herein. According to example embodiments, a method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource. The intermediary node may have a processor and a memory for storing executable instructions to perform the method. The example method further includes hashing a unique identifier for a recipient of the message; coupling the hashed identifier with the link to create an updated link, and replacing the link in the message with the updated link. The method may include causing forwarding of the updated message to a recipient. Clicking on or otherwise selecting the updated link by the one or more recipients of the message may be tracked. The method may include mapping the hashed identifier to the unique identifier of each of the one or more recipients.

Abstract: The present technology relates generally to a platform and concrete composite slab system used as a building material. A platform, is formed from joined, substantially coplanar boards with connector plates partially embedded between the boards such that a portion of the connector plates extend above the platform's top surface. A reinforcing material (e.g., wire mesh and/or rebar) can be arranged on the prongs or other portion of the connector plates spaced above the platform and concrete is poured over the reinforcing material and allowed to cure, forming a reinforced concrete layer that encases the connector plates and reinforcing material. The connector plates act as standoffs and help to suspend the reinforcing material in the middle of the concrete layer to increase the strength of the reinforced concrete and to fixedly anchor and bind the concrete layer to the platform, so as to establish a composite action between the platform and the concrete.

Abstract: In one embodiment, a method for generating a message to a friend of a user is provided, comprising: processing activity data of a first user measured by an activity monitoring device to update a value of an activity metric for the first user; identifying a change in an inequality relationship between the value of the activity metric for the first user and a value of the activity metric for a second user; in response to identifying the change in the inequality relationship, prompting the first user to generate a message to the second user.

Abstract: Systems and methods for malicious message detection and processing are provided herein. According to various embodiments, a method includes detecting, via an intermediary node, a link included in a message, the link being associated with an unknown resource, hashing a unique identifier for a recipient of the message, coupling the hashed identifier with the link, creating an updated link, and forwarding an updated message, including the updated link, to the recipient.

Abstract: One embodiment provides a cane processing assembly for use with a substantially cylindrical bamboo culm having a longitudinal axis and a plurality of nodes. The assembly comprising a feeder, a perforating station adjacent to the feeder to receive the culm, the perforating station having an annular cutter assembly with cutting blades positioned around an open central area that receives the culm. The cutting blades are radially movable between retracted and extended positions, wherein the cutting blades are positioned to cut into a node around the circumference of the culm. A splitter station receives the culm after the perforating station. The splitter station has a splitting blade configured to cut the culm along its length. A planar station adjacent to the splitter station has a plurality of rollers positioned to engage and flatten the cut culm into a planar configuration.