Patents by Inventor David A. Kwajewski

David A. Kwajewski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus and method for the assessment of concentration profiling and permeability rates
    Patent number: 10228358
    Abstract: An apparatus for the combined assessment of dissolution and permeability relies on a receiver chamber that is contained within a donor chamber. A membrane is provided between the two chambers. Measurements can be taken to determine solute amounts of a drug introduced in the donor chamber and amounts of permeated solute in the receiver chamber. Also described are techniques for the assessment of a dissolution rate and total amount of dissolved compound, together with their effect on absorption potential of a compound or a compound product as well as approaches for evaluating in vivo relevant differences between formulations of a compound through their effect on the absorption potential of the compound.
    Type: Grant
    Filed: April 14, 2016
    Date of Patent: March 12, 2019
    Assignee: PION INC.
    Inventors: Ajit S. Narang, Dan Tang, Scott P. Jennings, Neil Mathias, Konstantin L. Tsinman, Deren J. Dohoda, David A. Kwajewski, Michael G. Kelly
  • Apparatus and Method for the Assessment of Concentration Profiling and Permeability Rates
    Publication number: 20160305922
    Abstract: An apparatus for the combined assessment of dissolution and permeability relies on a receiver chamber that is contained within a donor chamber. A membrane is provided between the two chambers. Measurements can be taken to determine solute amounts of a drug introduced in the donor chamber and amounts of permeated solute in the receiver chamber. Also described are techniques for the assessment of a dissolution rate and total amount of dissolved compound, together with their effect on absorption potential of a compound or a compound product as well as approaches for evaluating in vivo relevant differences between formulations of a compound through their effect on the absorption potential of the compound.
    Type: Application
    Filed: April 14, 2016
    Publication date: October 20, 2016
    Inventors: Ajit S. Narang, Dan Tang, Scott P. Jennings, Neil Mathias, Konstantin L. Tsinman, Deren J. Dohoda, David A. Kwajewski, Michael G. Kelly