Abstract: A pro-apoptotic solid dispersion comprises, in essentially non-crystalline form, a Bcl-2 family protein inhibitory compound of Formula I as defined herein, dispersed in a solid matrix that comprises (a) a pharmaceutically acceptable water-soluble polymeric carrier and (b) a pharmaceutically acceptable surfactant. A process for preparing such a solid dispersion comprises dissolving the compound, the polymeric carrier and the surfactant in a suitable solvent, and removing the solvent to provide a solid matrix comprising the polymeric carrier and the surfactant and having the compound dispersed in essentially non-crystalline form therein. The solid dispersion is suitable for oral administration to a subject in need thereof for treatment of a disease characterized by overexpression of one or more anti-apoptotic Bcl-2 family proteins, for example cancer.

Abstract: Disclosed is a dynamic detector to detect an environmental condition including a power-supply level relative to a predetermined threshold signal during a training phase; and an adjustable buffer, coupled with the dynamic detector, configured to adjust output drive strength during the training phase in response to the detected environmental condition.

Abstract: The system contains a plurality of laser projectors. An image of a marking is projected in a synchronized form by the plurality of laser projectors. A computer network provides communication with the laser projectors. A central workstation communicates with the laser projectors through the computer network. The central workstation coordinates the image projected by the laser projectors.

Abstract: The system contains a plurality of laser projectors. An image of a marking is projected in a synchronized form by the plurality of laser projectors. A computer network provides communication with the laser projectors. A central workstation communicates with the laser projectors through the computer network. The central workstation coordinates the image projected by the laser projectors.

Abstract: The present invention concerns data transition method and apparatus for driving a set of write data signals to an inactive (or deasserted) state upon completion of a WRITE to a particular group of memory cells. The present invention drives the write data signals to a an inactive state to end a WRITE without waiting for the end of the write control pulse. The present invention triggers a group of data write buffers to drive one of the write data signals to a "0" at the beginning of the WRITE control pulse or at a data input transition during a WRITE. A delayed transition of the write data signals may be used to drive both the write data signals to a "1"? to end the WRITE within a particular memory group. The write data transition detection is accomplished at the write data inputs of the groups of memory cells without relying on global chip data input pin transition detection and pulse width setting.