Abstract: The present disclosure relates to methods of preventing and/or treating Ulcerative colitis (UC) comprising administering an ?4?7 small molecule inhibitor alone and in combination with an anti-IL-12/IL-23 inhibitor.

Abstract: In a dispenser, spout heating structure is provided for maintaining the product in the spout in a flowable and uncongealed state. The heating structure includes a base which supports a heat conductive elongate block, the block having opposite side surfaces and a top surface that engages the underside of the spout in heat transfer relationship therewith. Heat from the elongate block is directly transferred to the spout, and a heat conductive sheath engages the upper portion of the spout and the side surfaces of the block to enhance heating of the spout to thereby maintain the product in a flowable condition.

Abstract: A tote box carrier includes cooperating pairs of spaced apart side rails which function to guide and support tote boxes associated with the carrier. Clip stop elements connected to the side rails function to prevent inadvertent removal of the tote boxes from the carrier. The clip stop elements also have an inoperative position which enables the tote boxes to be removed from the carrier.