Abstract: A hybrid edge and cloud system for detecting and identifying bird vocalizations including an edge device having an edge neural network. The edge neural network is trained with audio samples for making predictions about identification of the bird vocalizations. The system includes an audio sensor connected to the edge neural network for sending sound information to the edge neural network. The system includes a cloud computing system having a cloud neural network for processing the sound information, a first storage service, a second storage service, and a hit table which stores metadata about sound detections. The edge neural network generates a score for each of the trained audio samples based on predictions made from a sound audio clip and selects a top scoring audio sample. The hybrid edge and cloud system includes a browsing device having access to the cloud computing system and may request information from the hit table.

Abstract: Provided are deglycosylation methods designed to optimize the yield of a Veratrum alkaloid from Veratrum plant material and/or from an extract of Veratrum plant material.

Abstract: Provided herein are methods of producing three-dimensional (3-D) microtissue from a starting cell suspension of pluripotent stem cell (PSC)-derived hepatocytes. Such a method may comprise supplementing the cell suspension with cell adhesion-promoting components and culturing the PSC-derived hepatocytes on a non-adhesive surface to produce the microtissue.

Abstract: Provided are deglycosylation methods designed to optimize the yield of a Veratrum alkaloid from Veratrum plant material and/or from an extract of Veratrum plant material.

Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

Abstract: Provided are deglycosylation methods designed to optimize the yield of Veratrum alkaloid from Veratrum plant material and/or from an extract of Veratrum plant material.

Abstract: An electrostatic speaker is constructed using a thin flexible membrane as the active member. This membrane is uniformly positioned against at least one printed circuit board containing at least one stator fixed in the PCB. Variations in structure are provided, all including at least one PCB and a membrane. In a preferred embodiment, intermeshing opposing ridges on the PCBs are adjacent to a central vibrating area of the membrane, and serve to position and tension the membrane. Attachment means connect the PCBs together, and electrical connections permit the passage of current to bias the membrane and to drive the stators to vibrate the membrane, producing acoustical output in the sonic or ultrasonic ranges. The invention also relates to the electrostatic speakers produced by this method of manufacture.

Abstract: The invention is directed to an orthopaedic apparatus 24, 80, 380, 480, 580 for positioning an implant 22, 322, 422 relative to an end of a bone. The implant has at least one extractor opening 30, 330, 430 and a shoulder 26, 326, 426 with a slot therein. The positioning apparatus includes a shaft 32, 82, 382, 482 having a fixed impactor tip at an end thereof. The impactor tip is configured to be received within the implant slot. At least one clamping jaw is connected to the shaft, and includes a projection which is configured to be received in the at least one extractor opening. The at least one clamping jaw is preferably detachably connected to the shaft.

Abstract: The invention is directed to an alignment device for aligning a prosthetic hip stem implant with an opening formed in a proximal femur. The hip stem implant includes a landmark and the proximal femur includes a visual alignment mark. The alignment device includes an implant engaging portion configured for attachment with the landmark on the hip stem implant. The alignment device also includes a needle indicator connected with the implant engaging portion and having an end which may be positioned relative to the visual alignment mark on the proximal femur, thereby aligning the prosthetic hip stem implant relative to the opening in the proximal femur.

Abstract: Nucleic acid isolates capable of hybridizing only to the Y-chromosome specific DNA sequences of cattle, sheep and goats are described, as are methods for the determination of the sex chromosome constitution of a tissue or cell sample.