Abstract: Indazole compounds for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of an indazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: An open-cavity, reduced-pressure treatment device and system for treating a cavity in a patient's body, such as an abdominal cavity, is presented. In one instance, an open-cavity, reduced-pressure treatment device includes a plurality of encapsulated leg members, each having an interior portion with a leg manifold member and formed with fenestrations operable to allow fluid flow into the interior portion, and a central connection member fluidly coupled to the plurality of encapsulated leg members. The central connection member has a connection manifold member. The open-cavity, reduced-pressure treatment devices, systems, and methods allow for, among other things, removal of fluids.

Abstract: Some embodiments include an assembly which has channel material pillars, and which has memory cells along the channel material pillars. A conductive structure is under the channel material pillars. The conductive structure has doped semiconductor material in direct contact with bottom regions of the channel material pillars. One or more of magnesium, scandium, yttrium and lanthanide elements is along the bottom regions of the channel material pillars. Some embodiments include methods of forming assemblies. A structure is formed, and a mass is formed against an upper surface of the structure. Plugs are formed within openings in the mass. The plugs comprise a second material over a first material. The first material includes one or more of magnesium, scandium, yttrium and lanthanide elements. Openings are formed to terminate on the first material, and are then extended through the first material. Channel material pillars are formed within the openings.

Abstract: A method for providing purchase suggestions to a customer is provided. The method may include a computer server associated with a store receiving multiple receipts for past purchase transactions from a customer. The server may identify products on the receipts and analyze the products and receipt dates to determine a frequency with which the customer purchases a particular product. The server may also determine a date when the customer last purchased the particular product and transmit a purchase suggestion for the product to the customer at a time correlated with the customer needing to purchase the particular product based on a date when the customer last purchased the particular product and the frequency with which the customer purchases the particular product.

Abstract: Provided herein are compounds according to Formulas (I) or (II) and pharmaceutically acceptable salts thereof, and compositions comprising the same, for use in various methods, including treating cancer, abnormal cellular proliferation, angiogenesis, Alzheimer's disease, lung disease, osteoarthritis, idiopathic pulmonary fibrosis and neurological conditions/disorders/diseases.

Abstract: Methods for producing dissolving grade pulp and microcrystalline cellulose from tobacco are provided. The methods include chemical pulping a tobacco input to form a tobacco pulp. Chemical pulping the tobacco input includes combining the tobacco input with a strong base defining a weight from about 5% to about 50% of the tobacco input, and heating the tobacco input and the strong base with an H-factor from about 500 to about 3,300. Further, the methods include bleaching the tobacco pulp to produce a dissolving grade pulp. Bleaching the tobacco pulp may include chlorination of the tobacco pulp with a chlorine dioxide solution, and caustic extraction of the tobacco pulp with a second strong base. A related tobacco-derived microcrystalline cellulose product is also provided, which can be used as a binder, a filler, and/or a texturizer in a tobacco product, such as a smokeless tobacco product.

Abstract: In an access device associated with a first network cell, a method for enabling user equipment (UE) to obtain a service unavailable through the first network cell includes receiving a request for the UE to access the service, and identifying, in a message to the UE, a plurality of second network cells providing the service.

Abstract: Some embodiments include an assembly which has channel material pillars, and which has memory cells along the channel material pillars. A conductive structure is under the channel material pillars. The conductive structure has doped semiconductor material in direct contact with bottom regions of the channel material pillars. One or more of magnesium, scandium, yttrium and lanthanide elements is along the bottom regions of the channel material pillars. Some embodiments include methods of forming assemblies. A structure is formed, and a mass is formed against an upper surface of the structure. Plugs are formed within openings in the mass. The plugs comprise a second material over a first material. The first material includes one or more of magnesium, scandium, yttrium and lanthanide elements. Openings are formed to terminate on the first material, and are then extended through the first material. Channel material pillars are formed within the openings.

Abstract: The present disclosure relates to 4-Azaindazole compounds having the following structure: or a pharmaceutically acceptable salt thereof, for treating various diseases and pathologies are disclosed. More particularly, the present disclosure concerns the use of a 4-azaindazole compound or analogs thereof, in the treatment of disorders characterized by the activation of Wnt pathway signaling (e.g., cancer, abnormal cellular proliferation, angiogenesis, fibrotic disorders, bone or cartilage diseases, and osteoarthritis), the modulation of cellular events mediated by Wnt pathway signaling, as well as genetic diseases and neurological conditions/disorders/diseases due to mutations or dysregulation of the Wnt pathway and/or of one or more of Wnt signaling components. Also provided are methods for treating Wnt-related disease states.

Abstract: A pin of a hinge system movable between a first position and a second position is provided, wherein in the first position, the pin is received within a first component and a second component. The pin includes a cylindrical body coupled to an actuator for movement along an axis between the first position and the second position. A tip is removably attached to an end of the cylindrical body. The tip is configured to contact at least one of the first component and the second component when the pin is in the first position.

Abstract: Tri-layer semiconductor stacks for patterning features on solar cells, and the resulting solar cells, are described herein. In an example, a solar cell includes a substrate. A semiconductor structure is disposed above the substrate. The semiconductor structure includes a P-type semiconductor layer disposed directly on a first semiconductor layer. A third semiconductor layer is disposed directly on the P-type semiconductor layer. An outermost edge of the third semiconductor layer is laterally recessed from an outermost edge of the first semiconductor layer by a width. An outermost edge of the P-type semiconductor layer is sloped from the outermost edge of the third semiconductor layer to the outermost edge of the third semiconductor layer. A conductive contact structure is electrically connected to the semiconductor structure.

Abstract: A laminar flow diffuser with integrated lighting has a frame for supporting an air plenum and a lower housing. The air plenum receives conditioned air from a source of conditioned. The lower housing is attached to the bottom of the plenum. An aperture plate damper installed below the top plenum regulates the flow of air from the plenum through the laminar flow diffuser. A clear or translucent engineered, fire rated polymer perforated diffuser face forms the outlet from the lower housing to the room below. LED strips are positioned around the inside periphery of the lower housing. A light guide is installed adjacent the LED lighting strips to spread the light across the area of the perforated diffuser face.

Abstract: A system for use in performing ocular examinations, such as convergence and accommodation useful in diagnosing traumatic brain injury (including concussion), includes an assessment device. The assessment device includes a portable carrier having a visual target and a distance measurement component. The system may further include a communications channel and a companion device. The distance measurement component communicates via the communication channel with the companion device. The companion device stores one or more distances measured by the distance measurement component.

Abstract: A system is provided with memory and a processor. The memory is configured to store data representative of a multi-valued decision diagram (MDD). The processor is in communication with the memory and is programmed to receive a current selection of one or more of the features, and to determine a feature state for each of the one or more features, based on the current selection and the possible configurations defined by the MDD. The processor is further programmed to calculate an availability bitset indicative of which features as available for further selection, consistent with the valid configurations and without violating existing constraints of the current selection.

Abstract: An optical fiber ribbon and a related cable are provided. The ribbon includes a first group of at least one optical fiber and a second group of at least two optical fibers coupled together. The ribbon includes a first hinge coupling the first group to the second group. The hinge allows movement of the first group and the second group of optical fibers relative to each other such that the ribbon is moveable between an aligned position and a collapsed position. The number of optical fibers in the first group is less than the number of optical fibers in second group.

Abstract: The present application discloses a compound which is which activates Wnt/?-catenin signaling and thus treats or prevents diseases related to signal transduction, such as osteoporosis and osteoarthropathy; osteogenesis imperfecta, bone defects, bone fractures, periodontal disease, otosclerosis, wound healing, craniofacial defects, oncolytic bone disease, traumatic brain injuries related to the differentiation and development of the central nervous system, comprising Parkinson's disease, strokes, ischemic cerebral disease, epilepsy, Alzheimer's disease, depression, bipolar disorder, schizophrenia; eye diseases such as age related macular degeneration, diabetic macular edema or retinitis pigmentosa and diseases related to differentiation and growth of stem cell, comprising hair loss, hematopoiesis related diseases and tissue regeneration related diseases.

Abstract: A dynamic power control circuit is provided. The control circuit can detect the presence of the external power source as well as detect one or more conditions of the device. For instance, the control circuit can detect a voltage difference between a first node coupling a first power output and a system circuit and a second node coupling a second power output and the batteries. The control circuit can also detect the activation or deactivation of the external power source. Based on the inputs, the control circuit can cause the controlled resistor to dynamically adjust a level of impedance between the first node and the second node. The controlled impedance between the first node and the second node enables the system circuit to dynamically utilize power supplied by the external power source as well as power supplied by the batteries.

Abstract: A system is provided with a memory device and a processor. The memory device is adapted to store data representative of a multi-valued decision diagram (MDD) specifying a buildable space of all possible configurations of a vehicle. The processor is in communication with the memory and is programmed to identify an invalid configuration, and to generate a restricted buildable space, including to determine an edit distance of each complete path indicative of a number of features to change the invalid configuration of that path to one of the valid configurations, identify a minimum of the edit distances, and remove configurations having edit distances larger than the minimum. The processor is further programmed to identify at least one feature to change the invalid configuration to at least one valid configuration based on the restricted buildable space; and to generate output indicative of the at least one feature to change.

Abstract: A system and method for measuring the complex resistivity of a ground section. One embodiment utilizes stand-off capacity-coupled resistivity (CCR) sensing to inject current into the ground at a frequency within the range of 1 Khz to 1 MHz. A sensor detects the voltage which is used to determine the complex resistively of the ground and, thus, ground content. The system and method permits surveys to be conducted at speeds of 10-20 mph or more. Alternatively, current is injected into the ground along a plasma channel that is enabled with a high energy laser. Alternatively, an alpha particle generator may be used to inject the current. Multiple frequencies may be used within the range of 1 KHz to 1 MHz to produce an impedivity spectroscopy to thereby determine and/or display a map of ground content.