Patents by Inventor David A. McGuire

David A. McGuire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11963996
    Abstract: Knee pain caused by osteoarthritis is relieved by modifying the shape change of bone(s) underlying articular cartilage, by a method comprising evaluating the bone shape of the patient's joint, injecting the patient with a peptide of SEQ ID No. 1 or applying other therapeutic interventions that can reduce the shape change of the bone(s) underlying articular cartilage, and thereafter evaluating the bone shape of the patient's joint.
    Type: Grant
    Filed: September 27, 2019
    Date of Patent: April 23, 2024
    Assignee: ORTHOTROPHIX, Inc.
    Inventors: Yoshinari Kumagai, Dawn McGuire, Meghan Miller, David Rosen
  • Publication number: 20240084622
    Abstract: A latch for use in a motor vehicle. The latch including a first housing member, a second housing member, and a clip. The first housing member including a first edge member, the second housing member including a second edge member. The clip including a first leg and a second leg collectively configured to sandwich the first and second edge members to fix the first housing member to the second housing member.
    Type: Application
    Filed: September 13, 2022
    Publication date: March 14, 2024
    Applicant: Brose Schließsysteme GmbH & Co. Kommanditgesellschaft
    Inventors: David ROSALES, Deon McGUIRE, Andrii LEVAKOV
  • Patent number: 11922567
    Abstract: The present invention facilitates efficient and effective image processing. A network can comprise: a first system configured to perform a first portion of lighting calculations for an image and combing results of the first portion of lighting calculations for the image with results of a second portion of lighting calculations; and a second system configured to perform the second portion of lighting calculations and forward the results of the second portion of the lighting calculations to the first system. The first and second portion of lighting calculations can be associated with indirect lighting calculations and direct lighting calculations respectively. The first system can be a client in a local location and the second system can be a server in a remote location (e.g., a cloud computing environment). The first system and second system can be in a cloud and a video is transmitted to a local system.
    Type: Grant
    Filed: April 4, 2022
    Date of Patent: March 5, 2024
    Assignee: NVIDIA Corporation
    Inventors: Morgan McGuire, Cyril Crassin, David Luebke, Michael Mara, Brent Oster, Peter Shirley, Peter-Pike Sloan, Christopher Wyman
  • Publication number: 20230242972
    Abstract: The present invention provides an improved capacitive bead sensor for detection and/or quantification of target analytes in a sample, with a detection limit down to single-beads, which is re-usable for multiple bead tests, or for a continuous flow of beads, and which is easily manufacturable and automatable. It enables sensitivity down to single molecule detection without the need for enzymatic amplification such as PCR, by use of various structural advantages and electronic signal amplification techniques that further allow for multiplex target detection not only across various nucleic acid targets but across entire target classes allowing for simultaneous detection of viral nucleic acids and host antibodies to that virus for example.
    Type: Application
    Filed: January 27, 2023
    Publication date: August 3, 2023
    Inventors: Tara Dalton, Timothy Cummins, Margaret Aherne, David McGuire, John O'Driscoll, Colin King, Paul Free, Brian O'Farrell
  • Patent number: 10513729
    Abstract: Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.
    Type: Grant
    Filed: February 26, 2016
    Date of Patent: December 24, 2019
    Assignee: STOKES BIO LIMITED
    Inventors: Mauro Aguanno, Brian T. Chawke, Kieran Curran, Tara Dalton, Mark Davies, Xiaona Hou, David Kinahan, Mark Korenke, David McGuire, Michael Sayers, Noel Sirr, Ryan J. Talbot, Brian Barrett, Damian Curtin, Damien King, Conor McCarthy
  • Publication number: 20190204795
    Abstract: A system selectively activates and deactivates delivery of power to a device by a power outlet using a pulsed sequence of on commands delivered at randomized intervals. The on commands may be sent by any number of sending devices. So long as a receiving device continues to receive on signals from any sending device on a selected channel, the receiving device will remain switched on and deliver power from the power outlet to a connected load. If the receiving device either (a) receives an off signal on the selected channel, or (b) stops receiving on signals on the selected channel for a timeout period, the receiving device will switch off and stop delivering power to the connected load.
    Type: Application
    Filed: December 29, 2017
    Publication date: July 4, 2019
    Inventors: Michael R. Neilson, David McGuire
  • Patent number: 10266878
    Abstract: Aspects of the present disclosure include a complete genomic analysis device and methods of use thereof for high throughput genomic analysis of biological samples.
    Type: Grant
    Filed: August 3, 2015
    Date of Patent: April 23, 2019
    Assignee: GENCELL BIOSYSTEMS LTD.
    Inventors: Mark Dalton, John Daly, Mark McCabe, Padraig Walsh, Kevin Daulnay, David McGuire, Maria Kerin, Maria O'Connor, Colin King, Keith Mooney
  • Patent number: 10252261
    Abstract: Devices, systems and methods for making and handling liquid samples are disclosed.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 9, 2019
    Assignee: GENCELL BIOSYSTEMS LTD.
    Inventors: Kieran Curran, David McGuire, Brian Chawke, Paul Fleming, Brian Barrett, Noel Sirr
  • Patent number: 10081808
    Abstract: Methods, devices and systems for handling sample liquids, encapsulating liquids and magnetic particles are disclosed.
    Type: Grant
    Filed: August 2, 2017
    Date of Patent: September 25, 2018
    Assignee: GENCELL BIOSYSTEMS LTD
    Inventors: Kieran Curran, David McGuire
  • Patent number: 10077094
    Abstract: A system for a mooring device is herein disclosed. The mooring device comprises a disc and a collar. The disc comprises a central orifice and one or more holes. The central orifice is mountable to a boat seat post. The holes large enough to accommodate a mooring line to pass through. The collar positionable on an end of the disc. A method for mooring a boat is further disclosed. Specifically, the method comprises mounting a mooring device onto a boat seat post. The mooring device comprises a disc and a collar. The disc comprises a central orifice and one or more holes. The central orifice is mountable to the boat seat post. The holes attachable to a mooring line. Further, the method comprises fastening the collar onto the boat seat post.
    Type: Grant
    Filed: June 2, 2014
    Date of Patent: September 18, 2018
    Inventors: Anna Marie McGuire, James David McGuire
  • Publication number: 20180111118
    Abstract: Devices, systems and methods for making and handling liquid samples are disclosed.
    Type: Application
    Filed: June 28, 2017
    Publication date: April 26, 2018
    Inventors: Kieran Curran, David McGuire, Brian Chawke, Paul Fleming, Brian Barrett, Noel Sirr
  • Publication number: 20180016573
    Abstract: Methods, devices and systems for handling sample liquids, encapsulating liquids and magnetic particles are disclosed.
    Type: Application
    Filed: August 2, 2017
    Publication date: January 18, 2018
    Inventors: Kieran Curran, David McGuire
  • Patent number: 9789484
    Abstract: Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic systems. The charging is performed by producing an ion field between an ionizing electrode and an opposed ground electrode. A fluid-containing vessel is positioned between the opposed electrodes and the ion field charges the fluid in the vessel.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: October 17, 2017
    Assignee: Stokes Bio Limited
    Inventors: Brian Chawke, Kieran Curran, David McGuire, Michael Sayers, Noel Sirr
  • Patent number: 9776182
    Abstract: Devices, systems and methods for making and handling liquid samples are disclosed.
    Type: Grant
    Filed: November 26, 2013
    Date of Patent: October 3, 2017
    Assignee: GenCell Biosystems Ltd.
    Inventors: Kieran Curran, David McGuire, Brian Chawke, Paul Fleming, Brian Barrett, Noel Sirr
  • Patent number: 9777269
    Abstract: Methods, devices and systems for handling sample liquids, encapsulating liquids and magnetic particles are disclosed.
    Type: Grant
    Filed: January 25, 2013
    Date of Patent: October 3, 2017
    Assignee: GenCell Biosystems Ltd.
    Inventors: Kieran Curran, David McGuire
  • Publication number: 20170130262
    Abstract: Aspects of the present disclosure include a complete genomic analysis device and methods of use thereof for high throughput genomic analysis of biological samples.
    Type: Application
    Filed: August 3, 2015
    Publication date: May 11, 2017
    Inventors: Mark Dalton, John Daly, Mark McCabe, Padraig Walsh, Kevin Daulnay, David McGuire, Maria Kerin, Maria O'Connor, Colin King, Keith Mooney
  • Publication number: 20160281135
    Abstract: Provided herein is a biological detection system and method of use wherein the biological detection system comprises at least one mixer or liquid bridge for combining at least two liquid droplets and an error correction system for detecting whether or not proper mixing or combining of the two component droplets have occurred.
    Type: Application
    Filed: February 26, 2016
    Publication date: September 29, 2016
    Inventors: Mauro Aguanno, Brian T. Chawke, Kieran Curran, Tara Dalton, Mark Davies, Xiaona Hou, David Kinahan, Mark Korenke, David McGuire, Michael Sayers, Noel Sirr, Ryan J. Talbot, Brian Barrett, Damian Curtin, Damien King, Conor McCarthy
  • Patent number: 9452007
    Abstract: A cannulated driver includes a handle, a barrel coupled to the handle, and a drive tip coupled to the barrel and having an outer surface and an engagement end that engages within a head of a cannulated screw. The driver is configured to removably retain a corresponding cannulated screw onto the driver. The drive tip includes a passageway disposed generally in a radial direction with respect to the driver's longitudinal axis. An engagement pin is movably mounted for travel in the passageway between an extended position wherein an exposable end of the pin protrudes radially beyond the outer surface of the drive tip and a retracted position wherein the pin does not thus protrude. In the extended position, the exposable end of the pin protrudes into a corresponding recess in the head of a special cannulated screw to removably retain the screw onto the driver.
    Type: Grant
    Filed: August 3, 2012
    Date of Patent: September 27, 2016
    Inventors: David A. McGuire, Bruce D. Sunstein
  • Publication number: 20160271606
    Abstract: Devices, systems, and methods for charging fluids are disclosed. The charging of fluids improves the mixing of fluids in microfluidic systems. The charging is performed by producing an ion field between an ionizing electrode and an opposed ground electrode. A fluid-containing vessel is positioned between the opposed electrodes and the ion field charges the fluid in the vessel.
    Type: Application
    Filed: February 19, 2016
    Publication date: September 22, 2016
    Inventors: Brian Chawke, Kieran Curran, David McGuire, Michael Sayers, Noel Sirr
  • Publication number: 20160193607
    Abstract: A single-use cartridge, wherein the cartridge defines a plurality of blind bores, each blind bore defining one opening at least one of the plurality of blind bores containing two mutually immiscible liquids, both of which are immiscible with water, one of the two mutually immiscible liquids having a specific gravity greater than water and the other of the two mutually immiscible liquids having a specific gravity less than water.
    Type: Application
    Filed: November 25, 2014
    Publication date: July 7, 2016
    Inventors: Brian Barrett, David McGuire, Robert Roeven