Patents by Inventor David A. Morgenstern

David A. Morgenstern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240272154
    Abstract: An in vitro method is disclosed for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby a complex comprising the p53 capture antigen, the anti-p53 antibody and the p53 detection antigen is formed, separating the complex formed from unbound detection antigen and measuring the complex obtained via the detection antigen comprised therein, thereby detecting the anti-p53 antibody comprised in the sample.
    Type: Application
    Filed: March 26, 2024
    Publication date: August 15, 2024
    Inventors: Herbert Andres, Johann Karl, Ursula Kunert, David Morgenstern, Nina Meissler, Marion Niessner, Magdalena Swiatek-de Lange
  • Patent number: 11971407
    Abstract: An in vitro method is disclosed for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby a complex comprising the p53 capture antigen, the anti-p53 antibody and the p53 detection antigen is formed, separating the complex formed from unbound detection antigen and measuring the complex obtained via the detection antigen comprised therein, thereby detecting the anti-p53 antibody comprised in the sample.
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: April 30, 2024
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Herbert Andres, Johann Karl, Ursula Kunert, David Morgenstern, Nina Meissler, Marion Niessner, Magdalena Swiatek-de Lange
  • Publication number: 20240114899
    Abstract: Herbicidal compositions for reducing off-site movement or drift of herbicides are described. The herbicidal compositions can include an auxin herbicide, an oil or an ester of the oil, and a polymeric emulsifying agent, such as glycerol ethoxylate-polyricinoleate, glycerol ethoxylate-poly-(12-hydroxystearate), polyethylene glycol (PEG)-polyricinoleate, PEG-poly-(12-hydroxystearate), and a combination thereof. Methods of making such compositions and methods of making such polymeric emulsifying agents are also described.
    Type: Application
    Filed: October 12, 2023
    Publication date: April 11, 2024
    Inventors: Jingsi GAO, Ganiyu JIMOH, Alison MACINNES, David A. MORGENSTERN
  • Publication number: 20240029819
    Abstract: Agents binding modified antigen dependent peptides and use of same are provided. Accordingly, there is provided an agent capable of specifically binding an MHC presented peptide comprising a post translational modification (PTM), wherein the agent does not bind a peptide having the same amino acid sequence as said peptide but does not comprise said modification. Also provided are polynucleotides encoding the agent, cells expressing same and methods of use thereof. Also provided is a computer implemented method for generating a dataset of PTM on MHC bound peptides.
    Type: Application
    Filed: April 27, 2023
    Publication date: January 25, 2024
    Applicant: Yeda Research and Development Co. Ltd.
    Inventors: Yifat MERBL, Assaf KACEN, Yishai LEVIN, David MORGENSTERN
  • Publication number: 20240016146
    Abstract: Herbicidal compositions for reducing off-site movement or drift of herbicides are described. The herbicidal compositions can include a drift retardant agent (DRA) along with at least one auxin herbicide and an emulsifying agent, such as an alkylpolysaccharide, a phosphate ester, an alkoxylated castor oil, or a combination thereof. Methods of making such composition are also described.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 18, 2024
    Applicant: Monsanto Technology LLC
    Inventors: Jingsi GAO, Alison MACINNES, David A. MORGENSTERN
  • Patent number: 11825840
    Abstract: Herbicidal compositions for reducing off-site movement or drift of herbicides are described. The herbicidal compositions can include an auxin herbicide, an oil or an ester of the oil, and a polymeric emulsifying agent, such as glycerol ethoxylate-polyricinoleate, glycerol ethoxylate-poly-(12-hydroxystearate), polyethylene glycol (PEG)-polyricinoleate, PEG-poly-(12-hydroxystearate), and a combination thereof. Methods of making such compositions and methods of making such polymeric emulsifying agents are also described.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: November 28, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Jingsi Gao, Ganiyu Jimoh, Alison MacInnes, David Morgenstern
  • Patent number: 11793195
    Abstract: Herbicidal compositions for reducing off-site movement or drift of herbicides are described. The herbicidal compositions can include a drift retardant agent (DRA) along with at least one auxin herbicide and an emulsifying agent, such as an alkylpolysaccharide, a phosphate ester, an alkoxylated castor oil, or a combination thereof. Methods of making such composition are also described.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: October 24, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Jingsi Gao, Alison Macinnes, David Morgenstern
  • Publication number: 20230305010
    Abstract: The present invention relates to an in vitro method for assessing cholangiocarcinoma in a patient sample, comprising the steps of: a) determining the level of tissue inhibitor of metalloproteinase-1 (TIMP1) in the patient sample, wherein the patient sample is selected from a group consisting of serum, plasma and whole blood sample from an individual, b) comparing the level of TIMP1 determined in step (a) with a reference level of TIMP1, and c) assessing cholangiocarcinoma in the patient sample by comparing the level determined in step (a) to the reference level of TIMP1, wherein an increased level of TIMP1 compared to the reference level of TIMP1 is indicative for cholangiocarcinoma in the patient sample. Further, the present invention relates to an in vitro method for assessing cholangiocarcinoma comprising TIMP1 and MMP2, the use of TIMP1 and optionally MMP2 in the in vitro assessment of CCA, and a kit for performing the said methods.
    Type: Application
    Filed: May 1, 2023
    Publication date: September 28, 2023
    Inventors: Farshid Dayyani, Anika Mang, David Morgenstern, Vinzent Rolny, Magdalena Swiatek-De Lange
  • Patent number: 11730099
    Abstract: The invention provides novel compositions and methods for liquid-mediated delivery of pollen to a female reproductive part of a recipient plant. The pollen suspension solutions provided include a surfactant, an oil, a solute, or an aqueous solution, and about 2% to about 20% pollen by weight. The methods provided include producing a liquid pollen suspension solution comprising pollen from a donor plant and spraying the solution onto at least a first female reproductive part of a recipient plant, thereby pollinating the female reproductive part with the pollen from the donor plant.
    Type: Grant
    Filed: March 31, 2021
    Date of Patent: August 22, 2023
    Assignee: Monsanto Technology LLC
    Inventors: Zachary Boyer, David A. Morgenstern, Michelle R. Naert
  • Patent number: 11698185
    Abstract: An invisible, light-transmissive display system with a light resistant material is provided. Substantially invisible, tapered, light-transmissive holes are penetrated in a light transmissive pattern through at least a portion of the light resistant material using a laser beam having a focal width less than the smallest diameter of the tapered holes.
    Type: Grant
    Filed: January 10, 2022
    Date of Patent: July 11, 2023
    Assignee: Apple Inc.
    Inventors: Bartley K. Andre, Daniel J. Coster, Richard P. Howarth, Daniele de Iuliis, Jonathan P. Ive, Duncan Robert Kerr, Shin Nishibori, Matthew Dean Rohrbach, Douglas B. Satzger, Calvin Q. Seid, Christopher J. Stringer, Eugene Anthony Whang, Rico Zorkendorfer, David Morgenstern, Paul C. L. Chow
  • Publication number: 20230072943
    Abstract: A utility knife is disclosed, including a housing having a handle portion and a front end. A first wing and a second wing are each pivotally engaged with the handle portion. The first wing and the second wing guide at least one blade along an edge of a box when cutting and disassembling the box. A trigger extends and retract the at least one blade such that the blade(s) are only extended during use to protect the user.
    Type: Application
    Filed: September 9, 2022
    Publication date: March 9, 2023
    Inventors: Andres Hausmann, Eduardo Saias, David Morgenstern, Leonardo Lustgarten
  • Publication number: 20220400637
    Abstract: The invention provides novel systems and methods for liquid-mediated delivery of pollen to a female reproductive part of a recipient plant. The systems provided herein include a container configured to receive a liquid pollen suspension solution, and an applicator attached to the container configured to spray the liquid pollen suspension solution onto the recipient plant. The methods provided herein include spraying a liquid pollen suspension solution onto at least a first female reproductive part of a recipient plant using the system provided herein, thereby pollinating the recipient plant.
    Type: Application
    Filed: February 25, 2022
    Publication date: December 22, 2022
    Inventors: Eric L. Borrowman, David A. Morgenstern
  • Patent number: 11465960
    Abstract: The present invention relates to esters of carboxylic acid agrochemicals comprising a labile protecting group and having formula (I). Certain of the esters of carboxylic acid agrochemicals do not undergo hydrolysis to a significant degree in the dark, but are cleaved to regenerate the parent carboxylic acid agrochemical when exposed to light. Others of the esters of carboxylic acid agrochemicals undergo hydrolysis under both light and dark conditions. The present invention further relates to methods for the controlled release of a carboxylic acid agrochemicals, and to methods of controlling unwanted plants comprising applying to the unwanted plants an ester of a carboxylic acid agrochemical.
    Type: Grant
    Filed: September 1, 2020
    Date of Patent: October 11, 2022
    Assignee: Monsanto Technology LLC
    Inventor: David A. Morgenstern
  • Publication number: 20220252592
    Abstract: The disclosure relates to an in vitro method for detecting an antibody to p53 (anti-p53 antibody) in a sample, the method comprising: incubating a sample to be analyzed with a p53 capture antigen and a p53 detection antigen, whereby a complex comprising the p53 capture antigen, the anti-p53 antibody and the p53 detection antigen is formed, separating the complex formed from unbound detection antigen and measuring the complex obtained via the detection antigen comprised therein, thereby detecting the anti-p53 antibody comprised in the sample.
    Type: Application
    Filed: April 27, 2022
    Publication date: August 11, 2022
    Inventors: Herbert Andres, Johann Karl, Ursula Kunert, David Morgenstern, Nina Meissler, Marion Niessner, Magdalena Swiatek-de Lange
  • Publication number: 20220128228
    Abstract: An invisible, light-transmissive display system with a light resistant material is provided. Substantially invisible, tapered, light-transmissive holes are penetrated in a light transmissive pattern through at least a portion of the light resistant material using a laser beam having a focal width less than the smallest diameter of the tapered holes.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Inventors: Bartley K. Andre, Daniel J. Coster, Richard P. Howarth, Daniele de Iuliis, Jonathan P. Ive, Duncan Robert Kerr, Shin Nishibori, Matthew Dean Rohrbach, Douglas B. Satzger, Calvin Q. Seid, Christopher J. Stringer, Eugene Anthony Whang, Rico Zorkendorfer, David Morgenstern, Paul C.L. Chow
  • Patent number: 11236895
    Abstract: An invisible, light-transmissive display system with a light resistant material is provided. Substantially invisible, tapered, light-transmissive holes are penetrated in a light transmissive pattern through at least a portion of the light resistant material using a laser beam having a focal width less than the smallest diameter of the tapered holes.
    Type: Grant
    Filed: July 1, 2020
    Date of Patent: February 1, 2022
    Assignee: Apple Inc.
    Inventors: Bartley K. Andre, Daniel J. Coster, Richard P. Howarth, Daniele de Iuliis, Jonathan P. Ive, Duncan Robert Kerr, Shin Nishibori, Matthew Dean Rohrbach, Douglas B. Satzger, Calvin Q. Seid, Christopher J. Stringer, Eugene Anthony Whang, Rico Zorkendorfer, David Morgenstern, Paul C. L. Chow
  • Publication number: 20210388294
    Abstract: The present invention generally relates to methods of cleaning residual pesticide from an agricultural vessel, and to kits and compositions useful for the practice of such methods.
    Type: Application
    Filed: July 8, 2021
    Publication date: December 16, 2021
    Applicant: Monsanto Technology LLC
    Inventors: Amanda C. Herr, David A. Morgenstern, James W. Taylor
  • Publication number: 20210307273
    Abstract: The invention provides novel compositions and methods for liquid-mediated delivery of pollen to a female reproductive part of a recipient plant. The pollen suspension solutions provided include a surfactant, an oil, a solute, or an aqueous solution, and about 2% to about 20% pollen by weight. The methods provided include producing a liquid pollen suspension solution comprising pollen from a donor plant and spraying the solution onto at least a first female reproductive part of a recipient plant, thereby pollinating the female reproductive part with the pollen from the donor plant.
    Type: Application
    Filed: March 31, 2021
    Publication date: October 7, 2021
    Inventors: Zachary Boyer, David A. Morgenstern, Michelle R. Naert
  • Patent number: 11134675
    Abstract: This disclosure provides compositions and methods for delivery of a polynucleotide to an organism. More specifically, this disclosure relates to compositions including a mixture of a polynucleotide and a cationic polysaccharide, and methods of providing such compositions to an organism, such as a pest (e.g., an insect, a nematode, a mollusk).
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: October 5, 2021
    Assignee: MONSANTO TECHNOLOGY LLC
    Inventors: David A. Morgenstern, Lamtho L. Nguyen Ohtake
  • Patent number: 11091725
    Abstract: The present invention generally relates to methods of cleaning residual pesticide from an agricultural vessel, and to kits and compositions useful for the practice of such methods.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: August 17, 2021
    Assignee: Monsanto Technology LLC
    Inventors: Amanda C. Herr, David A. Morgenstern, James W. Taylor