Abstract: The disclosure provides compositions comprising novel adenosine base editors (e.g., ABE8) that have increased efficiency and methods of using these adenosine deaminase variants for editing a target sequence.

Abstract: A plumbing tool assembly for removing a cartridge housing from a valve body includes a pair of pliers which has of jaws that are urgeable toward or away from each other. A pair of panels is each coupled to a respective one of the pair of jaws of the pliers. A pair of grips is each attached to a respective one of the panels. Each of the grips has a scallop to accommodate a cartridge housing on a valve body of a shower faucet. The scallop in each of the grips is aligned with each other to facilitate the pair of grips to be closed around the cartridge housing for removing the cartridge housing from the valve body.

Abstract: A system for improving efficiency in which water or aqueous solution is broken into its core molecules of hydrogen and oxygen using a 12 volt power source, and of which this gas vapor can improve the efficiency of an engine of a vehicle in a catalytic fashion once combining with a fossil fuel, and includes a reactor housing containing at least one reactor unit having electrodes slotted in an insulated container, a solution supply system that regulates the aqueous solution in the system; and an air handling system that regulates the decomposed hydrogen and oxygen gas in the system. The reactor unit being immersed in an liquid or aqueous solution produces hydrogen and oxygen through electrolysis.

Abstract: A system for improving efficiency in which water or aqueous solution is broken into its core molecules of hydrogen and oxygen using a 12 volt power source, and of which this gas vapor can improve the efficiency of an engine of a vehicle in a catalytic fashion once combining with a fossil fuel, and includes a reactor housing containing at least one reactor unit having electrodes slotted in an insulated container, a solution supply system that regulates the aqueous solution in the system; and an air handling system that regulates the decomposed hydrogen and oxygen gas in the system. The reactor unit being immersed in an liquid or aqueous solution produces hydrogen and oxygen through electrolysis.

Abstract: Systems and methods for receiving used asphalt materials, heating the materials, dynamically tumbling the materials into a recycled granulized form, and selectively providing the recycled asphalt for use. An asphalt recycling system is used that is configured to receive used asphalt materials, including RAP and asphalt chunks. Inside the system, the asphalt materials are heated in a heating chamber, such as by natural gas, propane, or another heat source. The heating chamber warms the metal in the chute, and material in the chute can be exposed to exhaust gas, which preheats the asphalt material. The material is then delivered through the chute and onto a conveyer belt, which drops down into a rotating drum. The drum includes a material classifier ring and a plurality of paddles that are used to tumble the heated asphalt material until it becomes generally granularized. The drum can be manipulated (e.g., tilted, etc.

Abstract: Systems and methods for receiving used asphalt materials, heating the materials, dynamically tumbling the materials into a recycled granulized form, and selectively providing the recycled asphalt for use. An asphalt recycling system is used that is configured to receive used asphalt materials, including RAP and asphalt chunks. Inside the system, the asphalt materials are heated in a heating chamber, such as by natural gas, propane, or another heat source. The heating chamber warms the metal in the chute, and material in the chute can be exposed to exhaust gas, which preheats the asphalt material. The material is then delivered through the chute and onto a conveyer belt, which drops down into a rotating drum. The drum includes a material classifier ring and a plurality of paddles that are used to tumble the heated asphalt material until it becomes generally granularized. The drum can be manipulated (e.g., tilted, etc.

Abstract: Systems and methods for receiving used asphalt materials, heating the materials, dynamically tumbling the materials into a recycled granulized form, and selectively providing the recycled asphalt for use. An asphalt recycling system is used that is configured to receive used asphalt materials, including RAP and asphalt chunks. Inside the system, the asphalt materials are heated in a heating chamber, such as by natural gas, propane, or another heat source. The heating chamber warms the metal in the chute, and material in the chute can be exposed to exhaust gas, which preheats the asphalt material. The material is then delivered through the chute and onto a conveyer belt, which drops down into a rotating drum. The drum includes a material classifier ring and a plurality of paddles that are used to tumble the heated asphalt material until it becomes generally granularized. The drum can be manipulated (e.g., tilted, etc.

Abstract: Systems and methods for receiving used asphalt materials, heating the materials, dynamically tumbling the materials into a recycled granulized form, and selectively providing the recycled asphalt for use. An asphalt recycling system is used that is configured to receive used asphalt materials, including RAP and asphalt chunks. Inside the system, the asphalt materials are heated in a heating chamber, such as by natural gas, propane, or another heat source. The heating chamber warms the metal in the chute, and material in the chute can be exposed to exhaust gas, which preheats the asphalt material. The material is then delivered through the chute and onto a conveyer belt, which drops down into a rotating drum. The drum includes a material classifier ring and a plurality of paddles that are used to tumble the heated asphalt material until it becomes generally granularized. The drum can be manipulated (e.g., tilted, etc.