Abstract: A carton forming machine includes a carton blank push up device that receives a substantially horizontal folded carton blank and reorients the folded carton blank from the substantially horizontal orientation to an upright orientation below and in a first direction alignment with a carton opening mechanism. A carton blank positioning apparatus shifts the upright folded carton blank in a second direction, transverse to the first direction, below the carton opening mechanism to define a second direction position of the upright carton blank below the carton opening mechanism before the carton opening mechanism engages the upright carton blank for opening of the upright carton blank.

Abstract: A carton forming machine includes a carton blank push up device that receives a substantially horizontal folded carton blank and reorients the folded carton blank from the substantially horizontal orientation to an upright orientation below and in a first direction alignment with a carton opening mechanism. A carton blank positioning apparatus shifts the upright folded carton blank in a second direction, transverse to the first direction, below the carton opening mechanism to define a second direction position of the upright carton blank below the carton opening mechanism before the carton opening mechanism engages the upright carton blank for opening of the upright carton blank.

Abstract: A newly identified gene, DIS1 is disrupted by a (1;11)(q42.1;q14.3) translocation which segregates with schizophrenia. We have examined the genomic structure of DIS1 and found that the gene consists of 13 exons estimated to extend across at least 300 kb of DNA. Exon 11 contains an alternative splice site which removes 66 nucleotides from the open reading frame. The final intron of DIS1 belongs to the rare AT-AC class of introns. 8 expressed sequence tags (ESTs) located within introns 3, 7, 9 and 10 of DIS1 have also been identified. These ESTs have not yet been assigned to DIS1 and may therefore represent further novel genes in the region.

Abstract: The present invention relates to the identification of genes which have been disrupted in patients diagnosed as suffering from schizophrenia and/or bi-polar affective disorder, as well as proteins encoded by the gene and antibodies thereto and to uses of such products as medicaments for treating schizophrenia and/or affective psychosis. The invention also relates to methods for diagnosing, patients suffering or predisposed to schizophrenia and/or affective psychosis, as well as screens for developing novel treatment regimes for schizophrenia and/or affective psychosis.

Abstract: A test connector for connecting an air brake test device to access ports of an air brake control valve device where such access ports are normally closed by check valves. A plurality of actuator devices corresponding in number to the access ports are provided in the test connector to unseat the check valves and conduct test air to the test device via central passages in the actuators. The actuators are piston operated in response to a pilot pressure received from a source of compressed air remote from the connector.

Abstract: A hydro-pneumatic brake actuator arranged with a slack adjuster piston and one-way check valve device in the hydraulic path between a hydro-pneumatic actuator and a power piston, to which a friction brake element is connected for engagement with a vehicle wheel tread or brake disc during a brake application. During a brake release, the one-way check valve closes a passage through the slack adjuster piston to cause the piston to shift from its one extreme position to the other extreme position with the fluid flow, as the hydro-pneumatic actuator is moved from its application position to its release position. This in turn draws hydraulic fluid from the power piston chamber into a clearance volume created by shifting of the slack adjuster piston, and accordingly forces the power piston to retract a predetermined distance corresponding to the capacity of the clearance volume and the effective area of the power piston, thereby maintaining a constant brake shoe clearance during brake release.