Abstract: The present invention relates to GH61 polypeptide variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.

Abstract: A vehicle operable by an unrestrained or uncontained rider and including a controller programmed to identify a trigger for an autonomous vehicle response. A sensor of the vehicle is in communication with the controller and operable to detect a predefined condition as the trigger. A rider sensor system in communication with the controller includes one or both of: a rider cognition sensor, and a rider physical sensor to detect physical engagement between rider and vehicle. On the condition of the controller determining from the rider sensor system that there is positive rider engagement, the controller is programmed to instruct a first level of autonomous vehicle response to the one or more actuators to effect a change in the operation of the vehicle in response to identification of the trigger. In the absence of positive rider engagement determined by the controller, the first level of autonomous vehicle response is prohibited.

Abstract: A saddle-ride vehicle includes a forward travel sensor a brake that decelerates the vehicle by actuation of a rider-operable brake control. A controller identifies a trigger for an autonomous braking event for the brake. A rider sensor system is in electrical communication with the controller and includes one or both of: a rider cognition sensor operable to detect parameters of rider cognition and report rider cognition status to the controller, and a rider physical sensor operable to detect parameters of a physical engagement between a rider and the vehicle and report rider physical engagement status to the controller. The controller is programmed to perform one or both of the following in response to the identification of the autonomous braking event trigger: checking for a positive cognitive engagement of the rider with the rider cognition sensor, and checking for a positive physical engagement of the rider with the rider physical sensor.

Abstract: A system and method for holding, transporting, and tracking electronically tagged objects maintained in a portable carrier housing includes a locking mechanism for enabling limited authorized access using a proximity sensor recognizing an identity code of an authorized user, a location tracker for detecting the location of the portable carrier, and an inventory logger registering placement and removal of the electronically tagged objects within and out of the portable carrier housing, registering the location of the portable carrier housing at a time of placement or removal of the electronically tagged object, and registering the identity code of the authorized user within proximity of the proximity sensor. The system further includes a transmitter for uploading data from the inventory logger to a database and a receiver for at least receiving instructions for locking the portable carrier housing when detecting an attempted unauthorized access or detecting a condition indicative of unauthorized access.

Abstract: A system and method for holding, transporting, and tracking electronically tagged objects maintained in a portable carrier housing includes a locking mechanism for enabling limited authorized access using a proximity sensor recognizing an identity code of an authorized user, a location tracker for detecting the location of the portable carrier, and an inventory logger registering placement and removal of the electronically tagged objects within and out of the portable carrier housing, registering the location of the portable carrier housing at a time of placement or removal of the electronically tagged object, and registering the identity code of the authorized user within proximity of the proximity sensor. The system further includes a transmitter for uploading data from the inventory logger to a database and a receiver for at least receiving instructions for locking the portable carrier housing when detecting an attempted unauthorized access or detecting a condition indicative of unauthorized access.

Abstract: Change tracking and collaborative communication are provided in authoring content in a collaborative environment. Monitored changes, comments, and similar input by the collaborating authors may be presented on demand or automatically to each author based on changes and/or comments that affect a particular author, that author's portion of collaborated content, type of changes/comments, or similar criteria. Change and/or comments notification may be provided in a complementary user interface of the collaborative authoring application or through a separate communication application such as email or text messaging.

Abstract: A saddle-ride vehicle includes a forward travel sensor a brake that decelerates the vehicle by actuation of a rider-operable brake control. A controller identifies a trigger for an autonomous braking event for the brake. A rider sensor system is in electrical communication with the controller and includes one or both of: a rider cognition sensor operable to detect parameters of rider cognition and report rider cognition status to the controller, and a rider physical sensor operable to detect parameters of a physical engagement between a rider and the vehicle and report rider physical engagement status to the controller. The controller is programmed to perform one or both of the following in response to the identification of the autonomous braking event trigger: checking for a positive cognitive engagement of the rider with the rider cognition sensor, and checking for a positive physical engagement of the rider with the rider physical sensor.

Abstract: A method of conducting a diagnostic procedure for a braking system includes analyzing via an electronic control unit whether only a first input device is engaged or only a second input device is engaged, conducting a first diagnostic test if only the first input device is engaged, and conducting a second diagnostic test if only the second input device is engaged.

Abstract: Change tracking and collaborative communication are provided in authoring content in a collaborative environment. Monitored changes, comments, and similar input by the collaborating authors may be presented on demand or automatically to each author based on changes and/or comments that affect a particular author, that author's portion of collaborated content, type of changes/comments, or similar criteria. Change and/or comments notification may be provided in a complementary user interface of the collaborative authoring application or through a separate communication application such as email or text messaging.

Abstract: Change tracking and collaborative communication are provided in authoring content in a collaborative environment. Monitored changes, comments, and similar input by the collaborating authors may be presented on demand or automatically to each author based on changes and/or comments that affect a particular author, that author's portion of collaborated content, type of changes/comments, or similar criteria. Change and/or comments notification may be provided in a complementary user interface of the collaborative authoring application or through a separate communication application such as email or text messaging.

Abstract: A saddle-ride vehicle includes a forward travel sensor a brake that decelerates the vehicle by actuation of a rider-operable brake control. A controller identifies a trigger for an autonomous braking event for the brake. A rider sensor system is in electrical communication with the controller and includes one or both of: a rider cognition sensor operable to detect parameters of rider cognition and report rider cognition status to the controller, and a rider physical sensor operable to detect parameters of a physical engagement between a rider and the vehicle and report rider physical engagement status to the controller. The controller is programmed to perform one or both of the following in response to the identification of the autonomous braking event trigger: checking for a positive cognitive engagement of the rider with the rider cognition sensor, and checking for a positive physical engagement of the rider with the rider physical sensor.

Abstract: A method of conducting a diagnostic procedure for a braking system includes analyzing via an electronic control unit whether only a first input device is engaged or only a second input device is engaged, conducting a first diagnostic test if only the first input device is engaged, and conducting a second diagnostic test if only the second input device is engaged.

Abstract: A saddle-ride vehicle includes a forward travel sensor a brake that decelerates the vehicle by actuation of a rider-operable brake control. A controller identifies a trigger for an autonomous braking event for the brake. A rider sensor system is in electrical communication with the controller and includes one or both of: a rider cognition sensor operable to detect parameters of rider cognition and report rider cognition status to the controller, and a rider physical sensor operable to detect parameters of a physical engagement between a rider and the vehicle and report rider physical engagement status to the controller. The controller is programmed to perform one or both of the following in response to the identification of the autonomous braking event trigger: checking for a positive cognitive engagement of the rider with the rider cognition sensor, and checking for a positive physical engagement of the rider with the rider physical sensor.

Abstract: A saddle-ride vehicle includes a forward travel sensor a brake that decelerates the vehicle by actuation of a rider-operable brake control. A controller identifies a trigger for an autonomous braking event for the brake. A rider sensor system is in electrical communication with the controller and includes one or both of: a rider cognition sensor operable to detect parameters of rider cognition and report rider cognition status to the controller, and a rider physical sensor operable to detect parameters of a physical engagement between a rider and the vehicle and report rider physical engagement status to the controller. The controller is programmed to perform one or both of the following in response to the identification of the autonomous braking event trigger: checking for a positive cognitive engagement of the rider with the rider cognition sensor, and checking for a positive physical engagement of the rider with the rider physical sensor.

Abstract: Novel methods for the production of iron, silicon, and magnesium metal from extraterrestrial and terrestrial resources are described. The methods employ processing steps including metal oxide reduction using carbon monoxide, carbon, hydrogen, and methane. Methods to prepare, regenerate, and recycle reductants to minimize mining and purchase of fresh materials and to minimize carbon emissions are included.

Abstract: An auxiliary system for cooling a spent nuclear fuel pool through a submersible heat exchanger to be located within the pool. In each train or installation, a single loop or series of loops of cooling fluid (e.g., sea water or service water) is circulated. The system is modular, readily and easily installed during an emergency and can be self operating with its own power source. Multiple trains may be used in parallel in order to accomplish the required degree of spent fuel pool cooling required.

Abstract: Real-time co-authoring and support for the collaborative process is enabled by making it easy to initiate a collaborative document, to invite the proper people into the process, to collect existing artifacts, thoughts, and research, and then to divide and track the work to completion across a collaborating group. Monitored changes, comments, and similar input by the collaborating authors may be presented on demand or automatically to each author based on changes and/or comments that affect a particular author, that author's portion of collaborated content, type of changes/comments, or similar criteria Real-time or sequential communication such as email, text messaging, and video chat, may be enabled to further optimize the collaboration process.

Abstract: To employ presence-based history information in conjunction with a notebook application, presence information for one or more users associated with a notebook application is determined from a variety of presence services. One or more interactions of the users are tracked in conjunction with a location within the notebook to record history information associated with the one or more users. The history information may be presented to the users through a user interface in conjunction with a location within the notebook application or through a separate user interface. The presented history information may include the recorded history information and statistical information based on the recorded history information. The users may interact with the user interface to employ the presented presence-based history information in conjunction with contents of the notebook application. For example, replay of user interactions in conjunction with a location within the notebook application may be enabled.

Abstract: Recent developments in cost-effective DNA sequencing allows for individualized genomic screening of a subject for genetic sequence variants. Training a pathogenicity prediction model using semi-supervised training methods produces a better model for predicting the pathogenicity of a test genetic sequence variant. Provided herein are methods for predicting the pathogenicity of a test genetic sequence variant by utilizing a training data set comprising labeled benign genetic sequence variants unlabeled genetic sequence variants, the unlabeled genetic sequence variants comprising a mixture of benign genetic sequence variants and pathogenic genetic sequence variants. The genetic sequences are annotated with one or more features and a machine learning model is trained in a semi-supervised process based on the training data.

Abstract: To employ presence information in conjunction with a notebook application, presence information is determined for one or more users associated with a notebook application. The presence information may be obtained from a variety of sources, such as a communication application, a social or professional network, and a presence module of the notebook application. Once determined, the presence information is presented to the users through a user interface in conjunction with a location within the notebook application or through a separate user interface. The notebook application may further track the presence information for the users interacting with the notebook application. The users may then be enabled to interact with the user interface to use the presented presence information in conjunction with content maintained by the notebook application.