Abstract: Provided herein is a topical antibiotic composition that includes an external antibiotic agent, one or more pharmaceutically acceptable excipients, and at least one of a cannabinoid, terpene, and flavonoid. Also provided is a method that includes topically administering to a skin surface of a subject (e.g., human) the topical antibiotic composition.

Abstract: Provided herein is a topical cosmetic composition that includes an external cosmetic agent, one or more pharmaceutically acceptable excipients, and at least one of a cannabinoid, terpene, and flavonoid. Also provided is a method that includes topically administering to a skin surface of a subject (e.g., human) the topical cosmetic composition.

Abstract: The disclosure provides a selective inhibitor of DNA-binding to poly (ADP-ribose) polymerase 1 (PARP1), or a pharmaceutically acceptable salt or solvate thereof, for use in treating, ameliorating or preventing cancer. The treatment may be given to a subject suffering from or at risk of osteoporosis or a subject requiring a long-term therapy.

Abstract: Provided herein is a topical analgesic composition that includes an external analgesic agent, one or more pharmaceutically acceptable excipients, and at least one of a cannabinoid, terpene, and flavonoid. Also provided is a method that includes topically administering to a skin surface of a subject (e.g., human) the topical analgesic composition.

Abstract: Provided is an oral soft gel capsule that includes a psychedelic compound. Also provided is a method of treating in a subject a disease or disorder ameliorated by a psychedelic compound, that includes orally administering to a subject an oral soft gel capsule that includes a therapeutically effective amount of the psychedelic compound. Also provided is a method of orally administering to a subject an oral soft gel capsule that includes a therapeutically effective amount of the psychedelic compound. Also provided is a method of orally administering to a subject an oral soft gel capsule that includes a low dose (e.g., microdose or sub-therapeutic dose) of the psychedelic compound.

Abstract: Provided is an oral dissolvable film that includes a psychedelic compound. Also provided is a method of treating in a subject a disease or disorder ameliorated by a psychedelic compound, that includes orally administering to a subject an oral dissolvable film that includes a therapeutically effective amount of the psychedelic compound. Also provided is a method of orally administering to a subject an oral dissolvable film that includes a therapeutically effective amount of the psychedelic compound. Also provided is a method of orally administering to a subject an oral dissolvable film that includes a low dose (e.g., microdose or sub-therapeutic dose) of the psychedelic compound.

Abstract: A lean NOx trap catalyst and its use in an emission treatment system for internal combustion engines is disclosed. The lean NOx trap catalyst comprises a first layer for storing nitrogen oxides (NOx) under lean exhaust gas conditions and releasing and/or reducing stored NOx during rich exhaust gas conditions, and a second layer, said second layer comprising a first zone for oxidizing carbon monoxide (CO) and/or hydrocarbons (HC), and a second zone for oxidizing nitric oxide (NO), and a substrate having an inlet end and an outlet end.

Abstract: The presently disclosed subject matter relates to a multilayer nonwoven material. More particularly, the presently disclosed subject matter relates to multilayered structures including, but not limited to, two, three, or four layers to form the nonwoven material. The multilayered structure can include a first layer comprising continuous filaments and a second layer comprising bonded fibers. The continuous filaments can be synthetic filaments. The fibers can be cellulosic fibers, noncellulosic fibers, or combinations thereof. Certain layers can also contain a binder material.

Abstract: In one aspect, an apparatus includes a plating cell, a degassing device configured to remove oxygen from the plating solution prior to the plating solution flowing into the plating cell; an oxidation station configured to increase an oxidizing strength of the plating solution after the plating solution flows out of the plating cell; and a controller. The controller includes program instructions for causing a process that includes operations of: reducing an oxygen concentration of the plating solution where the plating solution contains a plating accelerator; then, contacting a wafer substrate with the plating solution having reduced oxygen concentration and electroplating a metal such that the electroplating causes a net conversion of the accelerator to a less-oxidized accelerator species within the plating cell; then increasing the oxidizing strength of the plating solution causing a net re-conversion of the less-oxidized accelerator species back to the accelerator outside the plating cell.

Abstract: A NOx adsorber catalyst and its use in an emission treatment system for internal combustion engines, is disclosed. The NOx adsorber catalyst comprises a first layer consisting essentially of a support material, one or more platinum group metals disposed on the support material, and a NOx storage material.

Abstract: A lean NOx trap catalyst and its use in an emission treatment system for internal combustion engines is disclosed. The lean NOx trap catalyst comprises a first layer, a second layer, and a third layer.

Abstract: A lean NOx trap catalyst and its use in an emission treatment system for internal combustion engines is disclosed. The lean NOx trap catalyst comprises a first layer, a second layer, and a third layer.

Abstract: A method for controlling the application of aircraft wheel brakes including: controlling the application of a first wheel brake of an aircraft and a second wheel brake of the aircraft in dependence upon a determined relationship to control the time taken for the first wheel brake and the second wheel brake to reach respective specified temperatures. The relationship is determined between a first cooling characteristic of the first wheel brake, according to which the first wheel brake cools when in a first retracted position within the aircraft, and a second cooling characteristic of the second wheel brake, according to which the second wheel brake cools when in a second retracted position within the aircraft.

Abstract: An exhaust system for treating an exhaust gas from an internal combustion engine is disclosed. The system comprises a modified lean NOx trap (LNT), a urea injection system, and an ammonia-selective catalytic reduction catalyst. The modified LNT comprises a first layer and a second layer. The first layer comprises a NOx adsorbent component and one or more platinum group metals. The second layer comprises a diesel oxidation catalyst zone and an NO oxidation zone. The diesel oxidation catalyst zone comprises a platinum group metal, a zeolite, and optionally an alkaline earth metal. The NO oxidation zone comprises a platinum group metal and a carrier. The modified LNT stores NOx at temperatures below about 200° C. and releases at temperatures above about 200° C. The modified LNT and a method of using the modified LNT are also disclosed.

Abstract: A NOx trap catalyst is disclosed. The NOx trap catalyst comprises a noble metal, a NOx storage component, a support, and a first ceria-containing material. The first ceria-containing material is pre-aged prior to incorporation into the NOx trap catalyst, and may have a surface area of less than 80 m2/g. The invention also includes exhaust systems comprising the NOx trap catalyst, and a method for treating exhaust gas utilizing the NOx trap catalyst.

Abstract: Methods and apparatus for determining whether a substrate includes an unacceptably high amount of oxide on its surface are described. The substrate is typically a substrate that is to be electroplated. The determination may be made directly in an electroplating apparatus, during an initial portion of an electroplating process. The determination may involve immersing the substrate in electrolyte with a particular applied voltage or applied current provided during or soon after immersion, and recording a current response or voltage response over this same timeframe. The applied current or applied voltage may be zero or non-zero. By comparing the current response or voltage response to a threshold current, threshold voltage, or threshold time, it can be determined whether the substrate included an unacceptably high amount of oxide on its surface. The threshold current, threshold voltage, and/or threshold time may be selected based on a calibration procedure.

Abstract: An electroplating apparatus for filling recessed features on a semiconductor substrate includes a vessel configured to maintain a concentrated electroplating solution at a temperature of at least about 40° C., wherein the solution would have formed a precipitate at 20° C. This vessel is in fluidic communication with an electroplating cell configured for bringing the concentrated electrolyte in contact with the semiconductor substrate at a temperature of at least about 40° C., or the vessel is the electroplating cell. In order to prevent precipitation of metal salts from the electrolyte, the apparatus further includes a controller having program instructions for adding a diluent to the concentrated electroplating solution in the vessel to avoid precipitation of a salt from the concentrated electroplating solution in response to a signal indicating that the electrolyte is at risk of precipitation.

Abstract: Methods and apparatus for determining whether a substrate includes an unacceptably high amount of oxide on its surface are described. The substrate is typically a substrate that is to be electroplated. The determination may be made directly in an electroplating apparatus, during an initial portion of an electroplating process. The determination may involve immersing the substrate in electrolyte with a particular applied voltage or applied current provided during or soon after immersion, and recording a current response or voltage response over this same timeframe. The applied current or applied voltage may be zero or non-zero. By comparing the current response or voltage response to a threshold current, threshold voltage, or threshold time, it can be determined whether the substrate included an unacceptably high amount of oxide on its surface. The threshold current, threshold voltage, and/or threshold time may be selected based on a calibration procedure.

Abstract: A leg brace isolates a lower extremity of a leg to which the brace is secured. The leg brace includes an upper leg cuff and a lower leg cuff. Two upper struts are attached to opposite sides of the upper leg cuff and extend along the upper leg cuff. Two lower struts are attached to opposite sides of the lower leg cuff and extend along the lower leg cuff. One hinge pivotally connects one upper strut and one lower strut and a second hinge pivotally connects the other upper strut and the other lower strut. The hinges can be configured to have a limited and/or selectable degree of rotation (e.g., flexion and/or extension). Bottom ends of the lower struts extend beyond a user's foot of the leg to which the leg brace is attached. A foot is attached to each bottom end of the lower struts.

Abstract: A dielectric composite material includes an electrical insulator and primary nanoparticles. The primary nanoparticles are dispersed, without forming agglomerates, within the electrical insulator.