Abstract: Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ER?) agonists. In some examples, the compounds can be selective ER? agonists. Also provided herein are methods of treating, preventing, or ameliorating cancer in a subject, suppressing tumor growth in a subject, treating an inflammatory disease in a subject, treating a neurodegenerative disease in a subject, treating a psychotropic disorder in a subject, or a combination thereof, by administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ER?) agonists. In some examples, the compounds can be selective ER? agonists. Also provided herein are methods of treating, preventing, or ameliorating cancer in a subject, suppressing tumor growth in a subject, treating an inflammatory disease in a subject, treating a neurodegenerative disease in a subject, treating a psychotropic disorder in a subject, or a combination thereof, by administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof.

Abstract: Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ER?) agonists. In some examples, the compounds can be selective ER? agonists. Also provided herein are methods of treating, preventing, or ameliorating cancer in a subject, suppressing tumor growth in a subject, treating an inflammatory disease in a subject, treating a neurodegenerative disease in a subject, treating a psychotropic disorder in a subject, or a combination thereof by administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof.

Abstract: 15?-substituted derivatives of estrone of general formula I wherein R1, R2, R3, R4, R5 are independently selected from the group consisting of: C1-C4 alkyl, C1-C4 alkoxy, C1-C4 halogenalkyl, halogen, COOR6 wherein R6 is C1-C4 alkyl; H, OH; optionally, R3, R4 and R5 are each formed by a hydrogen atom, while R1 and R2 together form an aryl group, preferably naphthyl, in which the aromatic ring in position C-15 can be mono-, di-, tri-, tetra- and penta-substituted with substituents R1-R5. Compounds of the invention may be used for diagnosis and possibly also for the treatment of estrogen-dependent diseases.

Abstract: 15?-substituted derivatives of estrone of general formula I wherein R1, R2, R3, R4, R5 are independently selected from the group consisting of: C1-C4 alkyl, C1-C4 alkoxy, C1-C4 halogenalkyl, halogen, COOR6 wherein R6 is C1-C4 alkyl; H, OH; optionally, R3, R4 and R5 are each formed by a hydrogen atom, while R1 and R2 together form an aryl group, preferably naphthyl, in which the aromatic ring in position C-15 can be mono-, di-, tri-, tetra- and penta-substituted with substituents R1-R5. Compounds of the invention may be used for diagnosis and possibly also for the treatment of estrogen-dependent diseases.

Abstract: Disclosed herein are compounds comprising dicarba-closo-dodecaborane. The compounds can be, for example, estrogen receptor beta (ER?) agonists. In some examples, the compounds can be selective ER? agonists. Also provided herein are methods of treating, preventing, or ameliorating cancer in a subject, suppressing tumor growth in a subject, treating an inflammatory disease in a subject, treating a neurodegenerative disease in a subject, treating a psychotropic disorder in a subject, or a combination thereof by administering to a subject a therapeutically effective amount of one or more of the compounds or compositions described herein, or a pharmaceutically acceptable salt thereof.

Abstract: A forecast-integrated automated control system for combined greywater-stormwater storage and reuse. A simple and reliable approach for managing greywater and stormwater collection at a household or community level is provided, allowing for the near-continuous monitoring and adjustment of water quantity and quality in a combined greywater-stormwater storage tank based on monitored feedback/output from individual, tank-specific sensors and/or sensors located elsewhere in the water collection system. Use of the forecast-integrated automated control system for combined greywater-stormwater storage and reuse enables optimization of the water quality and quantity collected in the storage tank, reduce the amount of stormwater discharged to municipal sewers, and assure/demonstrate regulatory compliance for control of stormwater runoff through the integration of a low impact development best management practices.

Abstract: Housingless positive displacement pump assembly comprises one or more vane or gerotor type housingless positive displacement pump units, each comprising pump unit components. One or more retaining rods extend through axially aligned holes in a mounting flange at one end of the pump assembly and the pump unit components to hold the pump unit components in stacked relation to one another and connect the pump assembly to the mounting flange.

Abstract: The invention relates to novel ligands of the estrogen receptors ? and ? of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions useful for hormone replacement therapy, as well as for the treatment of tumors and inflammatory diseases. The invention also relates to a novel preparation method of these ligands comprising cyclotrimerization of ethynylestradiol with the appropriate diyne in an organic solvent. Further, the invention relates to pharmaceuticals comprising the novel compounds according to the invention.

Abstract: Housingless positive displacement pump assembly comprises one or more vane or gerotor type housingless positive displacement pump units, each comprising pump unit components. One or more retaining rods extend through axially aligned holes in a mounting flange at one end of the pump assembly and the pump unit components to hold the pump unit components in stacked relation to one another and connect the pump assembly to the mounting flange.

Abstract: The invention relates to novel ligands of the estrogen receptors ? and ? of general formula II, which are useful as an active substance of pharmaceuticals, for example pharmaceutical compositions useful for hormone replacement therapy, as well as for the treatment of tumors and inflammatory diseases. The invention also relates to a novel preparation method of these ligands comprising cyclotrimerization of ethynylestradiol with the appropriate diyne in an organic solvent. Further, the invention relates to pharmaceuticals comprising the novel compounds according to the invention.

Abstract: A magneto-rheological clutch assembly for use in an electromechanical system. The clutch assembly includes a motor having a shaft that is coupled to a magneto-rheological clutch. There is also included a gear plate that is attached to the clutch, as well as being connected to a contact plate and pinion gear. The pinion gear engages a corresponding connection of a power operator system. The magneto-rheological clutch prevents damage to the motor power operator system and panel by simulating a slipping condition when a load exceeding a specified tolerance is applied to the panel.

Abstract: A passenger van is equipped with a drive mechanism for power operation of a slideable side door. The drive mechanism has a flexible drive cable that travels in a closed loop that includes cable portions that travel through a center track in opposite directions. The center track supports and guides a roller assembly that is attached to the rear of the side door. The roller assembly carries a cinch mechanism that selectively connects the roller assembly to a portion of the cable that is traveling in one direction to open the sliding door and that selectively connects the roller assembly to a portion of the cable that is traveling in the opposite direction to close the sliding door. The cinch mechanism is normally disconnected from the cable so that the side door can be opened or closed manually very easily.

Abstract: Apparatus for opening and closing a deck lid of a vehicle body. An elongated rack is mounted in a housing for longitudinal movement. A rotatable pinion meshes with the rack to move the rack longitudinally in one direction or the other depending on the direction of rotation of the pinion. A reversible motor rotates the pinion in opposite directions. The deck lid is attached to a pair of arms pivoted to the vehicle body. A link has one end pivoted to the rack and the opposite end pivoted to one of the arms. The deck lid is moved to open position in response to longitudinal movement of the rack in one direction or to closed position in response to longitudinal movement of the rack in the other direction.

Abstract: A latch handle assembly for permitting power or manual unlatching of a door latch. The assembly includes a latch handle for manual unlatching of the vehicle door. A mechanical linkage is attached to the latch handle and is adapted to interconnect with the door latch. The latch handle assembly also includes a switch disposed on the latch handle. The switch interconnects with a power-assisted unlatching mechanism that allows the switch to unlatch the door. Finally, there is a handle lock disposed adjacent the latch handle for disabling the latch handle in the normal condition when power is on and the power-assisted unlatching function is operable. The handle lock is operative to move from a locked position preventing the latch handle from moving, and an unlocked position allowing movement of the latch handle.

Abstract: A vehicle has a power operated liftgate and at least one power unit comprising a fixed linear guide channel and a follower that moves in the guide channel. The follower is universally connected to a rod having at one end and the opposite end of the rod is universally connected to the vehicle lift gate. A flexible drive loop which is attached to the follower wraps part way around two pulleys at opposite ends of the guide channel. The flexible drive loop is driven by a bi-directional drive unit that includes a reversible electric motor, an electromagnetic clutch and a drive wheel that engages the flexible drive loop. The flexible drive loop may be a drive cable, a drive tape, or a drive chain or a combination of cable, tape and/or chain.

Abstract: A power operating system for opening and closing a vehicle liftgate has a pair of drive units supported on the vehicle pillars at the sides of the liftgate opening. Each drive unit includes a vertically oriented channel and a rack bar that moves in the channel. A link is universally attached to the rack bar at one end and universally attached to the liftgate at the opposite end. The rack bar is raised and lowered by a power unit that has a motor driven pinion gear that meshes with the rack bar. Raising and lowering the rack bar opens and closes the liftgate via the link.

Abstract: A power operating system for opening and closing a vehicle liftgate has a pair of drive units supported on the vehicle pillars at the sides of the liftgate opening. Each drive unit includes a vertically oriented channel and a rack bar that moves in the channel. A link is universally attached to the rack bar at one end and universally attached to the liftgate at the opposite end. The rack bar is raised and lowered by a power unit that has a motor driven pinion gear that meshes with the rack bar. Raising and lowering the rack bar opens and closes the liftgate via the link.

Abstract: A power operating system opens and closes a vehicle liftgate that is pivotally attached to an aft end of a vehicle roof for pivotal movement between and open position and a closed position about a generally horizontal hinge axis. The power operating system has a gas spring strut counterbalance system and at least one drive unit that includes a reversible electric motor, a spool driven by the electric motor, a flexible web that has one end attached to the spool and an opposite end attached to the liftgate, and a pusher member that is driven by the electric motor between a retracted position and an extended position. The pusher member engages the liftgate and rotates the liftgate part way to the open position. The liftgate is closed by winding the flexible web onto the spool.

Abstract: A vehicle has a power operated liftgate and at least one power unit comprising a fixed linear guide channel and a follower that moves in the guide channel. The follower is universally connected to a rod having at one end and the opposite end of the rod is universally connected to the vehicle lift gate. A flexible drive loop which is attached to the follower wraps part way around two pulleys at opposite ends of the guide channel. The flexible drive loop is driven by a bi-directional drive unit that includes a reversible electric motor, an electromagnetic clutch and a drive wheel that engages the flexible drive loop. The flexible drive loop may be a drive cable, a drive tape, or a drive chain or a combination of cable, tape and/or chain.