Patents by Inventor David A. Selinger

David A. Selinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11242535
    Abstract: The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: February 8, 2022
    Inventors: Scott Diehn, Ajit Nott, David A Selinger, Carl Simmons, Priyanka Bhyri, Venkata S Tavva
  • Patent number: 10344290
    Abstract: The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
    Type: Grant
    Filed: July 26, 2017
    Date of Patent: July 9, 2019
    Assignees: E I DU PONT DE NEMOURS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Scott Diehen, Ajit Nott, David A. Selinger, Carl Simmons, Priyanka Bhyri, Venkata S. Tavva
  • Patent number: 8735652
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (USX) genes.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: May 27, 2014
    Assignee: Pioneer Hi-Bred International Inc
    Inventors: Xiaoming Bao, George W Singletary, Deborah J Wetterberg, Ramesh Nair, Kanwarpal S Dhugga, Matthias Liebergesell, David A Selinger
  • Publication number: 20130254932
    Abstract: The invention relates to gene expression regulatory sequences from maize, specifically to a promoter sequence and an intron sequence, that are useful for expressing transgenes in transgenic plants. The invention further discloses compositions, polynucleotide constructs, transformed host cells, transgenic plants and seeds containing the recombinant construct with the promoter and intron sequences, and methods for preparing and using the same.
    Type: Application
    Filed: December 21, 2011
    Publication date: September 26, 2013
    Applicant: E.I. DU PONT DE NUMOURS AND COMPANY
    Inventors: Ajit Nott, David A. Selinger, Venkata S. Tavva
  • Publication number: 20130145502
    Abstract: The invention relates to gene expression regulatory sequences, specifically introns that act as enhancers of gene expression, the promoter and terminator sequences endogenously associated with these introns. Presence of these intronic enhancer sequences in proximity to promoter sequences leads to enhancement of gene expression. Methods of finding such new intronic enhancer sequences and using them to generate transgenic plants are also described.
    Type: Application
    Filed: June 9, 2011
    Publication date: June 6, 2013
    Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANY
    Inventors: Scott Diehn, Ajit Nott, David A. Selinger, Carl R. Simmons, Priyanka Bhyri, Venkata S. Tavva
  • Publication number: 20130014290
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (USX) genes.
    Type: Application
    Filed: September 13, 2012
    Publication date: January 10, 2013
    Applicant: PIONEER HI BRED INTERNATIONAL, INC
    Inventors: Xiaoming Bao, George W. Singletary, Deborah J. Wetterberg, Ramesh Nair, Kanwarpal S. Dhugga, Matthias Liebergesell, David A. Selinger
  • Patent number: 8293973
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (UXS) genes.
    Type: Grant
    Filed: August 2, 2011
    Date of Patent: October 23, 2012
    Assignee: Pioneer Hi Bred International Inc
    Inventors: Xiaoming Bao, George W Singletary, Deborah J Wetterberg, Ramesh Nair, Kanwarpal S Dhugga, Matthias Liebergesell, David A Selinger
  • Patent number: 8173866
    Abstract: The present invention provides compositions and methods for manipulation of plant arabinoxylose and plant xylan synthases. Compositions include novel nucleotide sequences encoding xylan synthases and biologically active variants thereof. The invention also includes the discovery xylan synthase activity is a property of CslA polypeptides. Further provided are methods for xylose manipulation using the sequences disclosed herein. One method comprises stably incorporating into the genome of a plant cell, a CslA encoding nucleotide sequence operably linked to a heterologous promoter and regenerating a stably transformed plant. Methods for enhancing digestibility of plants and improving gum production in plants are also provided.
    Type: Grant
    Filed: January 12, 2009
    Date of Patent: May 8, 2012
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Xiaoming Bao, Kanwarpal S. Dhugga, Deborah J. Wetterberg, David A. Selinger, Rajeev Gupta
  • Publication number: 20120005780
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (UXS) genes.
    Type: Application
    Filed: August 2, 2011
    Publication date: January 5, 2012
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Xiaoming Bao, George W. Singletary, Deborah J. Wetterberg, Ramesh Nair, Kanwarpal S Dhugga, Matthias Liebergesell, David A. Selinger
  • Patent number: 8017831
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (UXS) genes.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: September 13, 2011
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Xiaoming Bao, George W. Singletary, Deborah J. Wetterberg, Ramesh Nair, Kanwarpal S. Dhugga, Matthias Liebergesell, David A. Selinger
  • Patent number: 7964770
    Abstract: The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the sorghum ?-kafirin coding region. The sequences drive expression preferentially to endosperm tissue. A method for expressing a nucleotide sequence in a plant using the regulatory sequences disclosed herein is provided. The method comprises transforming a plant cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed plant from the transformed plant cell.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: June 21, 2011
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Shane E. Abbitt, Rudolf Jung, David A. Selinger
  • Patent number: 7847160
    Abstract: The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the sorghum ?-kafirin coding region or from the sorghum ?-kafirin coding region. The sequences drive expression preferentially to endosperm tissue. A method for expressing a nucleotide sequence in a plant using the regulatory sequences disclosed herein is provided. The method comprises transforming a plant cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed plant from the transformed plant cell.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: December 7, 2010
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Shane E. Abbitt, Rudolf Jung, David A. Selinger
  • Publication number: 20090260105
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (UXS) genes.
    Type: Application
    Filed: June 18, 2009
    Publication date: October 15, 2009
    Applicant: Pioneer Hi-Bred International, Inc.
    Inventors: Xiaoming Bao, George W. Singletary, Deborah J. Wetterberg, Ramesh Nair, Kanwarpal S. Dhugga, Matthias Liebergesell, David A. Selinger
  • Patent number: 7592505
    Abstract: The present disclosure concerns methods and compositions relating to UXS polypeptides and/or nucleic acids encoding UXS polypeptides. In certain claims, the methods and compositions are of use to improve digestibility and/or ease of grain processing. Such improvements relate to a modulation in arabinoxylan and/or hemicellulose content in transgenic plants. Such plants can, for example, comprise one or more nucleic acid sequences that inhibit expression of one or more UDP-Xylose Synthase (UXS) genes.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: September 22, 2009
    Assignee: Pioneer Hi-Bred International, Inc.
    Inventors: Xiaoming Bao, George W. Singletary, Deborah J. Wetterberg, Ramesh Nair, Kanwarpal S. Dhugga, Matthias Liebergesell, David A. Selinger
  • Publication number: 20090188003
    Abstract: The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions comprise novel polypeptides involved in modulating gene expression in response to abiotic stress such as cold or drought, and the polynucleotides encoding the polypeptides. Methods for expressing the polynucleotides in a plant and improving cold and/or drought tolerance of plants are also provided.
    Type: Application
    Filed: January 23, 2009
    Publication date: July 23, 2009
    Applicant: PIONEER HI-BRED INTERNATIONAL, INC.
    Inventors: Shoba Sivasankar, David A. Selinger, Norbert Brugiere
  • Publication number: 20090089897
    Abstract: The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the sorghum ?-kafirin coding region. The sequences drive expression preferentially to endosperm tissue. A method for expressing a nucleotide sequence in a plant using the regulatory sequences disclosed herein is provided. The method comprises transforming a plant cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed plant from the transformed plant cell.
    Type: Application
    Filed: September 24, 2008
    Publication date: April 2, 2009
    Inventors: Shane E. Abbitt, Rudolf Jung, David A. Selinger
  • Publication number: 20090049571
    Abstract: The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions are novel nucleotide sequences for a tissue preferred promoter isolated from the sorghum ?-kafirin coding region or from the sorghum ?-kafirin coding region. The sequences drive expression preferentially to endosperm tissue. A method for expressing a nucleotide sequence in a plant using the regulatory sequences disclosed herein is provided. The method comprises transforming a plant cell to comprise a nucleotide sequence operably linked to one or more of the regulatory sequences of the present invention and regenerating a stably transformed plant from the transformed plant cell.
    Type: Application
    Filed: June 25, 2008
    Publication date: February 19, 2009
    Inventors: Shane E. Abbitt, Rudolf Jung, David A. Selinger