Patents by Inventor David A. Spiegel

David A. Spiegel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20110201563
    Abstract: The present invention relates to chimeric chemical compounds which are used to recruit antibodies to cancer cells, in particular, prostate cancer cells or metastasized prostate cancer cells. The compounds according to the present invention comprise an antibody binding terminus (ABT) moiety covalently bonded to a cell binding terminus (CBT) through a linker and optionally, a connector molecule.
    Type: Application
    Filed: May 13, 2009
    Publication date: August 18, 2011
    Applicant: YALE UNIVERSITY
    Inventors: David Spiegel, Ryan Murelli, Andrew Zhang
  • Patent number: 4237425
    Abstract: A bias adjusting circuit for a push-pull amplifier is disclosed, which automatically increases or decreases the bias in the amplifier circuit so that the desired bias level is maintained. The bias adjusting circuit measures the current consumption of both halves of the push-pull amplifier, determines the point at which output current zero crossings have occurred, and at these times makes any necessary changes to the bias current to conform to a desired level. The circuit has an insignificant effect on the amplifier's power efficiency, and offers a degree of bias stability unattainable with conventional techniques.
    Type: Grant
    Filed: May 3, 1979
    Date of Patent: December 2, 1980
    Inventor: David A. Spiegel