Patents by Inventor David A. Usher

David A. Usher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protected nucleoside and method for its synthesis
    Patent number: 5808035
    Abstract: The present invention relates to a nucleoside having the formula: ##STR1## where R.sub.1 is a hydrogen or a protecting group;R.sub.2 is a hydrogen or a coupling group;R.sub.3 and R.sub.4 are each either a hydrogen or an alkyl group, where R.sub.3 and R.sub.4 can be connected in a ring;R.sub.5 is a hydrogen, an alkyl group, or a carboxylic ester group;R.sub.6 is a hydrogen, an alkyl group, or a carboxylic ester group;R.sub.7 is a hydrogen, a nitro group, a halogen, a cyano group, or an alkyl group, where R.sub.7 is attached at either position 4, 5 or 6; andBase is a protected heterocyclic base. Further, the present invention relates to a method of making the nucleoside and a method of oligomer synthesis utilizing the nucleoside.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: September 15, 1998
    Inventors: David A. Usher, Himanshu Rastogi
  • Nucleic acid analog with amide linkage and method of making that analog
    Patent number: 5637683
    Abstract: The present invention relates to a nucleic acid analog having the formula: ##STR1## where R is a compound selected from a group consisting of hydrogen, a hydroxyl group, a hydrophilic group or a hydrophobic group,n is greater than or equal to 2, andBase is uracil, adenine, guanine, cytosine, thymine or hypoxanthine, with Bases in the analog being the same or different. Further, the present invention relates to a processes for making and using the analog.
    Type: Grant
    Filed: July 13, 1995
    Date of Patent: June 10, 1997
    Assignee: Cornell Research Foundation, Inc.
    Inventors: David A. Usher, Mark F. Harris, Clarence J. Wang