Patents by Inventor David A. Wade

David A. Wade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7351535
    Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.
    Type: Grant
    Filed: August 18, 2004
    Date of Patent: April 1, 2008
    Assignee: CV Therapeutics, Inc.
    Inventors: Richard M Lawn, David Wade, Michael Garvin
  • Publication number: 20050214793
    Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.
    Type: Application
    Filed: October 25, 2004
    Publication date: September 29, 2005
    Applicants: CV Therapeutics, Inc., University of Washington
    Inventors: Richard Lawn, David Wade, Michael Garvin, John Oram
  • Publication number: 20050178928
    Abstract: A multi-use wayside railway control system for installation and use in operating wayside railway equipment in a railway wayside application selected from among a plurality of differing railway wayside applications in which the control system could be used. The system includes detectors responsive to and generating data indicative of operating conditions of the selected wayside application, with the data being transmitted to a controller. The controller receives data from the detectors and is responsive to the data for operating the wayside equipment. A programmed processor is operatively associated with the controller and includes a software program storage device for storing a plurality of separately selectable operating programs, each of the operating programs comprising application specific information for a selected wayside application and corresponding configuration of wayside equipment.
    Type: Application
    Filed: January 20, 2005
    Publication date: August 18, 2005
    Inventors: David Wade, Shawn Clark, Steve Murphy
  • Publication number: 20050009089
    Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.
    Type: Application
    Filed: August 18, 2004
    Publication date: January 13, 2005
    Applicant: CV Therapeutics, Inc.
    Inventors: Richard Lawn, David Wade, Michael Garvin
  • Patent number: 6835563
    Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: December 28, 2004
    Assignee: CV Therapeutics
    Inventors: Richard M. Lawn, David Wade, Michael Garvin, John F. Oram
  • Patent number: 6821774
    Abstract: The present invention relates to novel ABC1 polypeptides and nucleic acid molecules encoding the same. The invention also relates to recombinant vectors, host cells, and compositions comprising ABC1 polynucleotides, as well as to methods for producing ABC1 polypeptides. The invention also relates to antibodies that bind specifically to ABC1 polypeptides. In addition, the invention relates to methods for increasing cholesterol efflux as well as to methods for increasing ABC1 expression and activity. The present invention further relates to methods for identifying compounds that modulate the expression of ABC1 and methods for detecting the comparative level of ABC1 polypeptides and polynucleotides in a mammalian subject. The present invention also provides kits and compositions suitable for screening compounds to determine the ABC1 expression modulating activity of the compound, as well as kits and compositions suitable to determine whether a compound modulates ABC1-dependent cholesterol efflux.
    Type: Grant
    Filed: June 16, 2000
    Date of Patent: November 23, 2004
    Assignee: CV Therapeutics, Inc.
    Inventors: Richard M. Lawn, David Wade, Michael Garvin
  • Patent number: 5967469
    Abstract: A foldable sandbag holder for supporting a conventional sandbag in an upright open-mouthed position, comprising a rear frame member having two rear vertical rods which are braced by means of crossbars extending therebetween, and a pair of side members, each side member having a front vertical rod. The side members are pivotally connected to the rear vertical rods and are movable between a flat configuration wherein the side members are folded against the rear frame member and an open rectangular configuration wherein the side members are positioned generally transversely with respect to the rear frame member. The front and rear vertical rods have pointed upper ends for piercing through the peripheral end portion of a sandbag to maintain the bag in an upright position with the mouth thereof spread open, so that it can be easily filled with sand. The vertical rods also have pointed lower ends for penetrating the ground to provide stability during filling operation.
    Type: Grant
    Filed: August 20, 1998
    Date of Patent: October 19, 1999
    Inventor: David Wade
  • Patent number: 5913365
    Abstract: A method for removing a gravel-pack screen from a wellbore. of a well which has been "gravel packed". When it is desired to remove the screen from the wellbore, a washstring is lowered down the wellbore and into the interior of said screen. A wash fluid is then flowed fluid down the washstring and out through said screen into said mass of gravel surrounding the screen to fluidize, loosen, and remove said gravel. Once the mass of gravel has been loosen, the screen can then lifted upward out of said wellbore by applying a normal upward force the workstring which suspends the screen within the well.
    Type: Grant
    Filed: April 8, 1997
    Date of Patent: June 22, 1999
    Assignee: Mobil Oil Corporation
    Inventor: David Wade Bryant
  • Patent number: 5868200
    Abstract: An alternate-path, well screen made-up of joints and having a sleeve positioned between the ends of adjacent joints which acts as a manifold for fluidly-connecting the alternate-paths on one joint with the alternate-paths on an adjacent joint.
    Type: Grant
    Filed: April 17, 1997
    Date of Patent: February 9, 1999
    Assignee: Mobil Oil Corporation
    Inventors: David Wade Bryant, George A. Gillespie, Steven J. Tupy
  • Patent number: 5585353
    Abstract: Antibiotically and/or antimalarially active D-peptides of naturally occurring antibiotics such as cecropin A, B and D, melittin, and Magainin I and II and their addition, deletion and replacement analogs including homologous and heterologous analogs thereof.
    Type: Grant
    Filed: September 16, 1994
    Date of Patent: December 17, 1996
    Assignee: The Rockefeller University
    Inventors: Robert B. Merrifield, David Wade, Hans G. Boman
  • Patent number: 4706818
    Abstract: A device for preventing magnetically attractable flatware and other objects from falling into a food disposer. Round tubes containing magnets are arranged parallel to one another across a collar at the mouth of the disposer. Each tube contains an assembly of cylindrical magnets, separated by spacers, which are magnetized and oriented to provide a strong attractive force around the tube.
    Type: Grant
    Filed: May 16, 1986
    Date of Patent: November 17, 1987
    Inventors: Stephen W. Zutell, David A. Wade, James V. Hanson