Patents by Inventor David A. Walters

David A. Walters has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10577669
    Abstract: Gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme. A method for treating one or more than one inflammation-related condition or disease, the method comprising administering gene-modified, lymphoid-tissue-homing dendritic cells that comprise a 1-alpha-hydroxylase gene and a retinaldehyde dehydrogenase 2 gene, where the 1-alpha-hydroxylase gene is expressed to produce functional 1-alpha-hydroxylase enzyme and the retinaldehyde dehydrogenase 2 gene is expressed to produce functional retinaldehyde dehydrogenase 2 gene enzyme.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: March 3, 2020
    Assignee: Loma Linda University
    Inventors: Xiaolei Tang, David J. Baylink, K.-H. William Lau, Michael Walter
  • Patent number: 10578476
    Abstract: A three dimensional (3D) printing system includes an ink cartridge providing ink to a printhead and a controller. The ink cartridge also includes a flag material and a sensor component. The ink has a low dielectric constant and defines an upper surface having a vertical position defining an ink level. The flag material has a high dielectric constant and is disposed upon the upper surface of the ink. The sensor component includes a vertical arrangement of electrodes proximate to the ink. The controller is coupled to the sensor electrodes and is configured to: (1) scan sensor electrodes to determine a capacitance between adjacent pairs of electrodes, (2) identify at least one pair of electrodes having a peak capacitance value relative to capacitance values of remaining pairs of electrodes, and (3) estimate the ink level based upon the identification.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: March 3, 2020
    Assignee: 3D Systems, Inc.
    Inventor: David Walter Johnson
  • Publication number: 20200055611
    Abstract: An isolator fitting for an opening in a metallic rib of an aircraft wing. The isolator fitting has first isolator mountable to the rib to position a first isolator opening in alignment with the opening of the rib. A second isolator is mountable to the rib and has a nut housing segment defining a second isolator opening to be positioned in alignment with the opening of the rib. A conduit extends between a first end and a second end, and a nut is mountable about an outer surface of the conduit to abut against the first isolator and mount the conduit thereto. The conduit is positionable to extend through the opening of the rib and through the first and second isolator openings to position the nut within the nut housing segment of the second isolator such that the nut housing segment is positioned between the nut and the rib.
    Type: Application
    Filed: August 6, 2019
    Publication date: February 20, 2020
    Inventors: Stephen WALTERS, David CHIVERS
  • Patent number: 10567746
    Abstract: A calibration jig for calibrating an image capturing device mounted on a machine is provided. A second rope is connected to a first rope at a first connection point. A third rope is connected to the first rope and the second rope at a second connection point and a third connection point respectively. The first, second, and third ropes, when taut, define the calibration triangle with the first, second, and the third connection points as vertices of the calibration triangle. A center rope is connected to the first connection point with a first anchor point associated with the machine. A first tether rope is connected to the second connection point of the calibration triangle with a second anchor point associated with the machine. A second tether rope is connected to the third connection point of the calibration triangle with a third anchor point associated with the machine.
    Type: Grant
    Filed: November 14, 2017
    Date of Patent: February 18, 2020
    Assignee: Caterpillar Inc.
    Inventors: Paul Russell Friend, David Paul Gitz, Maikel Orlando Torres Pineiro, Matthew Daniel Fike, Qi Chen, Jeffrey Walter Earleson
  • Publication number: 20200040819
    Abstract: An air inlet system for an auxiliary power unit (APU) has an intake duct having a wall defining an inlet plenum and forming an inlet opening configured to direct air into the inlet plenum. The system further comprising a load compressor passage in fluid communication with the inlet plenum and leading to a load compressor of the APU; and a core compressor passage in fluid communication with the inlet plenum and leading to a core compressor of the APU. A deflector is provided in the inlet plenum between the inlet opening and the core compressor inlet to deflect at least part of particles carried by an incoming airflow away from the core compressor inlet toward the load compressor inlet.
    Type: Application
    Filed: August 3, 2018
    Publication date: February 6, 2020
    Inventors: Nigel WALTERS, Nicholas NGOLY, David CERANTOLA, Mark CUNNINGHAM, Roger LACHANCE
  • Publication number: 20200036273
    Abstract: A linear electromagnetic machine includes a stator, a translator, and a bearing system. The bearing system maintains alignment against lateral displacement of the translator relative to the stator, as the translator reciprocates axially. More particularly, the bearing system maintains a motor air gap between the stator and a magnetic section of the translator. The stator includes a plurality of stator teeth and windings, which form a plurality of phases. The stator teeth and windings are arranged using a hoop stack with spines to form a stator bore and define the motor air gap. The bearing system can include bearing housings that are configured to form a bearing interface with a surface of the translator. The bearing interface can include a contact bearing or a non-contact bearing, such as a gas bearing. Current is controlled in the phases to convert between electrical energy and kinetic energy of the translator.
    Type: Application
    Filed: July 24, 2019
    Publication date: January 30, 2020
    Inventors: John Lawler, John Powers, Scott Coakley, Alan Crapo, David DeGraaff, Christopher David Gadda, Andrew Hancock, Shannon Miller, Samuel Sherman, Matthew Svrcek, Kevin Walters
  • Patent number: 10547143
    Abstract: A wiring-harness includes an electrical-connector and a staging-device. The staging-device has a cavity defining a flexible-member in compressive contact with the electrical-connector. The flexible-member is configured to removably retain the electrical-connector within the cavity. The cavity locates the electrical-connector in a predetermined-position within the staging-device, such that the electrical-connector is presented to an assembler in the predetermined-position. The staging-device is particularly useful in automated, i.e. robotic, installation of the wiring-harness.
    Type: Grant
    Filed: May 31, 2019
    Date of Patent: January 28, 2020
    Assignee: APTIV TECHNOLOGIES LIMITED
    Inventors: David R. Peterson, Joseph Sudik, Jr., Frank Walter Szuba, Jr., Mark Intihar, Benjamin Decker, Andrew Kneppers
  • Publication number: 20200026254
    Abstract: In order to enable a seamless configuration modification during operation, a first automation device sends a second automation device a request for parameter modification. The second automation device responds to the request, such that a standby acknowledgement of the request is sent. Immediately with the transmission of the standby acknowledgement in the second automation device, an output process image is frozen, and the modification of the communication parameters for the second automation device is carried out. The first automation device responds, such that after receiving the standby acknowledgement in the first automation device, the communication is immediately stopped and the modification of the communication parameters is carried out for the first automation device. An input process image is frozen.
    Type: Application
    Filed: July 16, 2019
    Publication date: January 23, 2020
    Inventors: Herbert Barthel, David Ferenczi, Wolfgang Schmauss, Maximilian Walter
  • Publication number: 20200017512
    Abstract: The present invention relates to methods of using compounds of Formula I, wherein R1a, R1b, R2, R3, R4, W, Y, and Z are as described herein, and pharmaceutically acceptable salts thereof. The compounds are potentiators of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). The invention also discloses pharmaceutical compositions comprising the compound, optionally in combination with additional therapeutic agents, and methods of potentiating, in mammals, including humans, CFTR by administration of the compounds. These compounds are useful for the treatment of cystic fibrosis (CF), asthma, bronchiectasis, chronic obstructive pulmonary disease (COPD), constipation, Diabetes mellitus, dry eye disease, pancreatitis, rhinosinusitis, Sjögren's Syndrome, and other CFTR associated disorders.
    Type: Application
    Filed: September 20, 2019
    Publication date: January 16, 2020
    Inventors: Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, Atli Thorarensen, Rajiah Aldrin Denny, Christoph Wolfgang Zapf, Daniel Elbaum, Lori Krim Gavrin, Ivan Viktorovich Efremov
  • Publication number: 20200008957
    Abstract: A trial medical instrument for aligning an acetabular component, comprising: a first portion configured to fit within a patient's acetabulum; and a second portion extending from the first portion; wherein the second portion extends from the first portion in a direction that mimics a shape formed by a femoral implant component coupled with an acetabular implant component when a femur to which the femoral implant component is coupled is in a position relative to an acetabulum to which the acetabular implant component is coupled that is near an extent of a typical range of motion of the femur. As used herein, the phrase “extent of a typical range of motion” describes typical angular displacements of a femur as usually limited by patient anatomy.
    Type: Application
    Filed: September 19, 2019
    Publication date: January 9, 2020
    Inventors: David C. Kelman, John Clausen, M. Scott Elliot, David L. Evans, Kevin W. Belew, David W. Rister, Phillip E. Fredrick, Russell Walter
  • Publication number: 20200000302
    Abstract: A mobile cleaning robot system can include a mobile clearing robot and a vacuum system. The mobile cleaning robot can include a support structure and a drive system operative to move the mobile cleaning robot. The vacuum system can be configured to vacuum a surface.
    Type: Application
    Filed: June 27, 2019
    Publication date: January 2, 2020
    Inventors: Russell Walter Morin, Eric J. Burbank, Erik Amaral, Rogelio Manfred Neumann, David O. Swett
  • Patent number: 10518830
    Abstract: A climbing vehicle with wheel or endless-track type propulsion using suction for generating adhering forces is adapted to climbing non-planar surfaces such as intersecting walls, pipes or other structural members. The suction chamber is relatively fixed to the vehicle chassis and moves with the vehicle chassis. A seal is created around the suction chamber through an adaptive sealing mechanism. The adaptive sealing mechanism consists of a series of links that adapt to the climbing surface geometry and forms a seal at the climbing surface. The links in the adaptive sealing mechanism span a portion of the suction chamber along the longitudinal sides of the vehicle and are elastically sprung to maintain contact with the surface. The adaptive sealing mechanism links also span the lateral sides of the vehicle to fully enclose the suction chamber.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: December 31, 2019
    Inventors: James Walter Beard, III, Stephen Lee Canfield, David Andrew Bryant, Steve Glovsky
  • Publication number: 20190389412
    Abstract: A trim component, such as a grill of a vehicle, includes a substrate having a 3-dimensional shape and defining a disrupted reflective surface including a plurality of facets over a curved surface. Each of the facets is configured to reflect an incident light beam in a common direction, for example, toward a given target. A reflective coating, such as a chrome plating layer, overlies the disrupted reflective surface. The facets may have similar shapes and/or be arranged in a repeating pattern, but with one or more irregular features. The sizes, shapes, and/or orientation direction of the facets may varying in a gradient based on the curvature of the curved surface. The trim component also includes a light source to illuminate the disrupted reflective surface. The light source may be hidden so it is not directly visible to a viewer, but instead is reflected by the disrupted reflective surface.
    Type: Application
    Filed: June 25, 2019
    Publication date: December 26, 2019
    Inventors: David WALTERS, Thomas HAWKINS
  • Publication number: 20190390696
    Abstract: A connector for interlocking components of scaffolding or other supporting structures for building forms. The connector includes a body having an internal chamber bounded laterally by planar first and second surfaces. A lever is seated in the chamber laterally intermediate and in close fit with the planar first and second surfaces for inhibiting lateral movement of the lever. The lever is movable between a lock position and a release position. A spring is seated in the chamber laterally intermediate and in close fit with the planar first and second surfaces for inhibiting lateral movement of the spring, the spring for biasing the lever into the lock position.
    Type: Application
    Filed: June 26, 2019
    Publication date: December 26, 2019
    Inventors: David George Jackson, Barry Walter Jackson
  • Publication number: 20190393469
    Abstract: The discharge performance of a primary, bobbin-style electrochemical cell is improved by incorporating a separator formed from a continuous separator sheet defining a two-layer cylindrical sidewall and a closed bottom end between the included electrochemical cell cathode and anode. A first layer of the cylindrical separator is formed by rolling a first end of a continuous separator sheet into a cylinder having a central axis parallel with a longitudinal axis of the continuous separator sheet, and then rolling a second end of the continuous separator sheet around the exterior of the first cylindrical layer to form a second cylindrical layer. The closed bottom end is formed by a portion of the continuous separator sheet located between the rolled portion of the first end and the rolled portion of the second end.
    Type: Application
    Filed: June 12, 2019
    Publication date: December 26, 2019
    Inventors: David Walter Kalisz, Maria G. Verikakis, Christopher S. Bolyos
  • Patent number: 10508392
    Abstract: A bridge overhang bracket assembly includes a top member, a diagonal member and a side member. The top and diagonal members are pivotally attached proximate to respective outer and upper ends thereof. The top and side members are pivotally attached proximate to respective inner and top ends thereof. The diagonal and side members are pivotally attached proximate to respective lower and bottom ends thereof. The side member is configured so that its length between the bottom and top ends is adjustable.
    Type: Grant
    Filed: January 18, 2019
    Date of Patent: December 17, 2019
    Inventors: Barry Walter Jackson, David George Jackson, Scott Fisk
  • Patent number: 10494374
    Abstract: The present invention relates to methods of using compounds of Formula I, wherein R1a, R1b, R2, R3, R4, W, Y, and Z are as described herein, and pharmaceutically acceptable salts thereof. The compounds are potentiators of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). The invention also discloses pharmaceutical compositions comprising the compound, optionally in combination with additional therapeutic agents, and methods of potentiating, in mammals, including humans, CFTR by administration of the compounds. These compounds are useful for the treatment of cystic fibrosis (CF), asthma, bronchiectasis, chronic obstructive pulmonary disease (COPD), constipation, Diabetes mellitus, dry eye disease, pancreatitis, rhinosinusitis, Sjögren's Syndrome, and other CFTR associated disorders.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: December 3, 2019
    Assignee: CYSTIC FIBROSIS FOUNDATION
    Inventors: Joseph Walter Strohbach, David Christopher Limburg, John Paul Mathias, Atli Thorarensen, Rajiah Aldrin Denny, Christoph Wolfgang Zapf, Daniel Elbaum, Lori Krim Gavrin, Ivan Viktorovich Efremov
  • Publication number: 20190362442
    Abstract: A method includes obtaining an identifier of an individual. The individual is associated with an entity such that the individual has an email address in a domain corresponding to the entity. The method also includes determining one or more candidate domains such that: the one or more candidate domains potentially correspond to the entity; and the individual potentially has the email address in at least one of the one or more candidate domains. The method further includes determining one or more candidate email addresses in at least one of the one or more candidate domains. The method additionally includes testing the one or more candidate email addresses and the one or more candidate domains to determine the email address of the individual in the domain corresponding to the entity.
    Type: Application
    Filed: August 7, 2019
    Publication date: November 28, 2019
    Applicant: Shocase, Inc.
    Inventors: Ronald P. Young, Peter Rugg, David Anthony Burgess, Joao Paulo Aumond, Robert Walter Kerns
  • Patent number: 10485442
    Abstract: An example of a system may include a sensing circuit to sense a cardiac signal indicative of atrial and ventricular depolarizations and an atrial fibrillation (AF) detection circuit to detect AF. The AF detection circuit may include a detector and a detection enhancer. The detector may be configured to detect the ventricular depolarizations using the cardiac signal, measure ventricular intervals, and detect AF using the ventricular intervals. The detection enhancer may be configured to generate atrial detection windows each being a time interval prior to each of the detected ventricular depolarizations, compute an atrial activity score using a rolling average of portions of the cardiac signal within the atrial detection windows, and verify the detection of the AF using the atrial activity score and an atrial activity threshold. The atrial activity score is a measure of consistency between a relationship between the atrial depolarizations and the ventricular depolarizations.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: November 26, 2019
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Jonathan Walter Krueger, Deepa Mahajan, David L. Perschbacher
  • Publication number: 20190345507
    Abstract: The invention provides methods and compositions for identifying transgenic seed that contain a transgene of interest, but lack a marker gene. Use of an identification sequence that results in a detectable phenotype increases the efficiency of screening for seed and plants in which transgene sequences not linked to a gene of interest have segregated from the sequence encoding a gene of interest.
    Type: Application
    Filed: March 20, 2019
    Publication date: November 14, 2019
    Inventors: Xudong Ye, Larry A. Gilbertson, Shihshieh Huang, Susan J. Johnson, Michael W. Petersen, David Walters, Paul S. Chomet