Abstract: A machine for rotary driving screw anchors into underlying ground and related. The machine has a mast with a rotary driver and a mandrel driver oriented on a common axis. The mandrel driver passes a mandrel through the rotary driver and the screw anchor to allow the mandrel to be actuated ahead of the screw anchor while the rotary driver drives the screw anchor into the ground. Alternatively, the mandrel driver may also drive a hammering drill through the screw anchor to clear a path ahead of it through subsurface rocks.

Abstract: The present disclosure provides methods and systems for processing or treating wastewater. The methods of systems of the present disclosure may perform a treatment process on a wastewater stream including gray water and black water to produce a product stream. The product stream may comprise a potable water stream or a stream of treated water with a reduced concentration of one or more contaminant originally included in the wastewater stream.

Abstract: A foundation system for manufactured homes, prefabricated houses, and other structures. Multiple screw anchors are driven into the ground at the desired location of the structure. Preformed grade bars may be placed over the screw anchors to provide a modular foundation without pouring concrete or digging footers.

Abstract: A method of generating a building assembly that includes spraying a coating material onto a plurality of pieces of substrate disposed on a first assembly face. The spraying includes spraying the coating material onto the plurality of pieces of substrate via a sprayer configured to apply the coating material to a target surface via a nozzle coupled with a mobile storage container storing the coating material, the coating material impregnating voids of the substrate. The method also includes allowing the coating material impregnating the voids to dry and harden and become rigid to generate the building assembly.

Abstract: A coating system for applying a coating to a substrate that can be part of a wall assembly. The system includes a positioning stage and an end effector coupled at a distal end of the positioning stage, the end effector configured to apply coating to a target surface. The system can further include a computing device executing a computational planner that: generates instructions for driving the end effector and positioning stage to perform at least one coating task that includes applying coating, via the coating the end effector, to one or more substrate pieces, the generating based at least in part on obtained target surface data; and drives the end effector and positioning stage to perform the at least one coating task.

Abstract: A machine for rotary driving screw anchors into underlying ground and related. The machine has a mast with a rotary driver and a mandrel driver oriented on a common axis. The mandrel driver passes a mandrel through the rotary driver and the screw anchor to allow the mandrel to be actuated ahead of the screw anchor while the rotary driver drives the screw anchor into the ground. Alternatively, the mandrel driver may also drive a hammering drill through the screw anchor to clear a path ahead of it through subsurface rocks.

Abstract: A coating system for applying a coating to a substrate that can be part of a wall assembly. The system includes a positioning stage and an end effector coupled at a distal end of the positioning stage, the end effector configured to apply coating to a target surface. The system can further include a computing device executing a computational planner that: generates instructions for driving the end effector and positioning stage to perform at least one coating task that includes applying coating, via the coating the end effector, to one or more substrate pieces, the generating based at least in part on obtained target surface data; and drives the end effector and positioning stage to perform the at least one coating task.

Abstract: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators may include a housing having a distal end and a proximal end, a cutting blade positioned at the distal end of the housing and a tissue actuator configured to be displaced along a longitudinal axis within the housing. Also provided are methods of using the tissue dissociators, as well as kits including the tissue dissociators.

Abstract: Methods and devices for exchanging therapeutic agents, such as cells, from one liquid medium to another liquid medium are provided. Aspects of embodiments of the methods include transferring a therapeutic agent from a first medium, such as a freezing, storage or shipping buffer, into a second medium, such as a sterile physiologically compatible buffer. In certain aspects, the transfer of the therapeutic agent from a first medium to a second medium involves the use of acoustic-focusing, or acoustophoresis. Embodiments of the subject methods may facilitate the transfer of a therapeutic agent from a storage medium to an infusion medium, and in certain embodiments include administering the therapeutic agent contained in the infusion medium to the subject. Also provided by the present disclosure are devices for practicing the subject methods.

Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.

Abstract: Methods and devices for exchanging therapeutic agents, such as cells, from one liquid medium to another liquid medium are provided. Aspects of embodiments of the methods include transferring a therapeutic agent from a first medium, such as a freezing, storage or shipping buffer, into a second medium, such as a sterile physiologically compatible buffer. In certain aspects, the transfer of the therapeutic agent from a first medium to a second medium involves the use of acoustic-focusing, or acoustophoresis. Embodiments of the subject methods may facilitate the transfer of a therapeutic agent from a storage medium to an infusion medium, and in certain embodiments include administering the therapeutic agent contained in the infusion medium to the subject. Also provided by the present disclosure are devices for practicing the subject methods.

Abstract: Systems for sterile separation of magnetically labeled sample components and methods for using the same are provided. Embodiments of the systems include a magnetic separation device and a pliant sample container, where a portion of the pliant sample container is operatively coupled under pressure to the magnetic separation device. Also provided are methods of using the systems, as well as pliant sample containers configured for use with the subject systems and methods.

Abstract: Methods and devices for exchanging therapeutic agents, such as cells, from one liquid medium to another liquid medium are provided. Aspects of embodiments of the methods include transferring a therapeutic agent from a first medium, such as a freezing, storage or shipping buffer, into a second medium, such as a sterile physiologically compatible buffer. In certain aspects, the transfer of the therapeutic agent from a first medium to a second medium involves the use of acoustic-focusing, or acoustophoresis. Embodiments of the subject methods may facilitate the transfer of a therapeutic agent from a storage medium to an infusion medium, and in certain embodiments include administering the therapeutic agent contained in the infusion medium to the subject. Also provided by the present disclosure are devices for practicing the subject methods.

Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.

Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.

Abstract: Methods and devices for exchanging therapeutic agents, such as cells, from one liquid medium to another liquid medium are provided. Aspects of embodiments of the methods include transferring a therapeutic agent from a first medium, such as a freezing, storage or shipping buffer, into a second medium, such as a sterile physiologically compatible buffer. In certain aspects, the transfer of the therapeutic agent from a first medium to a second medium involves the use of acoustic-focusing, or acoustophoresis. Embodiments of the subject methods may facilitate the transfer of a therapeutic agent from a storage medium to an infusion medium, and in certain embodiments include administering the therapeutic agent contained in the infusion medium to the subject. Also provided by the present disclosure are devices for practicing the subject methods.

Abstract: Tissue dissociators configured to disrupt a biological tissue sample are provided. Aspects of the tissue dissociators may include a housing having a distal end and a proximal end, a cutting blade positioned at the distal end of the housing and a tissue actuator configured to be displaced along a longitudinal axis within the housing. Also provided are methods of using the tissue dissociators, as well as kits including the tissue dissociators.

Abstract: Methods and devices for exchanging therapeutic agents, such as cells, from one liquid medium to another liquid medium are provided. Aspects of embodiments of the methods include transferring a therapeutic agent from a first medium, such as a freezing, storage or shipping buffer, into a second medium, such as a sterile physiologically compatible buffer. In certain aspects, the transfer of the therapeutic agent from a first medium to a second medium involves the use of acoustic-focusing, or acoustophoresis. Embodiments of the subject methods may facilitate the transfer of a therapeutic agent from a storage medium to an infusion medium, and in certain embodiments include administering the therapeutic agent contained in the infusion medium to the subject. Also provided by the present disclosure are devices for practicing the subject methods.

Abstract: Aspects of the present disclosure include methods for processing a biological sample. Methods according to certain embodiments include disrupting a biological sample to produce a disrupted biological sample and acoustically separating larger components from smaller components in the disrupted biological sample. In certain embodiments, methods may include monitoring aggregation while the biological sample is being processed. Methods, in certain instances, also include acoustically separating cells from cellular debris and non-cellular macromolecules as well as magnetically separating magnetically labelled moieties from unlabeled moieties. Systems, including a disrupter, one or more acoustic concentrator devices, feedback monitors and magnetic separation devices suitable for practicing the subject methods are also described.

Abstract: Devices for sorting components (e.g., cells) contained in a liquid sample are provided. In certain aspects, the devices include a magnetic separation device and an acoustic concentrator device fluidically coupled to magnetic separation device. Aspects of the invention further include methods for sorting cells in a liquid sample, and systems, and kits for practicing the subject methods.