Abstract: The present disclosure provides catanionic surfactant vesicles (SVs). The vesicles may be functionalized on their outer leaflet such that they may be biologically active. The vesicles may encapsulate (at least partially in the lumen and/or at least partially in the leaflet) one or more small molecules, one or more RNAs, one or more DNAs, and/or one or more proteins/peptides. Also provided are compositions comprising the vesicles (e.g., vaccine compositions comprising the vesicles) and methods of making and using the same.

Abstract: The present invention relates to methods of treatment of a disease or pathology of the central nervous system, an eating disorder, or substance use disorder, drug dependence/abuse/addiction and withdrawal therefrom comprising administering at least one N-phenylalkyl amphetamine derivative and pharmaceutical compositions comprising at least one N-phenylalkyl amphetamine derivative to an individual in need thereof.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to identify user presence to a meter. An example apparatus includes memory, instructions, and at least one hardware processor to execute the instructions to at least: obtain presence information from a configuration device, the configuration device separate from the apparatus, the presence information indicating that user is present at the apparatus; verify the presence information matches user information, the user information stored in a memory of the apparatus; cause a confirmation prompt to be displayed on the configuration device, the confirmation prompt to indicate the presence information was obtained by the apparatus; and store the presence information in memory.

Abstract: Provided are androstane and dihydrotestosterone compounds functionalized with carbocyclic groups or heterocyclic groups that may be saturated or unsaturated. The compounds may be used in methods of inhibiting cell growth of malignant cells and/or hyperplastic cells and/or treating individuals having diseases associated with malignant cell growth (e.g., cancer, such as, for example, prostate cancer) and/or hyperplastic cell growth and/or molecular imaging of malignant cells and/or hyperplastic cells and/or inducing degradation of a target protein. Also provided are compositions.

Abstract: Implementation of radio frequency applications in satellite environments can be constrained by size, mass, cost, and power limitations. These applications can include radar, communications, radio astronomy, or other scientific or industrial applications. A variety of systems are provided to facilitate recording of baseband radio frequency signals at high bandwidth and low power using low-cost components. These systems include field-programmable gate arrays or other programmable logic devices integrating between high-frequency ADCs and two or more multiplexed non-volatile storage mediums. Also provided are systems for providing calibration and self-test functionality in a low-cost, flexible, low-power radio frequency frontend. These systems include high-frequency switches configured to allow a calibration and/or self-test pulse to be acquired for each radar pulse generated by the system.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to identify user presence to a meter. An example apparatus includes a user input receiver to obtain presence information from a panelist via a prompt displayed by a user interface of the apparatus, the presence information indicating that the panelist is present at the meter separate from the apparatus, a configuration controller to package the presence information and insert an indication in the packaged presence information, the indication indicating the packaged information is to be sent to the meter via a remote server, and a wireless transceiver to transmit the packaged presence information to the remote server.

Abstract: A method, comprising: obtaining one or more accelerometer signals derived from an accelerometer; and determining one or more parameters of wind at the accelerometer based on the one or more accelerometer signals.

Abstract: A method, comprising: obtaining one or more accelerometer signals derived from an accelerometer; and determining one or more parameters of wind at the accelerometer based on the one or more accelerometer signals.

Abstract: A method of inhibiting activity or expression of one or more 3?-oxidoreductase enzymes that share a common catalytic site and convert androstanediol to DHT. The method comprises introducing one or more agents into cells that comprise the one or more 3?-oxidoreductase enzymes, wherein said one or more agents: i) inhibit function of one or more of said enzymes; ii) inhibit translation of mRNA encoding said enzymes; iii) disrupt or delete genes encoding said enzymes; or a combination thereof.

Abstract: A Y-shaped refractory anchor, a plurality of Y-shaped refractory anchors, and a method of installing a plurality of Y-shaped refractory anchors in a hexagonal pattern is disclosed. The Y-shaped refractory anchor comprises a singular rectangular folded metal plate comprising a stem that comprises at least one tapered triangular section to be welded to a backing surface and a folded stem base and a branch section comprising two branches, wherein the singular metal plate is folded together at the stem base, such that the stem of the Y-shaped anchor is twice as thick as the two individual branches.

Abstract: A method, comprising: obtain one or more accelerometer signals derived from an accelerometer; and determining one or more parameters of wind at the accelerometer based on the one or more accelerometer signals.

Abstract: A method, comprising: obtain one or more accelerometer signals derived from an accelerometer; and determining one or more parameters of wind at the accelerometer based on the one or more accelerometer signals.

Abstract: A method, comprising: obtain one or more accelerometer signals derived from an accelerometer; and determining one or more parameters of wind at the accelerometer based on the one or more accelerometer signals.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to identify user presence to a meter. An example apparatus includes a user input receiver to obtain presence information from a panelist via a prompt displayed by a user interface of the apparatus, the presence information indicating that the panelist is present at the meter separate from the apparatus, a configuration controller to package the presence information and insert an indication in the packaged presence information, the indication indicating the packaged information is to be sent to the meter via a remote server, and a wireless transceiver to transmit the packaged presence information to the remote server.

Abstract: Embodiments generally relate to a device comprising at least one signal input component for receiving a bone conducted signal from a bone conducted signal sensor of an earbud; memory storing executable code; and a processor configured to access the memory and execute the executable code. Executing the executable code causes the processor to: receive the bone conducted signal; determine at least one speech metric for the received bone conducted signal, wherein the speech metric is based on the input level of the bone conducted signal and a noise estimate for the bone conducted signal; based at least in part on comparing the speech metric to a speech metric threshold, update a speech certainty indicator indicative of a level of certainty of a presence of speech in the bone conducted signal; update at least one signal attenuation factor based on the speech certainty indicator; and generate an updated speech level estimate output by applying the signal attenuation factor to a speech level estimate.

Abstract: A Y-shaped refractory anchor, a plurality of Y-shaped refractory anchors, and a method of installing a plurality of Y-shaped refractory anchors in a hexagonal pattern is disclosed. The Y-shaped refractory anchor comprises a singular folded metal plate comprising a stem that comprises at least one triangular section to be welded to a backing surface and a folded stem base and a branch section comprising two branches, wherein the singular metal plate is folded together at the stem base, such that the stem of the Y-shaped anchor is twice as thick as the two individual branches.

Abstract: Embodiments of the disclosure relate to methods, apparatus and systems for authentication of a user. The described embodiments relate to obtaining ear biometric data for a user to be authenticated. The ear biometric data comprises one or more features characteristic of the user's ear canal and an associated fit metric indicative of a positioning of a personal audio device relative to the user's ear canal, the personal audio device comprising a transducer for application of acoustic stimulus to the user's ear to obtain the ear biometric data. The user may be identified as a particular authorised user based on one or more features and the associated fit metric.

Abstract: The present invention relates to methods of treatment of a disease or pathology of the central nervous system, an eating disorder, or substance use disorder, drug dependence/abuse and withdrawal therefrom comprising administering at least one N-phenylalkyl amphetamine derivative and pharmaceutical compositions comprising at least one N-phenylalkyl amphetamine derivative to an individual in need thereof.

Abstract: Example gravity gradiometers are described that utilize high precision resonant optical cavities to measure changes in gravitational forces at high sensitivities. In one example, a sensing system includes a gravity gradiometer and a controller. The gravity gradiometer includes a first mirror and a second mirror arranged to form an optical cavity having an optical axis. The controller is configured to detect, responsive to displacement of at least one of the first mirror and the second mirror along the optical axis, a change in gravity gradient.

Abstract: Methods and compositions which are directed against catalytic site common to multiple 3 alpha-oxidoreductases. The compositions can be used for the treatment of prostate cancer.