Patents by Inventor David A. Williams

David A. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BCL11A microRNAs for treating hemoglobinopathies
    Patent number: 12350284
    Abstract: Embodiments herein provide specially designed synthetic BCL11A-targeting microRNAs for RNA polymerase II expression, and methods of use to treat hemoglobinopathies, such as sickle cell disease or thalassemia, by increasing the expression levels of fetal hemoglobin levels.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: July 8, 2025
    Inventors: David A. Williams, Swaroopa Guda
  • Compositions and methods to treating hemoglobinopathies
    Patent number: 11739329
    Abstract: Embodiments herein provide specially designed synthetic BCL11A-targeting microRNAs for RNA polymerase II expression, and methods of use to treat hemoglobinopathies such as sickle cell disease or thalassemia by increasing the expression levels of fetal hemoglobin levels.
    Type: Grant
    Filed: August 17, 2021
    Date of Patent: August 29, 2023
    Assignee: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Michael Milsom, David A. Williams, Richard Gregory
  • Compounds for treating Rac-GTPase mediated disorder
    Patent number: 11685733
    Abstract: This disclosure relates to certain compounds that are effective in the treatment of a Rac-GTPase mediated disorder (e.g., acute lymphoblastic or chronic myelogenous leukemia), as well as methods for the manufacture of and the use of these compounds (e.g., for treating a Rac-GTPase mediated disorder).
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: June 27, 2023
    Assignee: Children's Medical Center Corporation
    Inventor: David A Williams
  • Compounds for treating Rac-GTPase mediated disorder
    Patent number: 11427574
    Abstract: This disclosure relates to compositions including certain compounds identified by a quantitative, high throughput assay to be effective in the treatment of a Rac-GTPase mediated disorder (e.g., acute lymphoblastic or chronic myelogenous leukemia), as well as methods for the manufacture of and the use of these compounds for treating a Rac-GTPase mediated disorder.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: August 30, 2022
    Assignee: Children's Medical Center Corporation
    Inventors: David A Williams, Serena De Vita
  • VECTORS AND COMPOSITIONS FOR TREATING HEMOGLOBINOPATHIES
    Publication number: 20220259594
    Abstract: The invention provides improved gene therapy vectors, compositions, and methods.
    Type: Application
    Filed: January 28, 2022
    Publication date: August 18, 2022
    Inventors: Gabor Veres, David A. Williams
  • Vectors and compositions for treating hemoglobinopathies
    Patent number: 11261441
    Abstract: The invention provides improved gene therapy vectors, compositions, and methods.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: March 1, 2022
    Assignees: bluebird bio, Inc., Children's Medical Center Corporation
    Inventors: Gabor Veres, David A. Williams
  • Wheel front face
    Patent number: D942913
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: February 8, 2022
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A Williams
  • Wheel front face
    Patent number: D959348
    Type: Grant
    Filed: February 4, 2019
    Date of Patent: August 2, 2022
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A Williams
  • Wheel front face
    Patent number: D959349
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 2, 2022
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D960064
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: August 9, 2022
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D960066
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: August 9, 2022
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Spray paint applicator
    Patent number: D964833
    Type: Grant
    Filed: May 24, 2020
    Date of Patent: September 27, 2022
    Assignee: AERVOE INDUSTRIES, INC.
    Inventors: David A. Williams, Keiran Creek
  • Wheel front face
    Patent number: D1008921
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: December 26, 2023
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1008923
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: December 26, 2023
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1009747
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: January 2, 2024
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1010535
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: January 9, 2024
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1032445
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: June 25, 2024
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1032446
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: June 25, 2024
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1032447
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: June 25, 2024
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams
  • Wheel front face
    Patent number: D1032448
    Type: Grant
    Filed: November 16, 2021
    Date of Patent: June 25, 2024
    Assignee: WHEEL GROUP HOLDINGS, LLC
    Inventor: David A. Williams